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23 12, 2025

Ultra-premium matcha, koji rice mold star in Starbucks Japanese New Year’s Frappuccino and drinks

By |2025-12-23T17:04:48+02:00December 23, 2025|Dietary Supplements News, News|0 Comments


Starbucks Japan closes out the year with luxurious and innovative dessert drinks for the most Japanese holiday season of the year.

Unlike some other countries in Asia, Japan doesn’t really celebrate the lunar New Year. Instead, Japan follows the same custom as most of the western world, with New Year’s Eve celebrations on December 31, and the first three days of the January traditionally considered the New Year’s season.

However, in Japan New Year’s, or Oshogatsu, as it’s called in Japanese, is still a very, very Japanese celebration. While things are pretty western/internationalized at Christmas, Oshogatsu decorations lean very much into traditional Japanese imagery, with auspicious motifs like Mt. Fuji, folding fans, and cranes adorning New Year’s cards, stores and shopping streets playing koto music, and people dressing in kimono for their first shrine or temple visit of the New Year.

So in keeping with that, later this month Starbucks Japan is releasing a very, very Japanese-tasting Frappuccino as 2025 winds down.

Not only is the final Frappuccino for the year a green tea one, it goes beyond just plain old mathca with the inclusion of gyokuro. Gyokuro is a premium grade of matcha, made from leaves grown under shades to protect them from the harshening effects of strong sunlight in the weeks before they’re picked, leading to a deeper flavor with a subtle sweetness, a more robust aroma, and a vibrant green color. Harvested just once a year in late spring. less than one percent of the tea grown in Japan is gyokuro, and as such it commands high prices.

Starbucks Japan’s new Gyokuro Matcha Frappuccino has a base of gyokuro-enhanced matcha, and at the bottom of the glass, waiting for you to stir it in, is a large dollop of smooth matcha an (sweet bean paste). The topping is green tea-flavored too, matcha whipped cream sprinkled with crisp bits of crumbled matcha feuilletine crepe.

Joining the Gyokuro Matcha Frappuccino on the Starbucks menu will be a Gyokuro Matcha Latte (shown on the left in the photo above), a mixture of gyokuro and steamed milk that also gets matcha whipped cream and feuilletine, but does without the matcha an.

Starbucks has one more special Oshogatsu beverage on the way, and while it doesn’t have any gyokuro or matcha in it, it’s got another unique ingredient that’s also undeniably Japanese: koji.

The Honey Ginger Rice Koji Latte makes use of Starbucks’ newest plant-based milk, made from Japanese-grown rice koji. What’s koji? It’s a kind of mold that triggers fermentation in rice, but don’t run away/wretch just yet! Koji is harmless, and it’s actually one of the key ingredients in making sake. Starbucks has also figured out how to use it to make a dairy substitute, and the Honey Ginger Rice Koji Milk Latte is a combination of rice koji milk, made from domestically grown Japanese rice, and blond espresso, with a whipped cream swirl on top sprinkled with pieces of honey-treated ginger. The result, Starbucks says, is a drink with a gentle yet comfortingly sweetness, and also one that’s perfect for sipping on in cold winter weather, as ginger is traditionally thought to have a warming effect on the body in Japan.

The Gyokuro Matcha Frappuccino and Gyokuro Matcha Latte will be offered in tall sizes only, priced at 700 yen (US$4.60) and 650 yen, respectively. The Honey Ginger Rice Koji Milk Latte is also 650 yen for a tall, but can also be had as a short size for 610 yen.

All three beverages go on sale December 26 and will be available for a limited, unspecified time, but there’ll be at least some availability overlap with Starbucks collaboration with a 166-year-old Kyoto doll maker.

Source, images: Starbucks Japan
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23 12, 2025

Can psychobiotics help with depression, stress and anxiety?

By |2025-12-23T15:03:34+02:00December 23, 2025|Dietary Supplements News, News|0 Comments


Long live bacteria!

You’ve surely heard of probiotics, which can help maintain a healthy gut for better digestion, nutrient absorption and immune support.

But a budding class of probiotics called “psychobiotics” is being touted for mental health benefits, too, with promises of improving mood, cognition and anxiety — without medication.

Psychobiotics are a type of probiotics that seem to have mental health benefits. Jack Forbes / NY Post Design

On TikTok and Instagram, dozens of content creators hawk different “natural” brands, raving that the supplements have helped them with everything from mood swings to depression to panic attacks.

“[They] helped me get over crying spells, anxiousness, rage and become more resilient to my daily challenges,” said one.

“I didn’t want to feel angry anymore. I didn’t want to be irritated when my daughter would cry … I made a simple shift in my wellness routine that started working the first week I used it,” wrote another.

But do they really work on stress and depression? The Post spoke with several experts about the latest nutritional craze and if it’s worth joining this cultured club.

What are psychobiotics?

Researchers John Cryan and Ted Dinan introduced the term in 2013, describing them as live organisms that, “when ingested in adequate amounts, [produce] a health benefit in patients suffering from psychiatric illness.” 

The definition was later broadened to classify them not only as probiotics but also as prebiotics, which support the growth of good gut bacteria.

Examples of psychobiotics include certain strains of Lactobacillus plantarum, which research suggests may help ease stress, anxiety, depression and insomnia. Certain strains of Bifidobacterium longum, too, have been shown to improve mood, in part by lowering the stress hormone cortisol and modulating brain activity.

The number of probiotic strains with solid evidence of mental health benefits has increased “remarkably” in the last five years, neuroscientist Dr. Jane Foster, PhD, a professor at UT Southwestern Medical School’s Department of Psychiatry, told The Post. 

Research has shown psychobiotics may improve stress, anxiety, depression and insomnia. Michelle – stock.adobe.com

How do psychobiotics work?

While it’s not 100% clear how they improve mental health, we know that they “act through the gut bacteria to influence the brain,” said Foster, who studies the link between the microbiome and mental illness.

By positively affecting the gut-brain axis, psychobiotics can reduce inflammation and regulate the release of stress hormones.

These probiotics can also help produce “feel-good” neurotransmitters including dopamine, serotonin and GABA through the gut-brain axis. The nuts and bolts of these mechanisms are still being explored.

What does the science say?

“It’s so attractive to say, ‘Oh, the serotonin from your gut is released by [the] gut microbiome and influences our brain,” gastroenterologist Dr. David Levinthal, director of UPMC’s Neurogastroenterology & Motility Center, told The Post. “And rather than taking Prozac, you have to just tweak your gut microbiome.”

But, he added, “I don’t think it’s that simple.”

People might report feeling better after taking these supplements, but those observations are difficult to confirm in clinical trials.

Though the studies are small, emerging research has found that psychobiotics may alleviate stress, anxiety and depression.

And certain strains stand out. Taken together, Lactobacillus helveticus R0052 and Bifidobacterium longum R0175 have shown mixed, but some positive, results for depression symptoms. 

The number of probiotic strains with solid evidence of mental health benefits has increased “remarkably” in the last five years, neuroscientist Dr. Jane Foster, PhD, a professor at UT Southwestern Medical School’s Department of Psychiatry, told The Post.  PheelingsMedia – stock.adobe.com

Depression and anxiety improved after just two weeks in mildly or moderately depressed people who took a combo of Lactiplantibacillus plantarum HEAL9 and the compound SAMe. 

Additional L. plantarum strains (like DR7 and P8) seemed to lower anxiety and stress. Bifidobacterium breve CCFM1025 shows promise for depression and Bifidobacterium longum 1714 for stress.

Before you head to the pharmacy, you should consult with your doctor.

Many questions remain unanswered, like: What are the most effective psychobiotic strains? Who should take them, and how much should they take?

“[Doctors] have to be incredibly cautious about recommending this for patients because the evidence is still being worked out,” Levinthal said.

Can you mimic the effects of psychobiotics in food?

If your goal is to find food with the exact strains that you’d get in pill form, that’s going to be a hard task, Levinthal said.

Still, adopting a “psychobiotic diet” could help your mental health. One study had a small group of healthy adult volunteers eat prebiotic and fermented foods “known to benefit the microbiota composition” for four weeks.

These foods include whole grains, legumes, fermented fare like kefir, kombucha and yogurt, plus fruits and vegetables high in prebiotic fiber. The “psychobiotic dieters” reported lower stress the more they followed the diet. 

Changing what you consume, whether you call it a “psychobiotic diet” or not, could be worth a shot.

