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1 02, 2025

Does Elderberry really work as a natural cure for colds?

By |2025-02-01T19:51:27+02:00February 1, 2025|Dietary Supplements News, News|0 Comments


As Americans sniffle and sneeze through the cold and flu season, demand for elderberry has never been higher.

These dark purple berries, packed with antioxidants and vitamins, have been used in folk medicine for centuries to treat everything from fever and infections to dental pain and sciatica. In medieval Europe, people even thought they could help you live longer.

Today, elderberry is touted as a miracle cold and flu remedy, with wellness influencers claiming it can shorten symptoms and speed up recovery. But before you race to the store, here’s the catch: the science behind its healing powers is shaky at best.

Elderberries supplements have flooded the market in recent years, becoming a multi-million dollar industry. orestligetka – stock.adobe.com

“The few studies that exist are often industry-supported,” Thomas Russo, professor and chief of infectious disease at the University at Buffalo, told Verywell Health. “People are spending a lot of money on an unproven supplement.”

Last year alone, consumers spent a whopping $175 million on elderberry syrups, teas, capsules, and powders, according to an analysis by the Nutrition Business Journal, as first reported by The Washington Post. 

One industry-funded study found that international travelers who took elderberry supplements before, during, and after long-haul flights recovered faster and experienced fewer cold symptoms than those who did not. 

Another 2020 review of five studies concluded that elderberry could reduce the duration and severity of symptoms like fever, headache, runny nose, and congestion if taken within 48 hours of feeling sick. 

But it’s not all good news. Several other studies have found “no evidence” that elderberry shortens the duration or severity of flu-like symptoms in children or adults.

The jury is still out on whether elderberry can alleviate cold and flu symptoms. New Africa – stock.adobe.com

That said, experts agree elderberries may still offer some health perks, even if the science isn’t ironclad.

“It’s very high in vitamin C, dietary fiber, and antioxidants like phenolic acids, flavonols, and anthocyanins,” Angel Planells, a registered dietitian nutritionist, told Real Simple. 

Vitamin C boosts the immune system, supports wound healing and promotes healthy skin, while antioxidants help reduce inflammation, lower cholesterol, and improve blood pressure.

Elderberry’s fiber content also benefits gut health, digestion, and immune system function. And it may help manage blood sugar, especially for those with diabetes.

“The phytonutrients and polyphenols in elderberry help the body to process glucose more efficiently,” Trista Best, a registered dietician, told Health. 

Elderberry supplements are sold in syrups, teas, capsules, powders and lozenges. tynza – stock.adobe.com

The plant may also offer disease prevention benefits. “Elderberry does contain antioxidants that can, in general, reduce the free radicals and oxidative stress that lead to chronic disease,” Kate Ingram, a registered dietitian, said in an interview with Fortune. 

Free radicals are highly reactive and unstable molecules that can damage cells and contribute to an array of health conditions, such as cancer, asthma, diabetes, and dementia. 

If you’re considering adding elderberries to your routine, there are a few things you should keep in mind. 

The Food and Drug Administration classifies elderberry as a dietary supplement, meaning it doesn’t undergo the same rigorous review as medications. Thus, its safety and effectiveness aren’t always guaranteed.

While supplements are widely available, you can also eat the berries — just make sure they’re cooked. Raw or unripe elderberries, along with their leaves and stems, contain cyanide-producing substances and can cause serious stomach issues like nausea and vomiting.

If you’re on prescription medication, you should check with your doctor before eating elderberries. “There are potential interactions with some diuretics, diabetic medications, chemotherapy medications, laxatives, asthma medications such as theophylline, and any drugs that suppress the immune system,” Planells said. 

People under 18, as well as those pregnant or breastfeeding, should also be mindful of using any supplements. While short-term use of elderberry appears safe for most people, its safety with long-term use still requires further research.



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1 02, 2025

XRP Price Prediction for February 1

By |2025-02-01T19:50:29+02:00February 1, 2025|Crypto News, News|0 Comments

Cover image via U.Today

Disclaimer: The opinions expressed by our writers are their own and do not represent the views of U.Today. The financial and market information provided on U.Today is intended for informational purposes only. U.Today is not liable for any financial losses incurred while trading cryptocurrencies. Conduct your own research by contacting financial experts before making any investment decisions. We believe that all content is accurate as of the date of publication, but certain offers mentioned may no longer be available.

The market has turned back to red again, according to CoinStats.

Article image
XRP chart by CoinStats

XRP/USD

The rate of XRP has fallen by 3.48% since yesterday.

Article image
Image by TradingView

On the hourly chart, the price of XRP is going up after setting a local support level of $2.9466. At the moment, one should focus on the vital zone of $3. If the daily bar closes above it, there is a possibility of an upward move to the $3.0631 mark soon.

Article image
Image by TradingView

On the bigger time frame, the rate of XRP is far from the key levels.

Related

Ethereum (ETH) Price Prediction for January 31

As neither side is dominating, ongoing sideways trading in the range of $2.90-$3.10 is the more likely scenario.

Article image
Image by TradingView

From the midterm point of view, the situation is similar. If the picture remains the same until the end of the week, traders are likely to witness consolidation in the area around $3 by mid-February.

XRP is trading at $2.9725 at press time.

