Vitamin D is known to be essential to many aspects of human health — but a new study suggests that taking a certain form of it can have a negative effect.
The more potent and longer-lasting form, vitamin D3 (cholecalciferol) is produced naturally when the body is exposed to sunlight and is also found in animal products, while vitamin D2 (ergocalciferol)comes from plant or fungal sources, per the National Institutes of Health.
Researchers from the University of Surrey in the UK found that taking vitamin D2 can cause reduced levels of vitamin D3 in the body.
They made this determination by analyzing 11 randomized controlled trials including 655 adults, which showed that people taking vitamin D2 supplements had less vitamin D3 than those who did not take D2, according to a university press release.
The findings of the study — conducted along with the John Innes Centre and the Quadram Institute Bioscience in Norwich, England — were published in the journal Nutrition Reviews.
Taking vitamin D2 can cause reduced levels of vitamin D3 in the body, according to the UK study. SERSOLL – stock.adobe.comThe study’s trial included 655 adults. amenic181 – stock.adobe.com
“We have shown that vitamin D3, but not vitamin D2, appears to stimulate the type I interferon signaling system in the body – a key part of the immune system that provides a first line of defense against bacteria and viruses,” stated Professor Colin Smith, who led the above study. “Thus, a healthy vitamin D3 status may help prevent viruses and bacteria from gaining a foothold in the body.”
Professor Martin Warren, chief scientific officer at the Quadram Institute, confirmed in the release that vitamin D deficiency is a “significant public health concern,” particularly during the winter months.
“This collaborative research effort aligns well with the Quadram Institute’s mission to deliver healthier lives through food innovation to enhance the nutrient density of the food we eat,” he said. “Tackling this with the most effective form of vitamin D supplementation or fortification is of the utmost importance to the health of the nation.”
More research is needed to determine whether vitamins D2 and D3 affect the body differently Seventyfour – stock.adobe.com
More research is needed to determine whether vitamins D2 and D3 affect the body differently — and whether that could change doctors’ medical advice on which type to take, the researchers concluded.
There were several limitations to the analysis, the study findings noted.
For example, there were only a small number of studies with many differences among them, such as their duration, the amount and timing of doses, and how results were measured. There was also the potential for biases due to incomplete reporting of details.
The results could also be affected by factors such as the amount of sunlight exposure, as well as some people taking supplements and others eating vitamin-fortified foods, the researchers noted.
Some foods containing vitamin D3 include fatty fish, egg yolks, cod liver oil and fortified dairy and animal foods, health sources confirm. Vitamin D2 can be found in mushrooms, fortified foods and some plant/fungal-based supplements.
The study was supported by the Biotechnology and Biological Sciences Research Council (BBSRC).
Prominent research analyst Ash Crypto predicted at the beginning of the month that Bitcoin would drop closer to the $106,000 level in October, while Ethereum would drop near $3,800 or lower. His predictions proved to be correct.
However, Ash Crypto also predicted that the last quarter of the year would be Bitcoin’s most successful quarter. He said the asset’s price would soar to $150,000 and spark an altcoin season.
On October 1, crypto researcher Ash Crypto posted a bold prediction on his Twitter account about the crypto market’s movement for the remainder of the month and through the end of the year.
“I think we are seeing a pump to make everyone believe PUMPtober is real and soon we can get a nasty drop where Bitcoin dumps closer to the $106k level and ETH dumps near $3800 or lower, and everyone will think Uptober is canceled,” his tweet read.
The market crash last weekend proved him right.
The catalyst was President Trump’s aggressive announcement of a 100% tariff on Chinese products, which plunged the global crypto market. Bitcoin dropped to a low of $105,000, and Ethereum briefly sank as low as $3,500. The sell-off was even more severe for most other altcoins.
If this week’s events confirmed the first half of his prediction, then the second half offers hope to a market still reeling from a moment of sudden ruin.
Although Ash Crypto’s prediction for the rest of October paints a bleak picture, his forecast for the remainder of the year offers a welcome refuge for investors.
According to him, the crypto market will enter an unprecedented bull phase during the last quarter of 2025. This latest bear phase would send investors a message that the recent upward trend in crypto is finished, causing them to short en masse.
When pessimism is at its maximum, the market will reverse, producing massive percentage gains, likely starting in the last 10 days of October.