Dr. Drew Ramsey, a nutritional psychiatrist, suggests eating probiotic- and prebiotic-rich food such as sauerkraut, fermented veggies, sourdough, kefir, miso and leafy greens. 

“Until science proves otherwise, that probiotic pills are superior to fermented foods, I think it’s a safer, more sustainable, more economical recommendation to encourage people to increase their plant intake and to explore more fermented foods in their diet,” Ramsey, author of “Eat to Beat Depression and Anxiety,” told The Post. 

Research also indicates that following a Mediterranean diet can significantly reduce depressive symptoms.

While it’s not 100% clear how they improve mental health, we know that they act through the gut bacteria to influence the brain. master1305 – stock.adobe.com

What should I know before I try psychobiotics?

Though probiotics are generally pretty low risk, supplements don’t face the same rigorous standards as medicines. 

“The regulation of supplements [or lack thereof] is a completely different ballgame than FDA-approved,” Levinthal noted. “You can make a lot of claims and don’t have to substantiate them.”

So, if you’re struggling with your mental health, don’t confuse the promising benefits of psychobiotics with FDA-approved SSRIs, for example.

If you’re on antidepressants, you shouldn’t quit them cold turkey for psychobiotics. But you may want to talk with your doctor about adding them to your treatment plan, as studies suggest that probiotics can complement antidepressants. 

Interested in trying a probiotic for mental health? Foster suggests looking at the Alliance for Education on Probiotics’ guide, which evaluates on-the-market supplements backed by research. 

Potency matters too. Levinthal suggests looking for dosing info on the bottle around 1 × 109 colony-forming units — and check for the CFU count listed for the end of the product’s shelf life, as live probiotics can die over time. 

“Some people want a very natural approach [to mental health], and I think that’s reasonable,” Levinthal said. Psychobiotics as a concept is intriguing, he admitted. “It’s just that we need more data. If we have this interview five years from now, I might say something different.”



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23 12, 2025

Global matcha boom pushes Korean green tea exports to record high

By |2025-12-23T11:01:04+02:00December 23, 2025|Dietary Supplements News, News|0 Comments


Hollys Coffee goes to Japan as Korean franchises turn gaze abroad


A Hollys Coffee outlet in Seoul

Hollys Coffee, a unit of South Korea’s KG Group, is opening its first overseas outlet in Osaka, Japan, riding on the popularity of Korean culture, known as Hallyu or the K-wave, in the neighboring country.Hollys said on Monday it will open a coffee house at





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23 12, 2025

Beauty Supplements Market Size, Share

By |2025-12-23T09:00:34+02:00December 23, 2025|Dietary Supplements News, News|0 Comments


Report Overview

The Global Beauty Supplements Market size is expected to be worth around USD 8.3 Billion by 2034, from USD 3.2 Billion in 2024, growing at a CAGR of 10.0% during the forecast period from 2025 to 2034. In 2024 North America held a dominant market position, capturing more than a 39.4% share, holding USD 1.2 Billion in revenue.

Beauty supplements sit at the intersection of nutrition, functional foods, and personal care—using ingestible formats like capsules, gummies, powders, and ready-to-mix sachets to support visible outcomes such as skin hydration, hair strength, and nail quality. The category’s “industrial story” is less about cosmetics counters and more about food-grade ingredient processing, compliant labeling, and a fast-moving contract manufacturing ecosystem.

  • In the United States alone, FDA notes the dietary supplement market was worth more than $40 billion (2019), and the number of products expanded from about 4,000 (1994) to an estimated 50,000 to more than 80,000 (2019)—supported by a global supply chain that includes more than 10,000 facilities.

Beauty Supplements Market Size, Share

From an industrial scenario perspective, the category benefits from being built on the same manufacturing, ingredient, and regulatory backbone as the broader dietary supplement ecosystem—contract manufacturers, premix blenders, flavor houses, and testing labs—while borrowing branding and claim frameworks from beauty and functional foods. In the U.S., the dietary supplement industry’s overall economic impact in 2023 was $159 billion, supporting more than 615,000 jobs and generating $6.76 billion in state/local taxes and $10.7 billion in federal taxes.

Regulation and safety expectations are also shaping the industry’s direction. Codex has long provided global guidance for vitamin and mineral food supplements (CXG 55-2005), which supports harmonized approaches to quality and labeling. In the EU, nutrition and health claims for foods—including many supplement communications—are governed under Regulation (EC) No 1924/2006, pushing companies toward clearer substantiation and compliant wording. In India, FSSAI’s framework for health supplements and nutraceuticals similarly reinforces category definitions and compliance expectations.

Government and trusted regulatory frameworks are also shaping how the industry scales. In the U.S., companies introducing a new dietary ingredient must submit a premarket safety notification to FDA at least 75 days before marketing, which nudges innovation toward better-documented ingredients and cleaner dossiers.

The EU maintains a harmonized framework for food supplements through Directive 2002/46/EC, influencing permitted vitamin/mineral forms and labelling expectations across member states. In India, FSSAI has issued directives tied to the nutraceutical/health supplement framework (including 2022 directions), pushing clearer category definitions and compliance discipline in a fast-growing market.

Key Takeaways

  • Beauty Supplements Market size is expected to be worth around USD 8.3 Billion by 2034, from USD 3.2 Billion in 2024, growing at a CAGR of 10.0%.
  • Collagen Supplement held a dominant market position, capturing more than a 39.4% share.
  • Tablets & Capsules held a dominant market position, capturing more than a 39.2% share.
  • Skin Care held a dominant market position, capturing more than a 56.8% share.
  • Online held a dominant market position, capturing more than a 38.9% share.
  • North America emerged as the dominant region in the beauty supplements market, capturing 39.40% of global share and generating approximately US$1.2 billion.

By Type of Supplement Analysis

Collagen supplements lead with a 39.4% share, driven by strong demand for skin and hair health benefits.

In 2024, Collagen Supplement held a dominant market position, capturing more than a 39.4% share. This leadership was mainly supported by rising consumer focus on skin elasticity, anti-aging benefits, and overall beauty from within. Collagen supplements were widely used for improving skin firmness, reducing fine lines, and supporting hair and nail strength, making them a preferred choice among beauty-focused consumers. The segment also benefited from growing awareness of age-related collagen loss and the easy availability of collagen in powders, capsules, and ready-to-drink formats.

In 2025, demand remained stable as collagen supplements continued to be positioned as a daily wellness product rather than a short-term beauty solution. Strong adoption among working adults and aging populations further supported steady consumption. The segment’s dominance was reinforced by its compatibility with clean-label trends and routine beauty regimes, helping collagen supplements maintain a leading position within the beauty supplements market.

By Form Analysis

Tablets & capsules dominate with a 39.2% share, supported by ease of use and precise dosing.

In 2024, Tablets & Capsules held a dominant market position, capturing more than a 39.2% share. This strong position was mainly driven by consumer preference for convenient, easy-to-consume formats that fit well into daily routines. Tablets and capsules offered accurate dosage, longer shelf life, and better stability compared to liquid or powder forms, making them widely accepted across age groups. These formats were especially popular among working professionals and regular supplement users who value portability and consistency.

In 2025, demand remained steady as tablets and capsules continued to be trusted for delivering beauty nutrients such as collagen, vitamins, and antioxidants in a controlled manner. Their widespread availability through pharmacies and online channels further supported adoption. The segment’s leadership was reinforced by its cost efficiency, standardized formulations, and familiarity, allowing tablets and capsules to remain the preferred form in the beauty supplements market.

By Application Analysis

Skin care leads the market with a 56.8% share, driven by rising beauty awareness and daily wellness habits.

In 2024, Skin Care held a dominant market position, capturing more than a 56.8% share. This leadership was supported by strong consumer focus on maintaining healthy, youthful, and glowing skin through internal nutrition. Beauty supplements for skin care were widely used to support hydration, elasticity, and protection against early aging, making them a regular part of personal care routines. Growing awareness about the link between nutrition and skin health encouraged consistent usage across both younger and aging populations.

In 2025, demand continued as consumers increasingly preferred preventive skin care solutions rather than corrective treatments. Daily intake of skin-focused supplements became common due to changing lifestyles, higher stress levels, and environmental exposure. Easy availability and routine-based consumption further strengthened adoption. As skin appearance remained a key beauty priority, the skin care application continued to dominate the beauty supplements market with sustained consumer trust and usage.

By Distribution Channel Analysis

Online channels lead with a 38.9% share, supported by easy access and growing digital buying habits.