Disclaimer: The opinions expressed by our writers are their
own and do not represent the views of U.Today. The financial and market information
provided on U.Today is intended for informational purposes only. U.Today is not
liable for any financial losses incurred while trading cryptocurrencies. Conduct
your own research by contacting financial experts before making any investment
decisions. We believe that all content is accurate as of the date of publication,
but certain offers mentioned may no longer be available.

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1 02, 2025

Uniswap V4 is here: A new era begins today for DeFi

By |2025-02-01T19:11:53+02:00February 1, 2025|News, NFT News|0 Comments


Uniswap v4 is live: new era for DEX leader

Uniswap v4 is now live, marking an important step for the DeFi industry . Following timelines announced in the previous week, the launch is now official and available to all.

Following the success of v2 and v3, which processed over $2.75 trillion in volume without ever being hacked, the new version offers greater efficiency and customization. The protocol is active as of now on all major blockchains, such as Ethereum, Polygon, Arbitrum, OP Mainnet, Base, BNB Chain, Blast, World Chain, Avalanche and Zora Network.

Among the main new features, new hooks are now available. These modular tools allow you to customize liquidity pools, swaps and fees in a flexible way. It will be possible to use “Limit” orders, of “Time Weighted Average Market Maker” trades, and also make non-productive liquidity, “Out of Range” efficient.

Among other new features, the costs of creating liquidity pools will be reduced by 99.9%. It will also be possible to use ETH again for trading without the need to use the “wrapped” version wETH.

We have written a dedicated article on Version 4 of Uniswap that you can consult to fully understand this new update.

Security, audits and the future of the Uniswap ecosystem

Security was a top priority for this update.

The code passed nine independent audits and a $2.35 million security competition. In addition, the largest bug bounty in history was offered, with a $15.5 million reward .

The release of Uniswap v4 not only improves efficiency, but opens up new development opportunities. Uniswap to date, has created a true ecosystem, also accomplice to the work done on the proprietary layer 2 “Unichain”, scheduled for mainnet by current quarter.

The market has not reacted to an already expected news that does not directly impact the UNI token. UNI ‘s price remains at $12.5, up +4% on the daily but at a -5% from early 2025.

 





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1 02, 2025

XRP May Face Sell-Off If History Turns Out True

By |2025-02-01T17:49:12+02:00February 1, 2025|Crypto News, News|0 Comments

Cover image via www.freepik.com

Disclaimer: The opinions expressed by our writers are their own and do not represent the views of U.Today. The financial and market information provided on U.Today is intended for informational purposes only. U.Today is not liable for any financial losses incurred while trading cryptocurrencies. Conduct your own research by contacting financial experts before making any investment decisions. We believe that all content is accurate as of the date of publication, but certain offers mentioned may no longer be available.

In the last 24 hours, XRP has plunged below the critical $3 level, losing more than 10 cents in its free fall. The sharp decline might signal that XRP could repeat its history in February. Notably, XRP usually underperforms in the second month of the year.

Historical trends highlight February weakness

According to Cryptorank data, XRP has an average monthly return of -3.00% for February. Since 2014, XRP has only finished in the green four times, with the highest percentage return in 2022. In that year, XRP registered a 26.3% increase in value.

Related

XRP 800 Million Surge: Activity Skyrockets, But What About Price?

The other three years of positive performances were in 2016, 2019 and 2024, with average monthly returns of 23.8%, 1.13% and 17.1%, respectively.

Conversely, XRP performed poorly in 2014, with a 33.4% decline. Aside from 2017, 2018 and 2021, with a negative growth of 12.3%, 22.1% and 14.8%, respectively, all other declines were below 10%.

Article image
DOGE Historical price data. Source: Cryptorank

Market observers consider this a plus for XRP as any sell-off that will occur might not adversely impact the coin. While acknowledging history leans toward an average of 3% cumulative loss, XRP could still flip the pattern and close February in the green.

Analysts highlight the broader cryptocurrency dynamics, which indicate the new U.S. administration remains pro-crypto as an indicator.

Can XRP reverse course?

Additionally, Ripple’s move to get included in the proposed U.S. crypto strategic reserve, if it scales through, could transform the price outlook in a flash. This is because it could drive up demand for XRP and increase its value, pushing it to test the $4 mark.

Related

Ripple CTO Proud to Announce Crucial New Feature on XRPL Which Benefits RLUSD

Brad Garlinghouse, Ripple’s CEO, recently stated that the company was pushing for inclusion in line with the current administration’s interest in supporting American tech organizations. However, critics have pushed back at this narrative as largely self-serving.

As of this writing, XRP was trading at $2.98, a 3.69% decline in the last 24 hours. As investors slow down on market activities, the trading volume has dipped by 4.59% to $4.46 billion.

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1 02, 2025

Green tea-derived nanosilver complex displays anti-melanoma activity

By |2025-02-01T15:49:25+02:00February 1, 2025|Dietary Supplements News, News|0 Comments


Credit: Nadezhda Ivanova

Melanoma is a fast-progressing skin cancer characterized by a high mortality rate after metastasis. Local chemotherapy could be considered a therapeutic approach only in stage 0 of progression (in situ melanoma) and in the postoperative phase after surgical removal of suspected skin lesions. For this purpose, drugs such as Imiquimod, 5-Fluorouracil, Dacarbazine, and Doxorubicin have been tested and shown positive effects. Recently, metal nanoparticles as separate therapeutic units or drug carriers have also fallen into the research focus.