“Then October monthly will close with a massive % gain, and the Q4 parabolic pump will start, which will send BTC to $150k-$180k, ETH to $8k-$12k, and the TRUE alt season will finally begin, sending alts 10x-50x in just 3-4 months,” Ash Crypto predicted.
SNX price skyrockets over 150%, hitting $2.51 amid massive 1,500% surge in trading volume.
Launch of Synthetix’s new perpetual DEX on Ethereum sparks strong market excitement.
The native token of Synthetix has seen an impressive rise, surging more than 150% in a single day as investors flock back to the old protocols.
The dramatic price action caused SNX to be pushed out of the range of around $1.00 to over $2.35 with short-term highs of $2.51 in the trading session of Monday. The volume of trading shot up to an unprecedented $979 million, which is an incredible over 1,500% increase over the normal levels of daily activity in different exchanges.
According to market observers, there are a number of reasons why renewed investor confidence in the 2018-vintage token, which is older than more recent derivatives platforms by far, has been restored. The next perpetuals decentralized exchange will be launched on the Ethereum mainnet later this month, which has created a lot of excitement among derivatives traders around the world.
New Competition Reshapes DeFi Landscape
The recent difficulties of rival platforms Hyperliquid and Lighter have provided the established protocols with a chance to reclaim the market focus successfully. Synthetix is in a good position to take advantage of this changing competitive dynamic through its future perpetual exchange offering and infrastructure.
The project will also carry out a high profile trading competition on October 20, where influential influencers will be invited to showcase the capabilities of the platform. Such a strategic marketing campaign may shift a substantial amount of capital flows of competing trading platforms to the ecosystem and products of Synthetix.
Technical analysts observe that SNX has managed to overcome a four-year downward trend, and it may experience a long-term upward trend in the future. The token is currently trading at a level that it had not reached since the 2022 cryptocurrency market crash that wiped out valuations.
The strategic growth of Synthetix on Ethereum, Optimism, and Base networks will improve cross-chain liquidity and accessibility to users. This multi-chain strategy separates the veteran protocol among others that are mainly operating in single blockchain ecosystems.
It is unclear whether this revival will be sustainable, but the story of the dino coin about the first DeFi projects is becoming popular. To date, Synthetix is on the forefront of this new trend since legacy protocols have shown that they can still compete with newer entrants.
Gold price (XAU/USD) jumps to a fresh record high near $4,130 during the early Asian session on Tuesday. The precious metal extends the rally as renewed US-China trade tensions send investors flocking to safe-haven assets. The Federal Reserve’s (Fed) Chair Jerome Powell is scheduled to speak later on Tuesday.
Escalating trade tensions between the US and China reignited fears of a trade war between the world’s two largest economies, boosting safe-haven assets like the Gold price. US President Donald Trump announced on Friday that he will impose new trade measures against Beijing, including 100% tariffs on all Chinese goods and export controls on critical US-developed software, due to take effect by 1 November.
Nonetheless, Trump adopted a less strident stance on Sunday, saying that everything would be “fine” and that the US was not looking to “hurt” China.
Expectations mounted for further interest rate cuts by the US Fed, which contributes to Gold’s upside. Markets are currently pricing in an almost certain 25 basis points (bps) rate cut at the Fed’s October meeting, with another reduction expected in December, according to the CME FedWatch tool. Lower interest rates could reduce the opportunity cost of holding Gold, supporting the non-yielding precious metal.
Further consolidation or correction cannot be ruled out in the near term, as the yellow metal has climbed over 56% year-to-date so far this year. “Given the carousel of drivers, and how short-lived dips have been, this rally has legs in our view, but a near-term correction would be healthier for a longer-term uptrend,” said Suki Cooper, global head, commodities research at Standard Chartered Bank.
Gold FAQs
Gold has played a key role in human’s history as it has been widely used as a store of value and medium of exchange. Currently, apart from its shine and usage for jewelry, the precious metal is widely seen as a safe-haven asset, meaning that it is considered a good investment during turbulent times. Gold is also widely seen as a hedge against inflation and against depreciating currencies as it doesn’t rely on any specific issuer or government.