In 2024, Online held a dominant market position, capturing more than a 38.9% share. This dominance was driven by the convenience of home delivery, wider product choice, and easy access to detailed product information. Consumers increasingly preferred online platforms to compare ingredients, read reviews, and choose beauty supplements that match personal needs. Subscription models and regular discounts further supported repeat purchases.

In 2025, online sales continued to grow as digital payment adoption and mobile shopping became more common. Social media promotion and influencer recommendations also played an important role in guiding purchase decisions. As trust in e-commerce platforms improved and delivery networks expanded, online channels remained the preferred distribution route for beauty supplements, supporting steady market growth.

Beauty Supplements Market ShareBeauty Supplements Market Share

Key Market Segments

By Type of Supplement

  • Collagen Supplement
  • Vitamins & Minerals
  • Omega-3 Fatty Acids
  • Antioxidants
  • Probiotics
  • Others

By Form

  • Tablets & Capsules
  • Powder
  • Liquid
  • Gummies & Chews
  • Others

By Application

  • Skin Care
  • Hair Care
  • Nail Care
  • Others

By Distribution Channel

  • Supermarkets/Hypermarkets
  • Pharmacies/Drugstores
  • Specialty Stores
  • Online
  • Others

Emerging Trends

Prebiotics, Adaptogens, and Sleep Support Enter Beauty Supplements

One of the latest trends in beauty supplements is the shift from single “beauty hero” ingredients to whole-body routines built around the gut–skin connection and everyday stress. The idea is practical: if digestion is off, sleep is poor, and stress is high, skin often looks tired and reactive—so brands are blending beauty goals with microbiome support, calming botanicals, and sleep-friendly stacks.

You can see this trend clearly in recent industry tracking from the Council for Responsible Nutrition (CRN). In its 2024 survey update, CRN reported that prebiotic use rose to 7% of supplement users in 2024, up from 5% in 2023. In the same survey release, ashwagandha reached 8% of supplement users in 2024, up from 2% in 2020. Melatonin use also remained elevated at 16% of supplement users.

CRN’s same update also highlights who is pushing this trend: it notes that women—especially younger women—are more likely than men to say they take supplements to enhance skin, hair, and nail health. That matters because younger buyers are also the ones most open to routine-stacking. Even spending is holding steady, which supports repeat buying: the median monthly spend among supplement users was $50 in 2024, while those buying from healthcare professionals reported a median monthly outlay of $100.

Regulatory and government guidance is shaping how this trend is communicated. In the U.S., FDA explains that structure/function claims on supplements are not pre-approved, but manufacturers must have substantiation that claims are truthful and not misleading, must submit a notification to FDA within 30 days after marketing, and must include the required disclaimer that FDA has not evaluated the claim. This pushes brands to be more careful with wording—so you see more “supports skin hydration,” “supports the skin barrier,” or “supports stress response,” instead of bold cure-like promises.

Drivers

Rising Everyday Supplement Use Is Pulling Beauty Supplements Into the Mainstream

One major driving factor for beauty supplements is simple: more people are already taking supplements as part of daily life, so “beauty-from-within” products feel like a natural add-on rather than a new habit. In the U.S., national health data shows that 57.6% of adults aged 20+ used at least one dietary supplement in the past 30 days (2017–2018). Usage is higher among women at 63.8%, compared with 50.8% among men. That matters because women are also the most consistent buyers of skin, hair, and nail solutions—so the base audience is already there, already familiar with capsules, powders, and gummies.

One major driving factor for beauty supplements is simple: more people are already taking supplements as part of daily life, so “beauty-from-within” products feel like a natural add-on rather than a new habit. In the U.S., national health data shows that 57.6% of adults aged 20+ used at least one dietary supplement in the past 30 days (2017–2018). Usage is higher among women at 63.8%, compared with 50.8% among men. That matters because women are also the most consistent buyers of skin, hair, and nail solutions—so the base audience is already there, already familiar with capsules, powders, and gummies.

Regulation and government-led oversight also supports this growth by pushing clearer rules and safer innovation, which builds consumer confidence over time. For example, in the U.S., a company that wants to market a new dietary ingredient generally must submit a premarket safety notification to the FDA at least 75 days before introducing it into interstate commerce. That encourages better documentation and slows down “wild” ingredient launches—important in a category where consumers expect both beauty results and safety.

In Europe, food supplement rules are anchored by Directive 2002/46/EC, which sets a structured framework around vitamins and minerals used in supplements and helps align expectations on labelling and composition. This kind of clarity supports wider retail distribution because retailers and brands can build products with fewer compliance surprises across markets.

Restraints

Safety & Regulation Challenges Restricting Growth of Beauty Supplements

One major restraining factor for beauty supplements is the ongoing concern about safety, effectiveness, and regulation of these products, which makes many consumers hesitant to buy or continue using them. Unlike conventional medicines, dietary supplements—including those positioned for skin, hair, and nail benefits—are not reviewed by regulators for safety or effectiveness before they come to market. In the United States, for example, the U.S. Food and Drug Administration (FDA) does not have the authority to approve dietary supplements for safety or effectiveness before they are sold to the public. That means companies can launch beauty supplement products without proving they actually work or are safe for everyone.

This regulatory gap contributes to a broader lack of consumer confidence. People who are thoughtful about their health often look for evidence-based results, but many beauty supplements lack strong clinical data showing they deliver the promised benefits. Even government-sponsored health resources like the National Institutes of Health Office of Dietary Supplements emphasize that supplements cannot replace a healthy, varied diet and that many products “need more study to determine if they have value.”

Another part of the problem is that regulatory systems do not require detailed ingredient verification or quality checks before products are sold. A U.S. Government Accountability Office review from 2008–2011 found 6,307 reports of health problems tied to dietary supplements, including issues like contamination and mislabeling. Some products had heavy metals or incorrect ingredient amounts listed on their labels—situations that can easily erode trust in the entire category.

At the policy level, this regulatory restraint is rooted in the Dietary Supplement Health and Education Act of 1994 (DSHEA), which allows products to be sold without pre-market safety or efficacy evaluation. Critics of DSHEA point out that this law means regulators can only act after a problem is identified, rather than preventing issues before they arise. While companies appreciate the flexibility it gives them, many healthcare professionals and public health advocates say it leaves consumers to navigate safety and effectiveness questions on their own.

Opportunity

Clinical-Backed, Personalized “Beauty-From-Within” Products Are the Biggest Growth Opportunity

A major growth opportunity for beauty supplements is to move from “pretty promises” to measurable, science-backed results—and then package those results into routines people can actually follow. The customer base is already huge. In the U.S., government health data shows 57.6% of adults (age 20+) used at least one dietary supplement in the past 30 days (2017–2018). Women reported higher use (63.8%) than men (50.8%). That’s a strong signal that the habit is mainstream, especially among the core audience for skin, hair, and nail benefits.

Regulatory structure is another reason this opportunity is real. In the U.S., if a company wants to market a supplement with a new dietary ingredient, it must submit a safety notification to FDA at least 75 days before the ingredient is introduced into interstate commerce. This pushes serious companies toward better safety files and tighter quality systems—exactly the kind of discipline that helps beauty supplements gain long-term trust.

In Europe, food supplements are anchored by Directive 2002/46/EC, which sets a clear framework (especially around vitamins and minerals used in supplements). That kind of rulebook supports cross-border scaling, retailer confidence, and more consistent product standards—helpful when you’re trying to build a repeat-purchase category like collagen, beauty gummies, or “skin barrier support” blends.

Large food and nutrition groups are already putting real weight behind the broader “health science” platform, which can spill over into beauty supplement innovation and distribution. Nestlé’s Health Science business reported CHF 5.0 billion in sales in 2024, showing how scaled the supplement ecosystem has become—and how much room there is for premium, science-led sub-categories like beauty-from-within.

Regional Insights

North America leads with 39.4% share and US$1.2 Bn in 2024, supported by high beauty awareness and strong consumer spending

In 2024, North America emerged as the dominant region in the beauty supplements market, capturing 39.40% of global share and generating approximately US$1.2 billion in revenue. The region’s leadership was underpinned by high consumer awareness of preventive health and internal beauty solutions, supported by widespread acceptance of supplements that target skin, hair, and nail health across diverse age groups. The United States, in particular, continued to be the largest contributor within the region, benefiting from advanced retail infrastructure, strong e-commerce penetration, and a culture that closely links wellness with aesthetic outcomes, especially through high-profile marketing and influencer engagement. ‘

North American consumers also show strong preference for science-backed, premium formulations with transparent ingredient sourcing, which has boosted demand for products such as collagen peptides and antioxidant blends. Retail availability through pharmacies, health stores, and online platforms made these products highly accessible, increasing repeat purchase frequency throughout 2024. Meanwhile, Canada reported steady growth as consumers embraced beauty supplements alongside broader preventive health trends.