Silver nanoparticles (AgNPs), in particular, are widely recognized as multifunctional tools in nanomedicine, drug delivery, and theranostics. They exert wide-spectrum antimicrobial and anti-tumor properties but their pharmacological effects are in a tight bond with the so-called “surface functionality.” For example, negatively charged and spherical particles are proven less toxic than positively charged particles, especially irregularly shaped (e.g., rods, wires, etc.). Still, because of this, the former are less potent anti-cancer agents.

Contemporary pharmaceutical development relies very much on eco-friendly technologies (often referred to as “green” technologies) that avoid the use of toxic solvents and reagents. This research has implemented one such method based on Camellia sinensis (green tea leaves) as a natural reducer of silver ions.

To achieve enhanced antimicrobial and anti-tumor activity, the thus obtained AgNPs were further conjugated to chlorhexidine (Cx+)—a broad-spectrum antimicrobial agent and a cationic surfactant. Indeed, the AgNP-Cx+ complexes have shown highly increased antimicrobial properties, about 18-fold stronger anti-melanoma activity, and 3 times better tumor selectivity compared to the non-functionalized AgNPs.

The most valuable outcome of this new study, published in the journal Pharmacia, was the establishment of an adhesive patch prototype as a topical dosage form for the AgNP-Cx+ complex.

The used polymers, Hydroxypropyl methylcellulose and Eudragit RS, demonstrated a lack of negative interference with the antiproliferative action of the active agent but also ensured twice as high activity and even better selectivity against the tumor cells.

More information:
Nadezhda Antonova Ivanova, Anti-melanoma activity of green-produced nanosilver-chlorhexidine complex, Pharmacia (2025). DOI: 10.3897/pharmacia.72.e143419

Provided by
Pensoft Publishers

Citation:
Green tea-derived nanosilver complex displays anti-melanoma activity (2025, January 31)
retrieved 1 February 2025
from https://phys.org/news/2025-01-green-tea-derived-nanosilver-complex.html

This document is subject to copyright. Apart from any fair dealing for the purpose of private study or research, no
part may be reproduced without the written permission. The content is provided for information purposes only.





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1 02, 2025

Here is Doge Price If Its Market Cap Hits $397B or $2.02T

By |2025-02-01T15:48:09+02:00February 1, 2025|Crypto News, News|0 Comments

Dogecoin will hit a new all-time high if its market cap soars to unprecedented levels like $397 billion or $2.02 trillion. 

Dogecoin’s performance over the past few weeks has been far from impressive. Despite the recent relief rally in the broader crypto market, the token has been trading around the $0.3 mark in the past few days. 

Dogecoin has experienced a slight decline of 0.2% in the past 24 hours and 0.68% over the past 30 days. However, it has incurred more losses in the past week, totaling 6.16%. 

Despite this decline, many investors are optimistic that Dogecoin will still record another major rally this cycle, as it did in the 2020/2021 bull market. 

Amid these projections, some wondered how high Dogecoin’s price will soar if its market cap soars to $397 billion or $2.02 trillion. It is worth mentioning that these valuations represent that of Ethereum (ETH) and Bitcoin (BTC), respectively.  

Dogecoin Price at Bitcoin and Ethereum Market Cap 

Therefore, we estimated the price of Dogecoin if its valuation equals that of the two largest cryptocurrencies in the world: Bitcoin and Ethereum. 

At press time, Dogecoin ranks as the eighth-biggest cryptocurrency, with a market cap of $48.41 billion. It is currently priced at $0.3274 per token. Its daily volume is up 36.61% to $1.75 billion, representing 3.61% of the global crypto trading volume.  

Currently, Dogecoin has a circulating supply of 147,861,546,383 (147.86 billion) tokens. 

Price of Dogecoin at Bitcoin Market Cap 

For context, Bitcoin remains the undisputed world’s largest cryptocurrency, with a market cap of $2.02 trillion. To equal Bitcoin’s market cap, Dogecoin would have to soar 4,072% from its current valuation of $48.41 billion. 

If DOGE embarks on a 4,072% rally and equals Bitcoin’s market cap, its price will rise to $13.65 per token, assuming its circulating supply remains stable at 147.86 billion tokens. 

At this projected price, a portfolio of 100,000 DOGE worth $32,740 at the current value of $0.3274 per token will skyrocket to $1.36 million. 

DOGE Price at Current Ethereum Market Cap 

Ethereum’s current market cap of $397.33 billion makes it the second-biggest cryptocurrency in the world. For Dogecoin to equal this market cap, it must rise 720% from its current valuation of $48.41 billion. 

Applying the same growth rate to Dogecoin’s price will push it to around $2.68 per token, assuming DOGE’s circulating supply remains relatively stable. 

At a price of $2.68, a portfolio of 100,000 DOGE will be worth $268,000 compared to its current value of $32,740. 

Can Dogecoin Rise to $2.68 or $13.65? 

Dogecoin must rise 720% and 4,072%, respectively, to reach the price targets of $2.68 and $13.65. Such astronomical rallies require Dogecoin to have broader utility and widespread adoption. 

The token could also achieve this feat if it is integrated into major payment networks, with more prominent figures beyond Elon Musk endorsing it for mass adoption from retail and institutional investors. 