Central banks are the biggest Gold holders. In their aim to support their currencies in turbulent times, central banks tend to diversify their reserves and buy Gold to improve the perceived strength of the economy and the currency. High Gold reserves can be a source of trust for a country’s solvency. Central banks added 1,136 tonnes of Gold worth around $70 billion to their reserves in 2022, according to data from the World Gold Council. This is the highest yearly purchase since records began. Central banks from emerging economies such as China, India and Turkey are quickly increasing their Gold reserves.
Gold has an inverse correlation with the US Dollar and US Treasuries, which are both major reserve and safe-haven assets. When the Dollar depreciates, Gold tends to rise, enabling investors and central banks to diversify their assets in turbulent times. Gold is also inversely correlated with risk assets. A rally in the stock market tends to weaken Gold price, while sell-offs in riskier markets tend to favor the precious metal.
The price can move due to a wide range of factors. Geopolitical instability or fears of a deep recession can quickly make Gold price escalate due to its safe-haven status. As a yield-less asset, Gold tends to rise with lower interest rates, while higher cost of money usually weighs down on the yellow metal. Still, most moves depend on how the US Dollar (USD) behaves as the asset is priced in dollars (XAU/USD). A strong Dollar tends to keep the price of Gold controlled, whereas a weaker Dollar is likely to push Gold prices up.
The EURJPY pair resumed the bearish corrective attack in Friday’s trading, hitting some of the previously suggested targets, to form quick positive rebound to settle near 176.50, keeping the main bullish scenario that depends on the stability within the bullish channel’s levels that appears in the above image.
Note that the continuation of the contradiction between the main indicators that might force the price to provide more of the sideways trading, to keep waiting for breaching 177.05 to confirm its readiness to form new bullish attack by targeting the top at 177.80.
The expected trading range for today is between 175.90 and 177.05
Trend forecast: Fluctuated within the bullish trend
The leading meme coin plunged from $0.25 to below $0.10 on several exchanges during the panic-driven selloff before quickly rebounding to around $0.19.
At the time of writing, DOGE trades at $0.2126, marking a 12.12% daily recovery, with trading volume surging nearly 30%. Despite the volatility, analysts believe this correction mirrors the same type of price behavior that historically precedes explosive rallies.
A Familiar Pattern Before Major Moves
According to market analysts such as Daan Crypto Trades, the recent DOGE movement aligns closely with patterns observed before major bullish reversals.
Most charts look the same. Took $DOGE here as an example.
1. Sharp sell off Friday evening into the giant wicks. 2. Initial bounce usually topping about halfway through the entire move (which often went -70% or more). 3. Sideways chop 4. Another -10% to -20% sell off on most… pic.twitter.com/2tcpEGvYny
The asset’s sharp 70% plunge from peak to trough, followed by a swift 50% recovery, is similar to structures seen in previous breakout phases. Analysts expect a period of sideways trading and potential minor corrections before another upward push.
Ali Martinez, another prominent crypto analyst, identified the $0.19-$0.21 range as a critical support area that could serve as a “buy-the-dip” zone.
Martinez shared a chart, indicating inefficiencies and gaps between the bounce levels and pre-crash highs, which often act as magnet zones for future price recovery.
DOGE Price Analysis: Key Support Zone and Bullish Outlook
DOGE remains within a long-term ascending channel, suggesting that its broader uptrend is still intact. If the current recovery holds above $0.20 and gains momentum toward $0.30, analysts say history could be setting up for another explosive Dogecoin breakout, targeting $0.48.
The optimistic target on many technical charts still hovers around the symbolic $1 mark, a move that would represent a more than 370% rally from current prices.
Source: TradingView
Meanwhile, the RSI levels have stabilized near 42, indicating that the asset is out of the oversold zone, while the MACD shows early signs of a bullish crossover.
These indicators collectively hint at a potential reversal forming beneath the surface.
A Rally Brewing?
Dogecoin has bounced back from a brutal market crash, with analysts pointing out that its recent price structure closely resembles those seen before major rallies.
With key support holding near $0.20, traders are eyeing bullish targets ranging from $0.48 to $1 if the recovery continues, based on historical chart patterns.
DOGE $1 Dream – $MAXI Is Already Ahead
While Dogecoin is eyeing a monster rally, Maxi Doge ($MAXI) is attracting attention while blending the high-energy world of gym culture with the excitement of bullish crypto trading.
The project’s mascot, a muscular, caffeine-fueled Doge, captures the essence of its slogan: “never skip leg day, never skip a pump”.