Beauty Supplements Market Regional AnalysisBeauty Supplements Market Regional Analysis

Key Regions and Countries Insights

  • North America
  • Europe
    • Germany
    • France
    • The UK
    • Spain
    • Italy
    • Rest of Europe
  • Asia Pacific
    • China
    • Japan
    • South Korea
    • India
    • Australia
    • Rest of APAC
  • Latin America
    • Brazil
    • Mexico
    • Rest of Latin America
  • Middle East & Africa
    • GCC
    • South Africa
    • Rest of MEA

Key Players Analysis

In 2024, Pfizer Inc. supported beauty and skin health segments through targeted nutraceutical products within its Consumer Healthcare business before divestitures. The company reported total revenue of USD 51.6 billion, with consumer health and nutrition-related sales estimated at ~USD 3.5 billion. Pfizer’s scientific research lent credibility to functional supplement claims.

In 2024, Meiji Holdings Co. expanded its beauty supplement portfolio in Japan and Asia with collagen and nutrient blends. The company recorded consolidated revenue of ¥1,273 billion (JPY), with its Nutrition & Health business contributing around ¥180 billion. Meiji’s strong domestic brand recognition supported product uptake across multiple age groups.

In 2024, Everest NeoCell LLC led in collagen and beauty-oriented supplement formulations, promoting peptides for skin, hair, and nail health. The company reported estimated revenue of USD 95 million, with collagen products constituting ~80% of sales. NeoCell’s focus on science-backed ingredient quality supported retailer placement and brand trust.

Top Key Players Outlook

  • Amway
  • Asahi Group Holdings
  • HUM Nutrition Inc
  • Pfizer Inc
  • Meiji Holdings Co
  • Everest NeoCell LLC
  • Nestlé
  • Nu Skin
  • Meiji Holdings Co., Ltd.
  • Herbalife International of America, Inc.

Recent Industry Developments

In 2024, Asahi Group Holdings, Ltd. engaged indirectly in the beauty supplements and wellness space through its broader food and functional nutrition activities, even though the company’s core business remains beverages and consumer foods. The group reported annual revenue of JPY 2.94 trillion in fiscal 2024, marking growth supported by strategic pricing and premium product focus across regions.

In 2024, Amway continued to shape the beauty supplements segment through its widely recognised Nutrilite brand, which remains central to the company’s nutrition and wellness strategy and influences its beauty-oriented offerings. Amway reported global sales of approximately USD 7.4 billion for the year ending December 31, 2024, with the nutrition category—dominated by vitamins, dietary supplements, and wellness solutions—accounting for 64 % of total sales, signalling strong consumer demand for health-linked and beauty-enhancing products.

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23 12, 2025

Ingredient Research, Market Analysis, and Consumer Education Guide

By |2025-12-23T04:58:38+02:00December 23, 2025|Dietary Supplements News, News|0 Comments


Consequently, market research shows that high dental costs are prompting people to seek preventive oral health strategies. More consumers are using wellness solutions alongside professional care to avoid costly treatments.

Periodontal Disease Prevalence Underscores Prevention Importance

Public health data emphasizes the widespread nature of oral health challenges in the United States. The Centers for Disease Control and Prevention (CDC) reports that 47.2% of American adults aged 30 and older have some form of periodontal disease, affecting approximately 64.7 million adults nationwide. Among adults 65 and older, the prevalence increases to 70.1%.

Periodontal disease typically begins with gingivitis—characterized by gum inflammation and bleeding during brushing or flossing—and can progress to periodontitis, where gum tissue separates from teeth, creating pockets that become infected. Left untreated, periodontitis leads to tooth mobility and tooth loss and has been linked in research to systemic health concerns, including cardiovascular disease, diabetes complications, and respiratory infections.

In light of these widespread rates, people are increasingly seeking ways to prevent problems before they start. Many are trying to take care of their gums early, including trying new oral care products.

Scientific Understanding of Oral Microbiome Influences Consumer Product Interest

Recent scientific advancements have fundamentally shifted prevailing perspectives on oral health maintenance. In addition to traditional efforts to reduce bacterial load, current expert consensus emphasizes the importance of supporting a balanced oral microbiome. A study published in the Journal of Bacteriology in 2010 documented over 700 distinct microorganisms—including bacteria, fungi, and viruses—present in the oral cavity, many of which contribute positively to oral health.

Dr. Floyd Dewhirst, a researcher at the Forsyth Institute and affiliated with Harvard University, explains that the goal is to maintain oral bacterial balance, not eliminate them. When diet, stress, medications, or poor oral hygiene upset this balance, harmful bacteria can increase. This leads to inflammation and tissue damage.

This updated approach to oral health gives consumers more choices, as supplement makers now provide products intended to support beneficial mouth bacteria.

Post-Pandemic Preventive Health Behavior Extends to Oral Wellness

Studies show that people’s habits changed after the COVID-19 pandemic. A 2024 survey by the Council for Responsible Nutrition found that 77% of Americans now take dietary supplements regularly. The main reasons are to support their immune system and control inflammation.

Instead of waiting for dental issues, consider nutrition’s role in protecting teeth and gums—mirroring the mainstream move toward prevention.

This emphasis on proactive oral wellness reflects a wider trend toward early action and the integration of nutrition into regular health routines.

For readers seeking detailed analysis of specific oral health mechanisms, read our comprehensive examination of dental restoration approaches covering tooth decay prevention strategies and gum tissue support research.

Steel Bite Pro Market Positioning: Product Entry in a Growing Category

Company Background and Product Formulation Approach

Steel Bite Pro is positioned as a comprehensive oral health supplement containing botanicals, minerals, and amino acids for individuals seeking preventive dental options. The company recommends consulting the most recent product label for specific ingredient details, as the formula may change over time.

According to the company’s website, Steel Bite Pro is manufactured in an FDA-registered facility and produced in accordance with dietary supplement Good Manufacturing Practice standards (21 CFR Part 111). Facility registration is not FDA product approval. Under the Dietary Supplement Health and Education Act (DSHEA) of 1994, dietary supplements are not approved by the FDA before reaching the market. FDA registration indicates the facility has notified the FDA of its operations and is subject to inspection.

Steel Bite Pro is designed to be used along with, not instead of, regular oral hygiene and dental care.

Ingredient Categories in Oral Health Supplement Formulations

According to the brand’s materials, Steel Bite Pro’s formulation includes ingredients from several categories commonly found in oral health supplements:

Botanical Compounds with Documented Antimicrobial Properties: Scientific research has evaluated plant-based compounds—including berberine, turmeric, grape seed extract, and ginger—for activity against oral pathogens. Most available evidence derives from laboratory and topical studies; data supporting the efficacy of oral supplementation for specific oral health outcomes are limited.

Anti-Inflammatory Botanicals: Inflammation is a fundamental component of periodontal disease pathogenesis. Investigations of turmeric, feverfew, and several root extracts have elucidated anti-inflammatory properties pertinent to oral tissue health, with most research comprising in vitro or topical study designs rather than oral administration.

Nutrients Supporting Connective Tissue: Connective tissue health depends on adequate intake of vitamin C, minerals, and compounds involved in collagen biosynthesis. These components are commonly found in oral health supplement blends designed to support gum health.

Mineral Providers: The primary mineral constituents of tooth enamel are calcium and phosphorus, existing predominantly as hydroxyapatite crystals. Supplement formulations may include botanicals naturally concentrated in minerals essential to dental and periodontal matrices.

Antioxidant Sources: Oxidative stress and inflammation are interconnected in periodontal disease. Research has examined various plant compounds for antioxidant capacity and effects on inflammatory markers.

Amino Acids: Some formulations include amino acids involved in detoxification pathways, antioxidant systems (such as glutathione synthesis), or protein synthesis processes relevant to tissue repair.

View current Steel Bite Pro formulation details

Regulatory Context for Dietary Supplement Manufacturing

Dietary supplement manufacturing in the United States operates under specific regulatory frameworks.

The Current Good Manufacturing Practice (CGMP) regulations for dietary supplements, established under 21 CFR Part 111, require manufacturers to:

  • Establish quality control procedures.

  • Design and construct facilities to prevent contamination

  • Test identity and purity of ingredients.

  • Establish specifications for supplement identity, purity, strength, and composition.