Interestingly, institutions are showing significant interest in Dogecoin, as reflected in the number of ETF applications submitted by prospective issuers, like Bitwise.

Interestingly, analysts affiliated with the crypto trading platform Changelly believe that Dogecoin can hit the $2.68 target by September 2032, nearly eight years from now. However, they expect DOGE to wait another eight years before it hits the $13.65 target by 2040. 

Whether DOGE will ever soar to $2.68 or $13.65 in its lifetime remains to be seen. 

 

DisClamier: This content is informational and should not be considered financial advice. The views expressed in this article may include the author’s personal opinions and do not reflect The Crypto Basic opinion. Readers are encouraged to do thorough research before making any investment decisions. The Crypto Basic is not responsible for any financial losses.

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1 02, 2025

ABC Conclave Bangkok 2024: A Groundbreaking Nexus of AI, Web3, and Gaming!

By |2025-02-01T15:07:51+02:00February 1, 2025|News, NFT News|0 Comments


The ABC Conclave Bangkok ‘24, one of the most anticipated Web3 and AI summits, concluded with resounding success, bringing together visionaries, industry leaders, and global pioneers to shape the future of decentralized technologies. Held on 11- 12, Nov, ‘24, at Southeast Asia’s new world-class Entertainment Venue Emsphere – UOB LIVE, Bangkok, Supported by the Digital Economy Promotion Agency (DEPA), Associated with the Malaysia Digital Economy Corporation (MDEC), and hosted by AlphablockZ, the conclave showcased cutting-edge discussions, groundbreaking innovations, and strategic collaborations in AI, Web3, and Gaming.

Bangkok edition of ABC Conclave witnessed 5,500+ attendees, 100+ expert speakers, 1000+ blockchain developers, and 500+ innovators exploring the cutting-edge convergence of AI, Web3, and Gaming under the theme “Next-Gen Nexus: Uniting AI, Web3, and Gaming.” The event was a powerhouse of insightful panel discussions, fireside chats, groundbreaking tech talks, and exclusive networking opportunities, setting the stage for Thailand’s emergence as a Web3 leader in Southeast Asia.

With 30+ insightful seminars and unparalleled networking opportunities, the conclave fostered meaningful connections and ignited ideas shaping the future of digital assets. Bangkok solidified its position as a global hub for the blockchain and crypto communities through this impactful event.



Bangkok ‘24 edition brought together global leaders in AI, Web3, and gaming to shape the future of decentralized technologies. The event featured expert-led panels, interactive tech talks, and in-depth discussions on blockchain gaming, DeFi, AI-driven transformation, and digital asset tokenization. Industry pioneers shared insights on Southeast Asia’s expanding role in Web3 adoption and the latest advancements in decentralized ecosystems.

The conclave culminated in the prestigious ABC Awards Night, recognizing innovators in blockchain, AI, and fintech. With its thought-provoking discussions, expert insights, and unparalleled networking opportunities, ABC Conclave Bangkok 2024 reaffirmed its status as a premier hub for industry innovation and the decentralized future.

Key Highlights from ABC Conclave Bangkok 2024:

Ravindra Kumar, Founder & CEO, Self Chain; ‘’Web3 has been technical for a lot of folks, its not straightforward to work with web3, for it’s too technical for the retail users.’’

Datuk Fadzli Abdul Wahit, Senior Vice President, Head of Digital Transformation and Head of Digital Investment Office, Malaysia Digital Economy Corporation; ‘’ I represent the MDEC which is an agency under the purview of the Ministry of Digital which is spearheading Malaysia’s Digital Transformation journey forward and our participation today holds a very special significance as Malaysia prepares to take the helms of ASEAN Leadership in 2025 and we are excited to share our vision for digital innovation across the region.’’

Saen Witthayaphatthanaphorn, Policy Manager, British Chamber of Commerce Thailand
“In today’s world, Digital Transformation is powerful for us shaping of how we work and communicate to how we innovate and solve global challenges.’’

Wiroon Siewsirithaworn, Project Manager of Digital Platform and Service Promotion Department, DEPA; ‘’We plan to be half of digital economy in Asia and lets give a bit of background- the EEC Thailand was initiated by Thai Government and the goal is to position Thailand to center player of the ASEAN.’’

Vandad Hatefi, Head of Business Development, Serenity Shield; ‘’I think in Web3, Data Storage & Security will play a significant role and even more than Web2 because blockchain is still a young technology and we are in an early stage of this technology and we have to build a strong foundation, right?’’

Yat Siu, Co-founder & Chairman, Animoca Brands; ‘’Why gaming is important for us in space- First of all, All Gamers virtually use Digital Assets, they are already familiar with things like virtual currency and of course with digital assets. There are 3.4 Billion people who play games today which is more than than about 60-65% of the World’s Internet.’’

Abdul Osman, Ceo, Gora; ‘’If anybody can run a node, that means, the more nodes that are running, the more secure the network is, and that’s why we (Gora) focused on nodes being able to deploy at a single click.’’

Web3 leaders Sebastien Borget and Yat Siu delivered an inspiring fireside chat on why bear markets are the best time for innovation moderated by Ken Rutkowski. They emphasized sustainable development, community building, and creating long-term value in decentralized ecosystems rather than chasing short-term hype.