For its holders, owning $MAXI is not merely an investment, but an entry into a lifestyle community that values both physical and financial growth.
The project’s ecosystem revolves around collective engagement, where holders share high-leverage trading strategies, compete on weekly leaderboards, and take part in themed challenges such as “Max Ripped, Max Gains”.
The presale has already raked in $3.5 million while currently, each $MAXI is priced $0.0002625.
Disclaimer: Coinspeaker is committed to providing unbiased and transparent reporting. This article aims to deliver accurate and timely information but should not be taken as financial or investment advice. Since market conditions can change rapidly, we encourage you to verify information on your own and consult with a professional before making any decisions based on this content.
A crypto journalist with over 5 years of experience in the industry, Parth has worked with major media outlets in the crypto and finance world, gathering experience and expertise in the space after surviving bear and bull markets over the years. Parth is also an author of 4 self-published books.
The 50-day average’s defense is a bullish signal, yet downside risks linger. Natural gas is caught in a short-term rising trend channel, contrasting with a broader declining channel. Recent highs stalled near the 200-day moving average at $3.38, aligning with the top of the falling channel, where resistance triggered a double top bearish reversal last Thursday. The rejection also coincided with the upper boundary of the rising channel, extended by 25%. A reversal from this level typically targets the channel’s lower boundary, a scenario still in play if today’s support falters.
Critical Support Zone at $2.95
Should the $3.03 low give way, a deeper support zone at $2.95 emerges as a key target. This level, projected for October 21, marks the intersection of the rising channel’s lower line and the falling quarter channel line of the larger bearish trend. Reinforcing its significance, a gap fill at $2.95 aligns with an anchored Volume Weighted Average Price (VWAP) at $2.98, rooted in the February 2024 lows. This convergence of technical markers makes $2.95 a high-probability floor if selling resumes.
Outlook and Key Levels
Today’s rally suggests buyers are defending $3.03, but the broader bearish channel keeps pressure on. A close above $3.09 strengthens the bullish case, while a break below $3.03 targets $2.95. Monitor today’s close for confirmation of support or renewed weakness—$3.38 resistance remains a hurdle for any sustained recovery.
For a look at all of today’s economic events, check out our economic calendar.
The Pound to Euro (GBP/EUR) exchange rate spent another week trapped below 1.15 as UK fiscal concerns offset Euro weakness tied to France’s deepening political impasse.
Foreign exchange strategists warn that, with Prime Minister Lecornu reappointed and budget gridlock unresolved, both currencies are likely to face lingering downside pressure.
GBP/EUR Forecasts: Groundhog Day for France
SocGen forecasts that the Pound to Euro (GBP/EUR) exchange rate will weaken to 1.11 by the third quarter of 2026 on Pound vulnerability.
Credit Agricole, however, is backing gains to 1.2050 by the end of next year as the French situation contributes to Euro losses.
GBP/EUR briefly hit 3-week highs around 1.1550 during the week on Euro concerns before a dip back below 1.15 amid a lack of confidence in underlying UK fundamentals with the Pound unable to benefit from a record high for the FTSE 100 index.
French Prime Minister Lecornu resigned on Monday, but after a week of intense political intrigue, President Macron renominated him on Friday.
Save on Your GBP/EUR Transfer
Get better rates and lower fees on your next international money transfer.
Compare TorFX with top UK banks in seconds and see how much you could save.
There is no evidence that Lecornu can fare better this time around and faces major difficulties in passing the budget with the on-going risk that deadlock will eventually lead to fresh elections.
SocGen does note the potential for short-term Euro weakness; “The French political situation is clearly another source of concern, with policy paralysis potentially dampening growth expectations. The bond market has to digest supply, and higher French yields create headlines. Even if yield differentials are far below those we saw for peripheral bonds in 2010-2015, this all weighs on the euro.”
Credit Agricole also notes near-term Euro vulnerability; “The economic outlook of the Eurozone’s largest economy has been attracting considerable attention. In all, we think that economic uncertainty and lingering political risks in France could keep the EUR on the defensive in the very near term.”
SocGen expects weak UK growth and that Bank of England will eventually relent; “The stickiness of inflation relative to the euro zone and the US is limiting the room for manoeuvre by the BoE so decreasing the level of policy restriction to boost growth must wait. SG economics postponed the next rate cut from November to February but maintain the terminal forecast of 3.0%.”