  • Maintain production and process control systems.

  • Maintain complaint handling systems.

  • Maintain records demonstrating CGMP compliance.

These regulations aim to ensure manufacturing quality, consistency, and accurate labeling. However, CGMP compliance does not validate efficacy claims or constitute FDA approval of products.

Ingredient Research Context: Scientific Literature on Botanical Compounds in Oral Health

Critical Framework: The following section examines peer-reviewed research on categories of ingredients commonly found in oral health supplements. This represents ingredient-level research from scientific literature. Individual ingredient research does not guarantee that any specific finished product will produce similar effects. Supplement formulations, dosing, delivery methods, and individual biological variability significantly affect outcomes.

Berberine: Research on Antimicrobial Activity and Oral Bacteria

Scientific Background: Berberine is a bioactive alkaloid compound extracted from several plant species, including Berberis shrubs (barberry), goldenseal (Hydrastis canadensis), and Oregon grape (Mahonia aquifolium). The compound has been used in traditional Chinese and Ayurvedic medicine systems for thousands of years.

Research on Mechanism of Action: Published research in Antimicrobial Agents and Chemotherapy (2008) demonstrates that berberine exhibits broad-spectrum antimicrobial activity. Unlike antibiotics, which typically target specific bacterial strains through single mechanisms, berberine affects multiple bacterial processes, including cell membrane disruption, inhibition of DNA synthesis, and interference with bacterial enzyme systems.

Studies on Oral Health Applications: Research published in the Journal of Indian Society of Periodontology (2012) examined berberine’s effects on periodontal pathogens. The study found that berberine demonstrated antimicrobial activity against Porphyromonas gingivalis, Aggregatibacter actinomycetemcomitans, and Fusobacterium nucleatum—bacterial species strongly associated with periodontal disease in dental research.

A 2015 study in Archives of Oral Biology investigated berberine’s effects on biofilm formation, which is relevant to dental plaque development. Laboratory results showed that berberine reduced biofilm formation by up to 40% and decreased adhesion of Streptococcus mutans, a primary bacterium associated with dental caries, to tooth surfaces under controlled conditions.

Metabolic Research Context: Berberine has been extensively studied for metabolic health applications. A meta-analysis of 27 clinical trials published in Evidence-Based Complementary and Alternative Medicine (2015) found that berberine improved various markers of metabolic syndrome. This research is relevant to oral health because metabolic dysfunction and chronic systemic inflammation are identified in dental research as risk factors for periodontal disease progression.

Research Limitations: Most berberine oral health research involves laboratory studies, topical application, or mouthwash delivery rather than oral supplementation for systemic effects. Oral supplementation evidence for oral health endpoints is limited.

Curcumin (Turmeric): Research on Anti-Inflammatory Effects and Oral Applications

Scientific Background: Turmeric (Curcuma longa) is a flowering plant in the ginger family. Its active compound, curcumin, accounts for approximately 2-8% of most turmeric preparations and is responsible for many of its biological effects studied in research.

Research on Inflammation Pathways: Curcumin functions as an anti-inflammatory compound by inhibiting NF-κB (nuclear factor kappa B), a protein complex that plays a central role in inflammatory response pathways. Chronic activation of NF-κB is implicated in periodontal disease progression, making its inhibition theoretically relevant to inflammatory processes in the gum tissue.

Clinical Research on Oral Health: A 2012 randomized controlled trial published in the Journal of Indian Society of Periodontology compared curcumin mouthwash to chlorhexidine mouthwash—a prescription antimicrobial considered a gold standard in dental practice. The study found that curcumin mouthwash was as effective as chlorhexidine in reducing plaque formation and gingivitis scores over a 21-day period, without the side effects commonly associated with chlorhexidine, including tooth staining, taste alteration, and calculus formation.

Research published in Quintessence International (2016) examined local delivery of curcumin gel as an adjunct to scaling and root planing (professional deep cleaning) in patients with chronic periodontitis. The group receiving curcumin gel showed a significantly greater reduction in pocket depth and clinical attachment gain than the scaling and root planing-only control group at three-month follow-up.

Bioavailability Considerations in Research: The scientific literature notes that curcumin has poor oral bioavailability—very little of the ingested curcumin reaches systemic circulation unchanged. For oral health applications delivered topically (e.g., mouthwashes, gels), this is less relevant, as the compound can exert local effects before being swallowed. For oral supplementation, bioavailability enhancement strategies, such as combining curcumin with piperine (black pepper extract), have been studied, with some research showing increases in bioavailability up to 2000%.

Research Application Context: The research cited primarily involves topical oral application or local delivery rather than oral supplementation. Most available evidence is laboratory-based or involves topical delivery; human evidence for oral supplementation and oral health outcomes remains limited.

Zinc: Research on Roles in Oral Health and Immune Function

Scientific Background: Zinc is a trace mineral naturally present in saliva and essential for numerous biological processes, including immune function, protein synthesis, wound healing, DNA synthesis, and cell division.

Research on Antimicrobial Mechanisms: A 2011 study in Oral Diseases found that zinc ions disrupt bacterial cell membranes and inhibit bacterial enzyme systems. Research indicates that zinc is particularly effective against anaerobic bacteria—the type that thrive in oxygen-depleted environments such as deep periodontal pockets.

Studies on Taste and Smell Function: Zinc is essential for the proper functioning of taste buds and olfactory receptors, according to nutritional research. Zinc deficiency is documented in medical literature as a cause of taste disorders (dysgeusia) and olfactory dysfunction. This is relevant to oral health research because individuals with chronic periodontal disease sometimes report altered taste perception.

Research on Wound Healing: Zinc is required for collagen synthesis, cell division, and immune function—all critical for tissue repair processes. A 2007 meta-analysis in the American Journal of Clinical Nutrition found that zinc supplementation significantly improved wound healing in zinc-deficient patients.

Studies on Salivary Zinc and Periodontal Health: Research published in Biological Trace Element Research (2009) found that salivary zinc levels were significantly lower in individuals with periodontal disease than in periodontally healthy controls, suggesting that zinc status may influence oral health outcomes.

Research Context: Most research on zinc and wound healing focuses on skin wounds or surgical healing rather than oral soft tissue specifically. Zinc supplementation research typically focuses on correcting deficiencies rather than supplementing in individuals who are already zinc-sufficient. Most available evidence is laboratory-based or involves topical delivery; human evidence for oral supplementation and oral health outcomes remains limited.

Beetroot: Research on Nitric Oxide Pathways and Oral Bacteria

Scientific Background: Beetroot (Beta vulgaris) is rich in dietary nitrates, betalain pigments, and various vitamins and minerals, including folate, manganese, and potassium.

Research on Nitric Oxide Conversion: Dietary nitrates from beetroot undergo conversion to nitric oxide (NO) through a two-step bacterial process: nitrate to nitrite to nitric oxide. Research indicates this conversion begins in the mouth via oral bacteria, then continues in the gastric and systemic environments.

Studies on Oral Health Implications: Research published in Nitric Oxide (2014) examined the role of oral bacteria in nitrate metabolism and its effects on oral microbial environments. Researchers found that nitric oxide produced in the oral cavity has antimicrobial properties, particularly against pathogenic bacteria that thrive in low-oxygen environments such as deep periodontal pockets.

A 2016 study in the Journal of Dental Research investigated the effects of beetroot juice consumption in a small human trial. Participants who consumed beetroot juice daily for two weeks showed increased salivary nitrite levels and reduced gingival inflammation scores compared to control groups, though the sample size was limited, and additional research would strengthen these findings.

Research on Tooth Staining Concerns: A common consumer concern addressed in research is whether beetroot causes tooth discoloration. A 2018 study published in the European Journal of Dentistry specifically examined this question. Results showed that beetroot juice did not cause clinically significant tooth staining when compared to baseline or control beverages. The betalain pigments are water-soluble and do not adhere to enamel, unlike tannins from coffee, tea, or red wine.

Research Limitations: Studies on beetroot and oral health are limited in number and sample size. Most available evidence is laboratory-based or involves topical delivery; human evidence for oral supplementation and oral health outcomes remains limited.

Vitamin C and Oral Health: Research on Collagen Synthesis and Gum Tissue

Scientific Background: Vitamin C (ascorbic acid) is a water-soluble vitamin essential for collagen synthesis, the structural protein that gives gums their firmness and resilience. Humans cannot synthesize vitamin C and must obtain it through diet.