The event also focused on other key topics such as:

●      Thailand’s Path to Global Web3 Leadership

●      The Future of Blockchain Gaming & User-Generated Content

●      Real-World Asset Tokenization & The Future of Finance

●      The Builders’ Mindset: Thriving in a Bear Market

●      AI & Web3: A New Era of Innovation

●      The Future of Web3 Gaming: From Play-to-Earn to Community-Driven Models

●      Convergence of TradFi and DeFi

●      Security in a Trustless Ecosystem

ABC Conclave Bangkok edition featured an exceptional lineup of speakers who delivered groundbreaking insights during the event on 11 -12, Nov ‘24:

●      Yat Siu, Co-Founder & Chairman, Animoca Brands

●      Sebastien Borget, Co-Founder & COO, The Sandbox

●      Gabby Dizon, Co-Founder, Yield Guild Games

●      Sergej Kunz, Co-Founder, 1inch

●      Datuk Fadzli Abdul Wahit, Senior Vice President, Head of Digital Transformation and Head of Digital Investment Office, Malaysia Digital Economy Corporation

●      Danesh Jothiprahasam, Head, Emerging Tech & GBS, Digital Investment Office, Malaysia Digital Investment Office

●      Wiroon Siewsirithaworn, Project Manager of Digital Platform and Service Promotion Department, DEPA

●      Saen Witthayaphatthanaphorn, Policy Manager, British Chamber of Commerce

●      Pawee Jenweeranon, Digital Consultant, The World Bank Group

●      Ravikant Agrawal, Director of Growth, Privado ID

●      Sheldon Hunt, Head of the Cardano Ecosystem, Emurgo

●      Iana Pugachova, Co-founder, SynergyLabs / ICP Hub

●      Andrew Azarias, Regional Marketing – SEA, Trust Wallet

●      Gracy Chen, CEO, Bitget

●      Ken Rutkowski, Founder, METAL

●      Funsho Ajibade, Founder & CEO, Sheertopia

●      Abdul Osman, CEO, Gora

●      Tobias Bauer, Partner & Co-Founder, TBV

●      Belinda Lim, Country Manager (SG), Sandbox

●      Dyma Budorin, Co-Founder & CEO, Hacken

●      Coach K Crypto, CEO, Coach K Productions Ltd

●      Shawn Tan, General Partner, Trive Digital

●      Faraj Abutalibov, Co-Founder & CBDO, CrossCurve by EYWA

●      Ramani Ramachandran, CEO, Router Protocol

●      Steve Good, CEO, Dreams Quest

●      Kevin Soltani, CEO, GIMA Group

●      Matthias Sheikh Mende, Founder and Co-Founder, Bonuz / Dubai Blockchain Center

●      Stefano Virgilli, Business Partner, Technology and Communication, DWF Labs

●      Brent Fulfer, General Partner, TBV

●      Arpit Sharma, COO, PWR Labs

●      Alex Latour, Content Creator, The Thaiger

●      Herbert Sim, Founder, The BitcoinMan

●      Elliana Jin, Principal, TBV

●      Ken Tanaka, CMO / KOL, Tenset CATAMOTO

●      Jirayu Charoenyos, Core Team, Thammasat Blockchain Community

●      Panai Charoensuk, Ex-President, Chulalongkorn Blockchain Society

●      Nichanun Thongprasert, President, Thammasat Blockchain

  • Kirubakaran Reddy, Founder, ABC Conclave & AlphaBlockZ

●      Preetam Rao, CEO, QuillAI

●      Mayur Relekar, Founder & CEO, Arcana Network

●      Corey Wilton, CEO, Mirai Labs

●      Amar Bedi, CEO, Tashi Networks Pie Ltd

●      Mark Rydon, CSO, Aethir

●      Tatsuya Kohrogi, Head of APAC, Ginco SG

●      Mary Pedler, Founder, Input Comms

●      Ahmed Salama, Founder / CGO, Adltix / Emerge

●      Kazama Vanichjakvong, Co-Founder & CXO, DTC Group

●      Geoff McAlister, Chief Risk Officer, M2

●      Barami Rai, Co-Founder & CEO, DTC Group

●      Alex Fazel, Chief Partnership Officer, SwissBorg

●      Alnura Belyalova, Director of PR, Input Comms

●      Mustafa Guler, CEO and Founder, Edu3Labs

●      Vandad Hatefi, Lead – Business Development, Serenity Shield

●      Mat Milbury, CEO, Tenset

●      Kanji Low, COO and Founder, Presence

●      Harrison Goldsmith, Business Development Lead, Owl Protocol

●      Bruno Calabretta, Hub Manager, ICP Hub ID – Disruptives

●      Moe Iman, Founder and CEO, Founders Hub Network

●      Nick Garvin, Growth & Comms, Founders Hub Network

●      Arravind Prabu, CEO, Cryptobilis

●      Ken Nizam, Founder & CEO, AsiaTokenFund Group

●      Cecilia Wong, Founder & CEO, yourPRstrategist

●      Wanrob Boontham, Head of Investment Banking & Tokenization, Token X Company Limited