JP Morgan noted cracks in the UK economic outlook; “With last week’s UK PMI suggesting political uncertainty is starting to creep back into the UK data, this emphasizes the negative growth-fiscal feedback loop where weaker UK growth worsens the fiscal hole which holds long-end gilt yields higher than they otherwise would be and that triggers the stagflationary reaction function in the currency.”
HSBC expects further fiscal fears; “In the UK, it seems more like mission impossible – particularly for fiscal policy. We estimate the UK Chancellor may need to find around GBP30bn of additional consolidation at the 26 November Budget – a big ‘black hole’ to fill.”
It added; “Tax rises and spending cuts will not go down well with voters and her own party. But a non-credible plan – such as assuming unrealistic tax rises and spending cuts in four or five years’ time – or even a small tweak to the fiscal targets to allow more borrowing, could alarm the bond market.”
Like this piece? Please share with your friends and colleagues:
International Money Transfer? Ask our resident FX expert a money transfer question or try John’s new, free, no-obligation personal service! ,where he helps every step of the way,
ensuring you get the best exchange rates on your currency requirements.
Explore how vitamin B12 supports the brain and nervous system, why deficiencies persist even in well-nourished populations, and what new research reveals about improving diagnosis and dietary strategies.
Image Credit: Tatjana Baibkova / Shutterstock.com
Introduction
Vitamin B12 is essential for red blood cell formation, neurological function, and DNA synthesis, yet deficiencies remain common due to poor absorption or limited dietary intake. This article examines natural sources, health benefits, and current research gaps in vitamin B12 metabolism and brain health.1,3,4.
What is vitamin B12?
Methylcobalamin, one form of vitamin B12, supports methionine synthase in converting homocysteine to methionine. This process is vital for creating S-adenosylmethionine (SAMe), a universal methyl donor for DNA, proteins, and neurotransmitters.1,3
In its 5-deoxyadenosylcobalamin form, vitamin B12 acts as a cofactor for L-methylmalonyl-CoA mutase, critical for metabolizing fatty acids and amino acids to support energy production and hemoglobin synthesis.The L-methylmalonyl-CoA mutase pathway contributes to the development and maintenance of the myelin sheath that insulates nerves, with even minor myelin deficiencies leading to neurological symptoms.3,4
Because vitamin B12 is almost exclusively found in animal-based products, vegetarians and vegans are more susceptible to deficiency without dietary fortification or supplementation.Plant foods do not naturally contain vitamin B12; fortified foods and supplements provide bioavailable sources for those avoiding animal products.Deficiency increases the risk of megaloblastic anemia, characterized by impaired DNA synthesis and macrocytosis, as well as severe, sometimes irreversible, neurological damage.1,2,3,4
Best natural food sources of vitamin B12
Synthesized by microorganisms, vitamin B12 is accumulated in animals and animal-derived products.1,4
Organ meats and shellfish are the richest dietary sources, with a 3-ounce (85 g) serving of cooked clams providing approximately84.1 µg, while beef liver contains about 70.7 µg.1 Fatty fish, such as trout and salmon, supply 5.4 µg and 4.8 µg per 3-ounce serving, respectively.1
Fortified nutritional yeasts can contain up to 24 µg vitamin B12 per 50 g serving, and fortified cereals up to 6 µg per portion. For vegetarians (but not vegans), dairy products provide meaningful amounts: one cup (240 mL) of low-fat milk offers 1.2 µg, and one ounce (28 g) of Swiss cheese provides 0.9 µg.1
Once ingested, vitamin B12 absorption requires gastric acid and intrinsic factor. In food, B12 first binds to haptocorrin in saliva and gastric fluid, is released by pancreatic enzymes in the duodenum, then complexes with intrinsic factor for receptor-mediated absorption in the distal ileum.1,3 This process is often impaired in older adults due to atrophic gastritis, increasing deficiency risk even when intake meets dietary recommendations.4
Recent research indicates that vitamin B12 exhibits source-specific bioavailability: B12 from dairy products is roughly three times more bioavailable than that from meat, fish, or poultry, making dairy an especially efficient source.1