Historical Context and Severe Deficiency: Severe vitamin C deficiency (scurvy) famously causes severe gum disease, bleeding, and tooth loss. While outright scurvy is rare in developed countries, subclinical vitamin C insufficiency is more common than often recognized.

Research on Vitamin C Status and Periodontal Disease: A significant study published in the Journal of Periodontology (2000) found that individuals with lower dietary vitamin C intake had higher rates of periodontal disease, even after controlling for other risk factors, including smoking and oral hygiene practices. The research suggests vitamin C status plays a role in gum health independent of mechanical plaque removal.

Research on Collagen Turnover: Collagen in gum tissue is continuously being broken down and rebuilt. Research on collagen metabolism indicates turnover cycles of approximately 8-12 weeks. Adequate vitamin C is necessary for this ongoing regeneration process.

Sources in Supplement Formulations: Many botanical ingredients provide vitamin C: dandelion greens, jujube fruit, certain berries, and citrus-derived compounds. Supplement formulations may include vitamin C from multiple botanical sources rather than isolated ascorbic acid.

Most available evidence is laboratory-based or involves topical delivery; human evidence for oral supplementation and oral health outcomes remains limited.

Antioxidants and Oxidative Stress: Research Context for Oral Health

Scientific Background: Oxidative stress occurs when free radical production exceeds the body’s antioxidant defenses. Research indicates oxidative stress and inflammation are interconnected processes in periodontal disease.

Research on Oxidative Stress in Periodontal Disease: A 2010 study in the Journal of Clinical Periodontology found that individuals with periodontitis had significantly lower levels of salivary and serum antioxidants compared to periodontally healthy controls. The research suggests that oxidative stress may contribute to tissue damage in periodontal disease.

Botanical Sources of Antioxidants: Research has examined various plant compounds for antioxidant capacity:

Grape Seed Extract: Rich in oligomeric proanthocyanidin complexes (OPCs) with demonstrated antioxidant properties in laboratory research

Turmeric: Contains curcumin, which has both anti-inflammatory and antioxidant effects in laboratory and some clinical studies.

Various Berries and Fruits: Provide polyphenols and anthocyanins, which have been studied for antioxidant activity in laboratory research

Research Limitations: Most antioxidant research involves test-tube studies measuring antioxidant capacity under controlled laboratory conditions. Translating this antioxidant capacity to clinical health outcomes in humans is complex and depends on bioavailability, tissue distribution, and other factors. Most available evidence is laboratory-based or involves topical delivery; human evidence for oral supplementation and oral health outcomes remains limited.

Review Steel Bite Pro ingredient research and formulation

Understanding the Oral Microbiome: Educational Context

What Is the Oral Microbiome?

The oral microbiome refers to the complex community of microorganisms that naturally inhabit the mouth, including bacteria, fungi, viruses, and archaea. Research has identified over 700 microbial species in the human oral cavity, making it one of the most diverse microbial ecosystems in the body.

These microorganisms colonize various oral surfaces, including teeth, gums, tongue, cheeks, palate, and throat. The composition varies across oral sites based on factors such as oxygen availability, moisture levels, pH, and nutrient sources.

Role of the Oral Microbiome in Health and Disease

Recent research has shifted understanding from viewing all oral bacteria as harmful to recognizing that many are beneficial and necessary for oral health. A balanced oral microbiome:

  • Competes with pathogenic bacteria for resources and attachment sites, making it harder for disease-causing organisms to establish themselves

  • Produces substances that can inhibit the growth of harmful bacteria

  • Interacts with the immune system in ways that help maintain appropriate inflammatory responses

  • Participates in nitric oxide production from dietary nitrates, which may have antimicrobial and cardiovascular benefits

Dysbiosis: When Balance Is Lost

Oral dysbiosis occurs when the microbial balance shifts, typically with an increase in pathogenic bacteria and a decrease in beneficial species. Factors that can trigger dysbiosis include:

  • Poor oral hygiene allows plaque accumulation.

  • High sugar and processed carbohydrate consumption

  • Smoking and tobacco use

  • Certain medications (antibiotics, medications causing dry mouth)

  • Chronic stress affects immune function.

  • Systemic diseases like diabetes

When dysbiosis occurs, pathogenic bacteria proliferate, produce inflammatory compounds, and create acidic environments that damage gum tissue and tooth enamel.

The Oral-Systemic Health Connection

Research increasingly recognizes that oral health and systemic health are interconnected:

Cardiovascular Disease: Some research suggests associations between periodontal disease and cardiovascular conditions, potentially through inflammatory pathways, though causation versus correlation remains debated

Diabetes: A Bidirectional relationship exists where diabetes increases periodontal disease risk, and severe periodontal disease may affect blood sugar control

Respiratory Infections: Aspiration of oral bacteria can contribute to respiratory infections, particularly in vulnerable populations

Pregnancy Outcomes: Some research associates severe periodontal disease with preterm birth and low birth weight, though mechanisms are not fully understood

Important caveat: These associations do not mean oral health supplements treat or prevent systemic diseases. The research shows correlations and potential mechanisms, but establishing causation requires additional study.

Consumer Education: Understanding Dietary Supplements in Oral Health Context

Dietary Supplements as Complementary Approaches, Not Primary Interventions

Consumer health education emphasizes that dietary supplements represent complementary tools rather than replacements for professional dental care or foundational oral hygiene practices.

According to consumer health research, individuals typically consider oral health supplements for several reasons:

Preventive Support: People maintaining good oral health who want to incorporate nutritional support as part of comprehensive wellness strategies

Nutritional Optimization: Individuals seeking to ensure adequate intake of vitamins, minerals, and compounds relevant to tissue health

Natural Compound Interest: Consumers who prioritize botanical-based approaches and seek alternatives or complements to synthetic compounds

Whole-Body Wellness Perspective: People who understand research linking oral health to systemic health and take integrated approaches to wellness

Bridging Care Gaps: Individuals facing financial or access barriers to frequent professional dental care who seek ways to support oral health between professional visits

Professional Dental Care Remains Primary for Diagnosis and Treatment

Consumer education materials consistently emphasize that certain oral health needs require professional evaluation and intervention that dietary supplements cannot provide:

Diagnosis: Only licensed dentists can diagnose dental disease, assess gum recession severity, identify bone loss through radiographic examination, or interpret clinical findings

Treatment of Active Disease: Cavities, periodontal infections, dental abscesses, and other active disease states require professional intervention through restorative dentistry, scaling and root planing, surgery, or other procedures

Tartar Removal: Calcified tartar deposits (calculus) require mechanical removal through professional cleaning procedures and cannot be eliminated through brushing, flossing, or supplementation

Monitoring and Prevention: Regular professional examinations detect problems early, when treatment is less invasive and typically less expensive

Personalized Guidance: Dentists provide recommendations based on individual risk factors, genetics, medical history, medications, and specific oral health status

What Dietary Supplements Cannot Replace

Consumer protection research emphasizes that certain conditions absolutely require professional dental care:

Dietary supplements cannot replace professional dental procedures, including cleanings, restorative work, periodontal treatments, or surgical interventions. They cannot reverse established damage such as significant gum recession, bone loss, or cavities beyond early demineralization. They cannot substitute for foundational practices, including daily brushing, flossing, and appropriate dietary choices.

Emergency conditions requiring immediate professional care include symptoms such as severe pain, swelling, bleeding, trauma, or signs of infection that require immediate professional dental care. Dietary supplements are not appropriate interventions for dental emergencies.

Evaluating Supplement Quality and Claims

Consumer education resources suggest evaluating supplements based on:

Label Transparency: Complete ingredient disclosure with specific amounts listed

Manufacturing Standards: CGMP certification, third-party testing when available

Realistic Claims: Products avoiding guaranteed outcomes or disease treatment claims

Scientific Foundation: Availability of peer-reviewed research on key ingredients

Company Responsiveness: Clear contact information and responsive customer support

Professional Integration: Products positioned as complements to professional care, not replacements

Regulatory Framework: Dietary Supplement Industry Standards

DSHEA and FDA Oversight of Dietary Supplements

The dietary supplement industry in the United States operates under the Dietary Supplement Health and Education Act (DSHEA) of 1994, which established a regulatory framework distinct from that for pharmaceutical drugs.

Key Regulatory Distinctions:

Pre-Market Approval: Unlike prescription drugs, dietary supplements do not require FDA approval before entering the market. Manufacturers are responsible for ensuring safety and label accuracy before distribution.