●      Hira Siddiqui, Co-Founder & CEO, Plurality Network

●      Harpreet Singh Maan, Founder, Ikka.IO

●      Arseny Klekovkin, Managing Partner, G1 Ventures

●      Bob Sachathamakul, CEO, PSP Innovations

●      Akkaraphol Raebankoh, CEO, Blockly Thailand

●      Tao Santimakorn, Chief Business Development Officer, Translucia

●      Dmitry Chirun, CTO, Chateau Capital

●      Renz Chong, Co-founder & CEO, BreederDAO

●      Leah Callon-Butler, Director, Emfarsis

●      Yura Mizin, Founder & CEO, Cryfi

●      Subash Sukhdeo, CMO, TaskOn

●      Nares Laopannarai, Founder, Ricco

●      To Madeira, Co-founder, Matr1x

●      Vikram Bhushan, Co-Founder, EIKO

●      David Nikzad, CEO, Orthogonal Thinker

●      Anthurine Xiang, Co-founder/CMO, EthStorage & QuarkChain

●      Hao Jun Tan, CEO, Chateau

●      James Lucas, Managing Partner, GC Capital

●      Andrey Kuznetsov, Chief Tech, Haqq

●      Vaibhavv Ali, Founder | Host, CryptoniteUAE | Roadcast

●      Agastya Samat, Founder, Universal Health Token

●      Hardiyanto Gunawan, Global Partnership Manager, BeInCrypto

●      Max Andonov, Business Development Associate, Cointelegraph

●      David Rutkovsky, Director of Global Business Development, Bitlayer Labs Ltd.

●      Keith Dawson, Founder & CEO, Qualoo

ABC Conclave Awards – Honoring Industry Pioneers

The much-anticipated ABC Awards Night celebrated trailblazers in AI, Web3, and gaming. Some of the prestigious winners included:

“We are thrilled with the overwhelming success of ABC Conclave Bangkok 2024,” said Kirubakaran Reddy, Founder of ABC Conclave & AlphaBlockZ. “This event is a testament to the power of collaboration, innovation, and vision. Thailand is poised to become a leader in Web3, and ABC Conclave is committed to fostering this transformation by bringing together the brightest minds in the industry.”

The Bangkok edition of the ABC Conclave ‘24 was supported and sponsored by:

  • Supporting Partner: DEPA
  • Association Partner: MDEC
  • Organized by: AlphaBlockz
  • Title Sponsor: Self Chain
  • Powered By :  Tenset  &  Gora
  • Legendary Sponsors: Sersh, Atc, Famex, Serenityshield, Sheertopia
  • Epic Sponsors: Dreamsquest, Icp, Lore, Ozone, Cros, Adltix, Edu3labs, Eiko
  • Rare Sponsors: Qoal, Memeprof, Victor Games, Kix Digital, Arcana
  • Prime Media Partner: The Thaiger
  • Official Media Partner: Coin Telegraph
  • Official Pr Partner: Zex Pr Wire
  • Exclusive Talkshow Partner : Dx Talks
  • Innovation Partner: Hack2skill

With its unparalleled thought leadership, pioneering discussions, and strategic collaborations, ABC Conclave Bangkok 2024 set the stage for the next era of AI, Web3, and gaming innovations.

About ABC Conclave

ABC Conclave 2024, hosted by AlphablockZ, aims to reach a global audience within the crypto community through dynamic social interactions.  It promises an exceptional lineup of esteemed Speakers, cutting-edge Projects, and esteemed Partners.

The event, hosted in Dubai and Bangkok, brings together visionaries, industry leaders, and entrepreneurs to discuss blockchain, cryptocurrency, and fintech. The Conclave serves as a catalyst for change, fostering knowledge exchange, debate, and shaping the future of cryptocurrencies. The primary goal is to ignite conversations about the potential of cryptocurrencies and accelerate their adoption worldwide. The event will be promoted through various platforms and influencer collaborations.

Stay tuned for the next edition of ABC Conclave!

For more details, visit www.abcconclave.com

For further details about the announcement, please contact:

Jagriti Jaiswal

CGO & Head of Partnerships | ABC Conclave
info@abcconclave.com





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1 02, 2025

Scientists discover how NAD energizes cells

By |2025-02-01T13:48:05+02:00February 1, 2025|Dietary Supplements News, News|0 Comments


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Scientists have found an explanation for how NAD affects the aging process. Johner Images/Getty Images
  • NAD is a molecule found in every living cell of the body that plays an important role in creating energy in the body.
  • Researchers from the University of Bergen, for the first time, show how mitochondria act as “reservoirs” to hold NAD, which plays an important role in creating energy in the body.
  • Scientists believe this finding may lead the way for new therapeutic options to combat aging and age-related diseases.

“NAD is an essential molecule that plays critical roles in all living cells — bacteria, plants, (and) animals,” Mathias Ziegler, MD, PhD, a professor in the Department of Biomedicine at the University of Bergen in Norway explained to Medical News Today.

“The fundamental role of NAD is in the retrieval of energy from food sources to make it available for cellular functions. Metaphorically speaking, NAD acts like a rechargeable battery storing energy retrieved from nutrients and then passing it on to fuel energy-demanding processes. The most important of such processes takes place in mitochondria, the cell’s powerhouse,” he continued.

Ziegler is the lead author of a new study that explains how mitochondria act as “reservoirs” to store NAD for cells to use.

However, as the amount of NAD in the mitochondrial “reservoirs” depletes with age, cells may not have enough NAD to function adequately.