Image Credit: GoodStudio / Shutterstock.com
Vitamin B12 Content of Selected Foods
Food
Micrograms (µg) per serving
Percent Daily Value (DV)*
Beef liver, cooked, pan fried, 3 ounces
70.7
2,944
Clams (without shells), cooked, 3 ounces
84.1
3,504
Oysters, eastern, wild, cooked, 3 ounces
14.9
621
Nutritional yeast, fortified, from several brands (check label), about ¼ cup
8.3 to 24
346 to 1,000
Salmon, Atlantic, cooked, 3 ounces
2.6
108
Tuna, light, canned in water, 3 ounces
2.5
104
Beef, ground, 85% lean meat/15% fat, pan browned, 3 ounces
2.4
100
Milk, 2% milkfat, 1 cup
1.3
54
Yogurt, plain, fat free, 6-ounce container
1.0
43
Breakfast cereals, fortified with 25% of the DV for vitamin B12, 1 serving
0.6
25
Cheese, cheddar, 1½ ounces
0.5
19
Egg, whole, cooked, 1 large
0.5
19
Turkey, breast meat, roasted, 3 ounces
0.3
14
Tempeh, 1/2 cup
0.1
3
What does %DV mean for vitamin B12? % Daily Value (%DV) shows how much vitamin B12 a serving of food provides toward the 2.4 µg daily goal for adults. For example, if a food has 25% DV B12, one serving provides about one quarter of your daily B12 needs.
Health benefits of vitamin B12
Vitamin B12 deficiency can cause peripheral neuropathy and cognitive impairment due to its critical role in maintaining nervous system integrity.3 Therapeutic replacement in overt deficiency is standard of care, and in diabetic peripheral neuropathy, supplementation improves symptom and pain scores though objective neurophysiologic measures may not consistently change.5,6
Deficiency also disrupts red blood cell maturation, leading to megaloblastic anemia accompanied by fatigue and weakness.3
Although low vitamin B12 levels are often linked to depression, a 2021 meta-analysis of randomized trials in individuals without advanced neurological disorders found no significant effect of supplementation on depressive symptoms or overall cognition; observational associations with cognitive decline remain mixed.7,8
Recommended intake and deficiency risks
The U.S. National Institutes of Health (NIH) recommends 2.4 µg vitamin B12 daily as the Recommended Dietary Allowance (RDA) for adults.This increases to 2.6 µg during pregnancy and 2.8 µg during lactation to account for fetal development and milk production.1
Because the liver stores substantial amounts of vitamin B12, deficiency may take years to appear.Early warning signs include fatigue, weakness, paresthesia, balance problems, memory loss, and depression.1
High-risk groups requiring regular monitoring include vegans and vegetarians, older adults with reduced absorption, individuals with pernicious anemia or gastrointestinal disorders, and those using medications such as metformin and proton pump inhibitors.1,2,3
5 Signs and Symptoms of Vitamin B12 Deficiency
Safety and excess intake
As a water-soluble vitamin, excess vitamin B12 is usually excreted in urine. No Tolerable Upper Intake Level (UL) has been established, and B12-related toxicity is not regarded as a clinical concern.1
Some studies have reported a possible, though inconclusive, association between very high serum vitamin B12 levels and certain chronic health outcomes, emphasizing adherence to RDA values unless higher doses are medically indicated.2
Present limitations and research gaps
Despite decades of study, challenges remain in assessing vitamin B12 status. Serum measurements may not accurately represent intracellular levels, while markers such as methylmalonic acid (MMA) and homocysteine, though sensitive, lack specificity, especially in older adults and those with renal impairment.1
A recent study found that older adults with low-normal vitamin B12 concentrations exhibited slower visual-evoked potentials, age-dependent processing-speed deficits, and increased white-matter hyperintensity volumes compared with those having high-normal levels. Conversely, elevated levels of the biologically inactive holo-haptocorrin fraction correlated with serum Tau, a biomarker of neurodegeneration.These findings suggest that subclinical neurological effects may occur at higher thresholds than the current anemia-based definition of deficiency, warranting reassessment of diagnostic cutoffs.1–4,9
Conclusions
Vitamin B12 occurs mainly in animal-derived foods, emphasizing the need for dietary awareness among individuals consuming plant-based diets or those with impaired absorption.