Claims Categories: Supplements can make structure/function claims (e.g., “supports gum health”) but cannot make disease treatment claims (e.g., “treats periodontal disease”) without FDA approval as a drug. The FDA explains this distinction in guidance documents available on its website.

Required Disclaimers: Structure/function claims require the disclaimer: “This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.”

Post-Market Surveillance: The FDA monitors supplements after market entry through adverse event reporting systems, product sampling and analysis, facility inspections, and enforcement actions when violations are identified.

Good Manufacturing Practices: Since 2007, dietary supplement manufacturers have been required to follow CGMP regulations under 21 CFR Part 111 to ensure quality, purity, strength, composition, and accurate labeling.

Industry Compliance and Enforcement Landscape

The dietary supplement industry faces ongoing regulatory scrutiny. According to FDA enforcement data, the agency regularly issues warning letters to supplement companies for various violations, including:

  • Making unauthorized disease treatment claims

  • Failing to follow CGMP requirements

  • Product adulteration or contamination

  • Inadequate safety substantiation for new dietary ingredients

  • False or misleading labeling

  • Failure to include required disclaimers

Consumer education materials note that past availability of a product does not guarantee future regulatory compliance, and companies can face enforcement action even after years of operation. The regulatory landscape continues evolving as the FDA and FTC address emerging issues in the supplement industry.

FTC Oversight of Advertising and Marketing Claims

The Federal Trade Commission (FTC) has jurisdiction over dietary supplement advertising and marketing claims. FTC standards require:

Truthfulness: All claims must be truthful and not misleading

Substantiation: Companies must have adequate substantiation for claims before making them

Clear Disclosures: Material information must be disclosed clearly and conspicuously

Endorsement Standards: Testimonials and endorsements must reflect typical consumer experiences or clearly disclose that results are atypical

According to FTC guidance, the Commission evaluates advertising from the perspective of a reasonable consumer and examines whether the overall impression created by advertising is misleading, even if individual statements are technically accurate.

Safety Information and Interaction Potential

General Safety Considerations for Botanical Supplements

While botanical ingredients have long histories of traditional use, natural origin does not automatically indicate safety for all populations or absence of side effects.

Commonly Reported Effects in Research:

Digestive Adjustments: Some botanical compounds and prebiotic fibers can cause temporary digestive changes, including gas, bloating, or altered bowel patterns, as the gut microbiome adapts, typically resolving within 1-2 weeks of consistent use

Allergic Reactions: Individuals with plant allergies should review ingredient lists carefully. Cross-reactivity can occur between botanically related plants. For example, people allergic to ragweed may react to plants in the Asteraceae family, including dandelion, feverfew, or yarrow.

Individual Sensitivity Variation: Response to botanical compounds varies significantly between individuals based on genetics, gut microbiome composition, medication use, and other factors

Drug Interaction Considerations

Multi-ingredient botanical formulations create multiple opportunities for drug interactions. Categories of medications with potential interaction concerns include:

Blood Sugar Medications: Some botanical compounds studied for metabolic effects may influence blood glucose levels. Individuals taking diabetes medications should consult their physician before adding botanical supplements.

Blood Pressure Medications: Certain botanical compounds may affect blood pressure. Individuals taking antihypertensive medications should discuss supplement use with their physician.

Anticoagulants and Antiplatelet Medications: Multiple botanical ingredients have been shown to have mild antiplatelet or anticoagulant effects in research. Individuals taking blood thinners face an increased bleeding risk when combining with botanical supplements.

Immunosuppressant Medications: Some botanical compounds can modulate immune function. Individuals taking immunosuppressant medications should not add botanical supplements without medical supervision.

Medications Metabolized by Cytochrome P450 Enzymes: Many botanical compounds affect drug metabolism pathways. This can alter blood levels of numerous medications.

Special Population Warnings

Pregnancy and Breastfeeding: Many botanical ingredients lack adequate safety data for pregnant or nursing women. Supplementation during pregnancy or while breastfeeding should occur only with an obstetrician’s approval

Scheduled Surgery: Due to potential effects on bleeding, blood sugar, blood pressure, and drug metabolism, individuals should discontinue botanical supplements at least 2 weeks before any surgical procedure, including dental surgery

Liver or Kidney Disease: Individuals with liver or kidney disease should consult their physician before using botanical supplements, as some compounds require hepatic or renal metabolism and excretion

Children and Adolescents: Safety and appropriate dosing of many botanical supplements have not been established for pediatric populations

Multiple Medication Use: Individuals taking three or more prescription medications face a higher interaction risk and should discuss supplement use with their physician and pharmacist

Visit the Steel Bite Pro website for safety information

Product Information and Company Contact

For consumers seeking additional information about Steel Bite Pro specifically, the company provides direct contact options.

Company Contact Information:

According to the company’s website, consumer inquiries can be directed to:

Email: contact@steelbitepro.com

The company website states that customer support responds to questions regarding product formulation, usage guidance, and general product information. For specific medical questions or concerns about interactions with medications or health conditions, the company directs consumers to consult with their healthcare providers.

Product Details:

Additional product details, including current formulation specifics and any satisfaction policy terms, are available on the brand’s website. Readers should confirm the latest information directly with the company, as formulations, terms, and offerings may change over time.

For additional product information, visit the company website

Disclaimer Information

FDA Health Disclaimer

These statements have not been evaluated by the Food and Drug Administration. Steel Bite Pro is not intended to diagnose, treat, cure, or prevent any disease. Steel Bite Pro is a dietary supplement, not a medication or dental treatment. The information presented in this article is for educational and market analysis purposes only and does not constitute medical or dental advice.

Always consult your dentist before starting any new supplement, especially if you have existing dental disease, gum recession, tooth mobility, bleeding gums, tooth pain, loose teeth, gum swelling, or other oral health conditions. Always consult your physician before starting any supplement if you take prescription medications, have chronic health conditions, are pregnant, nursing, or planning surgery.

Professional Dental Care Requirement Disclaimer

This article provides market analysis and ingredient research for educational purposes. It does not constitute dental or medical advice. Steel Bite Pro is a dietary supplement, not a replacement for professional dental care.

If you have bleeding gums, receding gums, tooth pain, loose teeth, gum swelling, dental abscesses, persistent bad breath, tooth sensitivity, or other dental symptoms, consult a licensed dentist immediately. Do not delay or avoid necessary dental treatment based on information in this article or product marketing materials.

Do not change, adjust, or discontinue any dental treatments or medications without your dentist’s guidance and approval. Regular professional dental examinations, cleanings, and periodontal maintenance remain essential for maintaining oral health, detecting problems early, and preventing disease progression. Dietary supplements complement but never replace professional dental care, proper oral hygiene practices (brushing twice daily with fluoride toothpaste, daily flossing, and appropriate mouthwash use when indicated), and healthy dietary habits that limit sugar and acid exposure.

Individual Results Variation Disclaimer

Individual results will vary significantly based on numerous factors, including baseline oral health status, severity of existing dental conditions, consistency of daily supplement use, quality of oral hygiene practices, dietary habits, genetic factors, age, metabolic health, stress levels, sleep quality, prescription medications, smoking status, alcohol consumption, systemic health conditions, and other individual variables.

Dietary supplements require time to show effects—typically weeks to months, not days. Scientific research on nutritional interventions generally indicates timelines of 8-12 weeks before changes may become noticeable, based on tissue turnover cycles and inflammatory modulation processes. While some consumers report subjective improvements, results are not guaranteed and vary widely between individuals.

The ingredient research discussed in this article represents findings from studies on isolated compounds, often at specific doses or via administration routes (topical gels, mouthwashes, local delivery) that differ from oral supplementation approaches. Ingredient-level research demonstrating efficacy does not guarantee that a supplement containing those ingredients will produce the same effects in users. Individual ingredient efficacy does not equal finished product efficacy.

Affiliate Relationship Disclosure

This article contains affiliate links. If you purchase through these links, a commission may be earned at no additional cost to you. This compensation does not influence the accuracy, neutrality, or integrity of the information presented.

All ingredient analysis is based on peer-reviewed research from scientific databases, including PubMed, Google Scholar, and university research repositories, as well as publicly available information from reputable health organizations and government agencies. Product claims attributed to the manufacturer represent the company’s marketing statements as published on the company’s official website and materials and have not been independently verified by this publisher.

The author receives compensation for referrals made through affiliate links but maintains editorial independence in presenting scientific research, safety information, limitations of available evidence, realistic expectations, and critical analysis. This article presents both research supporting the use of ingredients in oral health contexts and the limitations of available evidence, gaps in research, and areas where additional study would be valuable.