Scientists believe this finding may lead to new therapeutic options aimed at raising NAD levels to combat aging and age-related diseases.

For this study, Ziegler and his team developed cellular models to look at how cells might react when NAD levels are reduced during the aging process.

Past research shows that NAD levels decline as we age, potentially causing increased levels of DNA damage and decreased cellular metabolism, both of which are linked to the aging process.

“Throughout the cell, NAD is also used as a chemical messenger to transmit information and to set switches to regulate key events such as cell division and DNA repair,” Ziegler explained.

“Unlike in the energy transmission function, when acting as a messenger molecule, NAD is degraded and needs to be resynthesized. In a variety of diseases, including neurodegenerative disorders and aging, these NAD-consuming processes may be over-activated. This will diminish NAD availability and eventually affect the efficiency of energy-demanding processes — which may explain at least part of the observed symptoms,” he said.

“In our study, we established and investigated for the first time a cellular model system that resembled the situation of chronically diminished NAD levels, thereby enabling us to study the mechanistic consequences,” he added.

During the study, researchers found that mitochondria act as a “reservoir” to hold NAD and supply it to the cell as needed.

“Previous studies had demonstrated that mitochondrial NAD plays an important protective role in situations of cellular stress,” Ziegler said. “However, how NAD exerts this role has remained unknown. Our investigation revealed that mitochondria can supply NAD when the demand for this molecule is excessive in other parts of the cell.”

Ziegler and his team also discovered that if mitochondria does not have enough NAD stored up, it can have a fatal consequence for the cell.

“Our study connects two hallmarks of aging, mitochondrial dysfunction and dysregulated NAD levels, indicating that excessive consumption of mitochondrial NAD might constitute a key factor leading to dysfunctional mitochondria and thus aging-associated diseases.”
— Mathias Ziegler, MD, PhD

“Our study has made an important contribution towards understanding the mechanistic basis for positive outcomes of various preclinical and some clinical studies of NAD supplementation approaches. Even though it is unlikely that such supplementation approaches will be able to cure the pathology, they could have positive effects on disease progression (i.e. slowing down progression) and dampening the symptoms,” Ziegler explained.

“This is also likely to be the case in aging, when the mitochondrial NAD reservoir is still sufficiently functional. Since we were able to identify the key players in the buffering function of mitochondria, we unraveled potential molecular targets for the development of therapeutic approaches specifically supporting this mechanism,” he added.

MNT had the opportunity to speak to Manisha Parulekar, MD, FACP, AGSF, CMD, director of the Division of Geriatrics at Hackensack University Medical Center and co-director of the Center for Memory Loss and Brain Health at Hackensack University Medical Center in New Jersey, about this study.

“NAD+ (the oxidized version of NAD) is a crucial coenzyme involved in hundreds of metabolic reactions, particularly those related to energy production, DNA repair, and cell signaling. It is not surprising that dysregulation of NAD+ levels, specifically a decline with age, is increasingly recognized as a possible significant contributor to both aging and a wide range of pathologies,” Parulekar said.

“While significant progress has been made in understanding the role of NAD+ in aging and disease, several key areas require further research. Could supplementing NAD precursors halt this process, what is the optimal dose for different age groups and health conditions? Research should explore how factors like age, sex, genetics, and underlying health conditions influence the response to NAD+ precursors.”
— Manisha Parulekar, MD, FACP, AGSF, CMD

MNT also spoke with Clifford Segil, DO, neurologist at Providence Saint John’s Health Center in Santa Monica, CA, about this study.

“NAD (is) a supplement that is closely related to vitamin B3 or niacin, and niacin is a supplement that we use to lower cholesterol,” Segil said.

“Part of what they said was that NAD in the study is related to mitochondrial problems. In neurology, mitochondrial problems are usually neuromuscular or muscle problems, so (it’s) pretty much accepted mitochondrial problems affect muscles in neurology. It’s not accepted that mitochondria affect dementia in neurology,” he explained.

“I’d like to see them say what dietary changes could try to increase NAD as we age. I’d also like to see them do NAD research on mitochondrial or muscle diseases because in neurology, mitochondrial diseases are most prevalent in muscular neurological problems,” he added,

Parulekar said that while completely halting the age-related decline of NAD+ is likely impossible, readers can take steps to mitigate the decline and maintain healthier levels.

“Strategies may include consuming foods rich in NAD+ precursors like dairy products, fish, poultry, (and) green vegetables. Daily exercise can also help stimulate mitochondrial biogenesis and increase energy demand,” she detailed.

Segil urged readers to consider oral NAD supplements rather than infusions for safety reasons.

NAD supplements vs. infusions

“Anytime you get a supplement infusion, which is an IV done outside of a hospital, there are large risks for infections, so I discourage any patient to get an IV or an infusion of any supplement. I think it’s safer just to continue oral supplements with vitamins and minerals. IV infusions of vitamins and supplements carries the risk of infection, and the risks of infection outweigh any potential benefits.”
— Clifford Segil, DO

“It is important to consult with a healthcare professional before starting any NAD+ supplementation regimen, especially if you have any underlying health conditions. They can help you interpret the existing research and determine whether NAD+ supplementation is appropriate for you,” Parulekar added.



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1 02, 2025

XRP Up 511% Yearly, How Much Higher Can It Go?