Given the risk of irreversible neurological damage and the limitations of current diagnostic methods, increased clinical vigilance for at-risk populations is essential. Future research should refine deficiency definitions and develop more sensitive diagnostic tools to detect early, subclinical vitamin B12 insufficiency, particularly in aging populations.
Ankar, A., & Kumar, A. (10 September 2024). Vitamin B12 deficiency. In StatPearls [Internet]. StatPearls Publishing.https://www.ncbi.nlm.nih.gov/books/NBK441923/. Accessed 22 September 2025
Markun, S., Gravestock, I., Jäger, L., et al. (2021). Effects of Vitamin B12 Supplementation on Cognitive Function, Depressive Symptoms, and Fatigue: A Systematic Review, Meta-Analysis, and Meta-Regression. Nutrients13(3); 923. DOI:10.3390/nu13030923, https://www.mdpi.com/2072-6643/13/3/923.
Zhang, C., Luo, J., Yuan, C., & Ding, D. (2020). Vitamin B12, B6, or Folate and Cognitive Function in Community-Dwelling Older Adults: A Systematic Review and Meta-Analysis. Journal of Alzheimer’s Disease77(2); 781-794. DOI:10.3233/jad-200534, https://content.iospress.com/articles/journal-of-alzheimers-disease/jad200534.
Beaudry‐Richard, A., Abdelhak, A., Saloner, R., et al. (2025). Vitamin B12 Levels Association with Functional and Structural Biomarkers of Central Nervous System Injury in Older Adults. Annals of Neurology97(6); 1190-1204. DOI:10.1002/ana.27200, https://onlinelibrary.wiley.com/doi/10.1002/ana.27200.
The Cardano price action has been at an interesting stage despite continuing to trade far below its all-time high of $3.10, set in 2021. Yet, technical formations now indicate a possible reversal phase may be approaching, which may far surpass this ATH.
A symmetrical triangle pattern has been formed by converging rising lows and descending highs of last one year that has unmistakably taken shape on the ADA price chart, reflecting an extended period of compression.
Historically, such formations often precede sharp volatility spikes, and in Cardano’s case, the longer the consolidation, the greater the potential upside move would be in play.
In recent trading sessions, the ADA price today managed to gain nearly 18%, bouncing off the crucial $0.69 support level. This price zone now serves as a pivotal base for any upcoming bullish action. If ADA continues to hold this floor, the first upside target lies near $0.95, with higher levels like $1.15 and $1.35 emerging as critical resistance points to watch before year completion.
Critical Levels Define Cardano’s Path Ahead
For now, the Cardano price USD must maintain support at $0.69 more than ever to preserve the bullish setup. This is because a sustained strength here on from above this level could confirm the triangle breakout and odds suggest that ADA might push toward the $1.15-$1.35 resistance zone, before year-end if market sentiment turns positive.
But, if momentum carries ADA price action over into 2026, projections suggest that ADA could climb as high as $1.90 or even $2, which would represent more than a 210% increase from what the current levels are when writing. However, a breakdown below $0.66-$0.69 would invalidate this bullish formation and shift focus toward lower supports areas.
The coming weeks will therefore be pivotal for ADA, as whether the ADA crypto can convert its year-long compression into an explosive uptrend.
Elliott Wave Outlook Strengthens the Bullish Case
Adding depth to the bullish narrative, an early October X post reinforced optimism with an bullish ADA price forecast that aligns with Elliott Wave theory.
The chart mapped ADA’s journey through previous market cycles, labeling 2024’s election rally as Wave 1 and 2025’s sideways movement as Wave 2 as an accumulation phase that is waiting for a powerful expansion move.
According to this wave structure, the upcoming Wave 3 is projected to drive ADA toward the $3.37 mark, typically considered the strongest phase of a bullish cycle.
The extended consolidation period seen in 2025 strengthens this theory, suggesting that ADA has been quietly building momentum beneath the surface.
Recent liquidation events may have served as a “shakeout,” removing short-term traders and clearing the path for longer-term holders to accumulate positions before a breakout.
Cardano’s price prediction suggests a potential rise to $1.90 or even $2.00 by 2026 if it successfully breaks out from its current long-term consolidation pattern.
Is Cardano a good investment?
Cardano shows a promising technical setup after a long consolidation, suggesting significant potential upside if it holds key support levels, though all crypto carries risk.