By |2025-02-01T13:47:06+02:00February 1, 2025|Crypto News, News|0 Comments

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Disclaimer: The opinions expressed by our writers are their own and do not represent the views of U.Today. The financial and market information provided on U.Today is intended for informational purposes only. U.Today is not liable for any financial losses incurred while trading cryptocurrencies. Conduct your own research by contacting financial experts before making any investment decisions. We believe that all content is accurate as of the date of publication, but certain offers mentioned may no longer be available.

According to data from the crypto ranking platform CoinGecko, XRP is up 511% yearly. In Q4, 2024 alone, XRP market capitalization gained 246%, according to a recent report by Messari. 

XRP began a bull run last November on expectations of a more crypto-friendly stance; for years, XRP prices were muted as a result of the Ripple SEC lawsuit initiated in 2020, which resulted in Ripple’s 2023 legal victory. Last August, Ripple was ordered to pay a $125 million fine related to sales to institutional investors, effectively ending the suit.

Article image
XRP Price Performance Chart, Courtesy: CoinGecko

Retail and large holder participation also picked up with on-chain data signaling whale accumulation. According to Messari, in Q4, 2024, new addresses increased 382% to 507,000, suggesting the onboarding of new users.

The anticipation surrounding the XRP ETF has also boosted XRP prices. Ripple Labs president Monica Long earlier remarked that an XRP ETF might “soon be a reality.” Most recently, Grayscale Investments has applied with the SEC to convert its XRP Trust into an ETF for listing on the New York Stock Exchange.

Related

What's Next for XRP? Ripple CEO to Reveal at Key Event

Aside from Grayscale, several firms have applied for XRP-based ETFs, demonstrating a rising institutional appetite for structured investment products in XRP. Purpose Investments, a Canadian asset management firm, has filed a preliminary prospectus for an XRP spot ETF.

Wisdom Tree filed an S-1 in December to launch an XRP ETF, following Bitwise, Canary and 21Shares’ submissions in October and November. RLUSD, Ripple’s USD-pegged stablecoin, was also launched in December, marking a significant milestone.

How much higher can it go?

As a result of the spike, XRP surpassed Tether (USDT), among others, to become the third-largest cryptocurrency by market capitalization, trailing only Bitcoin and Ethereum. At the time of writing, XRP was down 1.28% in the last 24 hours to $3.09 with a current market capitalization of $178.15 billion.

Related

XRP Hourly Death Cross: Is It Cause for Concern?

Back in 2018, XRP witnessed a similar rise, briefly surpassing ETH in market capitalization when both coins were worth roughly $22 billion. Is it possible that this might happen again?

Only time will tell — but XRP has further room for growth. ETH has a market capitalization of $404 billion, which is more than twice that of XRP.

In terms of price, eyes are on XRP breaking past its recent high of $3.4 and reaching $4 or possibly $5. Meanwhile, the daily SMA 50 at $2.6 has held up as XRP support since November 2024.

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1 02, 2025

A Groundhog Made Of Iced Tea Cans? 02/03/2025

By |2025-02-01T11:47:09+02:00February 1, 2025|Dietary Supplements News, News|0 Comments


 

 

Will the world-famous
groundhog Punxsutawney Phil see his shadow at his Gobbler’s Knob home in Pennsylvania on Feb. 2, predicting six more weeks of winter or an early spring? Lipton Hard Iced Tea says, “Who
Cares?” as the brand unveils its own “groundhog,” who is definitely throwing the approximately two-foot-tall Phil more than a little shade.

The nine-foot-tall groundhog
statue, made entirely out of 6,000 Lipton Hard Iced Tea cans, was built to launch the brand’s new 12-pack cans of its Citrus Green Tea Flavor.

“Can Daddy,” as the brand has
named him, weighs an estimated 250 lbs. and took the team tasked with building him more than 150 hours to complete. Can Daddy is currently making his way through Pennsylvania stopping for 
appearances on Jan. 31 in Pittsburgh. The brand has also erected a sun-powered “shadow billboard that will cast a hidden message on Saturday” at the Indiana, Pennsylvania, stop. Those in
attendance can also try samples of the Hard Iced Tea. Fans can follow his adventures on the brand’s Instagram platform.

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“We’re all about bringing fun and flavor to the moments that
matter,” said Lisa Texido, brand director at Lipton Hard Iced Tea, in a release. “Groundhog Day is an iconic tradition, and we wanted to take it to new heights—literally. Whether you’re raising
a can to winter or to an early spring, Lipton Hard Iced Tea is here to bring the good vibes.”

Fans of Chunk the Groundhog, the Instagram celebrity pet known for his love of stealing
vegetables, are in for their own Groundhog Day celebration. The brand has also teamed up with the creature’s creator for his own prediction on Feb. 2: What is his favorite flavor of Lipton Hard Iced
Tea? The results will be posted to Chunk’s social platforms.

The brand also has two fan contests with very different prizes. Those who want to make the Can Daddy statue their very own
can visit the brand’s Instagram and comment “Groundhog” on its Groundhog day post to be entered in the sweepstakes with that prize.

More traditionally, Lipton has also launched a
warm weather getaway contest, for which consumers need to log on to liptonhardtea.com/groundhogday to enter before “the sun sets” on Feb. 2.





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