Pricing and Terms Disclaimer

Product details, formulation specifics, satisfaction policies, and company terms are subject to change without notice. Consumers should verify all current information directly with the manufacturer before making purchasing decisions.

The manufacturer may modify product formulations, satisfaction guarantee terms, or other policies at any time without advance notification. Always confirm current details on the official company website before making decisions.

The publisher is not responsible for discrepancies between information available at the time of article publication and current terms published by the manufacturer. Current terms as published on the manufacturer’s website supersede any information in this article if differences exist.

Publisher Responsibility Disclaimer

The publisher of this article has made every effort to ensure accuracy at the time of publication based on available peer-reviewed research, manufacturer disclosures, industry standards, and regulatory guidelines. We do not accept responsibility for errors, omissions, or outcomes resulting from the use of the information provided.

Readers are encouraged to verify all details directly with the manufacturer, conduct independent research on ingredients and their safety profiles, consult peer-reviewed medical and dental literature, and, most importantly, consult their dental care provider and physician before making health decisions based on information in this article.

This article does not create a doctor-patient relationship, dentist-patient relationship, or professional advisory relationship between the publisher and readers. The article represents market analysis, research compilation, and consumer education, not personalized health advice.

Ingredient Safety and Drug Interaction Warning

Some ingredients commonly found in oral health supplements may interact with certain medications or exacerbate certain health conditions. Examples include:

Certain botanical compounds may affect blood sugar levels and interact with diabetes medications. Other botanical ingredients may affect blood clotting and interact with anticoagulant medications. Some compounds may affect blood pressure and interact with antihypertensive medications. Various botanical ingredients may be metabolized by or affect cytochrome P450 enzymes, potentially altering the blood levels of numerous prescription medications.

Individuals taking prescription medications—particularly for diabetes, high blood pressure, blood clotting disorders, immune system conditions, or any chronic condition—must consult their healthcare provider before starting any botanical supplement. Pregnant or nursing women should consult their physician before use. Individuals with liver disease, kidney disease, gallbladder disease, bleeding disorders, autoimmune conditions, scheduled for surgery, or taking multiple prescription medications should seek medical advice before supplementation.

This warning information is general in nature and not exhaustive. Always disclose all supplement use to all healthcare providers, including dentists, physicians, surgeons, and pharmacists. Bring supplement bottles to medical appointments so your healthcare provider can review the specific ingredients and potential interactions with your medications and health conditions.

Not a Substitute for Medical Care Disclaimer

This article is not a replacement for prescribed medical treatment for any oral health condition, systemic disease, or health issue. Dietary supplements are not treatments for gum disease, gingivitis, periodontal disease, periodontitis, tooth decay, dental caries, dental infections, oral cancer, or any medical condition. They are intended to support general wellness as part of comprehensive health approaches.

If you are currently taking medications, have existing health conditions, including dental disease, or are considering any major changes to your health regimen, consult your physician and dentist before starting any new supplement. Do not change, adjust, or discontinue any medications or prescribed treatments without your physician’s explicit guidance and approval.

Dental and medical emergencies require immediate professional care, not dietary supplementation. Seek emergency care for severe symptoms or any condition that appears to be worsening rapidly.

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  17. Bagchi D, Garg A, Krohn RL, et al. “Oxygen free radical scavenging abilities of vitamins C and E, and a grape seed proanthocyanidin extract in vitro.” Research Communications in Molecular Pathology and Pharmacology. 1997;95(2):179-189.

  18. Pizzorno JE, Murray MT. Textbook of Natural Medicine. 4th ed. Churchill Livingstone; 2012.

  19. Sato Y, Suzaki N, Nishikawa M, et al. “Phytochemical flavones isolated from Scutellaria baicalensis and their antibacterial activity against methicillin-resistant Staphylococcus aureus.” Journal of Ethnopharmacology. 2000;72(3):483-488.

  20. Federal Trade Commission. “Dietary Supplements: An Advertising Guide for Industry.” Published 2023.

Article Publication Information:

Word Count: 9,412 words Publication Date: December 2025 Market Focus: Oral health supplement category growth trends and consumer education Compliance Standards: Globe Newswire editorial guidelines, FDA DSHEA requirements, FTC advertising standards Research Foundation: Peer-reviewed scientific literature and market analysis data

For Consumer Inquiries: Contact: contact@steelbitepro.com

For additional product information, visit the company website

This article presents market analysis and a compilation of educational research. It does not constitute medical, dental, or health advice. Consumers should consult qualified healthcare professionals before making health decisions. All product-specific claims are attributed to the manufacturer and have not been independently verified by this publisher. Dietary supplements are not intended to diagnose, treat, cure, or prevent any disease.

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23 12, 2025

green tea benefits: Nutrition experts recommend this tea in winter for immune support

By |2025-12-23T02:57:39+02:00December 23, 2025|Dietary Supplements News, News|0 Comments


As winter nears, several people search for natural ways to remain healthy and resilient. Tea has long been praised for comfort, warmth, and wellness advantages, and nutrition experts remain to highlight certain varieties that may aid immune health. From antioxidant-rich green tea to soothing herbal blends, selecting the right tea and drinking it regularly can be a simple addition to a balanced winter habit.“The best teas for immune support this winter are green teas, especially matcha,” states Anney Norton, a tea blend expert and founder of Dream Tea NYC. “I recommend pairing a daily cup of high-quality green tea with ginger-oriented teas that provide anti-inflammatory support.”

Consistency Matters More Than Quick Fixes

Rather than using tea only when you are feeling unwell, Norton highlights the importance of long-term routines. “For optimal immune support, consistency matters more than intensity,” she states. “A daily cup of quality green tea or matcha throughout winter will serve you better than only reaching for immune-support teas when you feel a cold coming on.”

According to Norton, the immune system reacts the best to steady, gentle reinforcement instead of sporadic interventions. Supporting immunity is less about responding to symptoms and more about maintaining immune resilience.

How Green Tea Strengthens Immune Defenses

Green tea has achieved its reputation as a winter wellness staple due to its scientifically supported influence on immune function.

“Green teas are particularly powerful because they’re loaded with EGCG (epigallocatechin gallate), a catechin that directly enhances immune function through multiple pathways,” Norton cites. “EGCG increases the production and activity of regulatory T cells—specialized immune cells that help your body distinguish between genuine threats and false alarms, preventing both under- and over-reaction.”

This regulation is particularly significant during cold and flu season, when the immune system can become strained or depleted.

The Role of L-Theanine in Immune Response

Green tea also has L-theanine, an amino acid connected to immune signaling. Norton emphasizes research showing its advantages, referencing a study in Proceedings of the National Academy of Sciences.

“The tea drinkers showed significantly higher interferon-gamma production, indicating significantly enhanced immune response,” she states.

Interferon-gamma is a protein that supports the body to react more effectively when exposed to infections, making L-theanine a significant component of green tea’s immune profile.

Why Matcha Offers an Even Stronger Boost

For those looking for a more concentrated choice, matcha provides amplified advantages. “Matcha takes these benefits further because you’re consuming the entire ground tea leaf rather than just steeping water-soluble compounds,” Norton cites. “This means you’re getting the full spectrum of nutrients, including fat-soluble antioxidants that never make it into steeped tea.”

Research indicates that matcha may have up to 137 times more EGCG than traditional green tea. “This translates to more potent T-cell enhancement and stronger antiviral activity from every cup,” Norton states, adding that ceremonial-grade matcha also offers higher levels of L-theanine “due to the shade-growing process used for premium leaves.”

Caffeine Considerations

Despite its advantages, matcha’s higher caffeine content, approximately 70 milligrams per serving compared to 30–50 milligrams in green tea may not fit everyone, mainly later in the day. Norton recommends balancing energy with rest by incorporating matcha in the morning with calming teas overnight.

She advises ending the day with chamomile. “You get energized, immune-boosted days and the deep, restorative sleep that allows your immune system to do its repair work at night,” Norton cites.

Ginger Tea: A Powerful Complement

While green tea functions directly on immune cells, ginger tea aids immunity in a different way. “While green tea and matcha enhance immune cell function directly, ginger tea works through complementary anti-inflammatory pathways,” Norton mentions.

“Ginger’s active compounds gingerols and shogaols inhibit inflammatory enzymes (COX-2) and suppress pro-inflammatory cytokines.”

Reducing inflammation is important because chronic inflammation can weaken immune efficiency. “Ginger keeps your immune system balanced and responsive rather than overreactive or exhausted,” Norton describes. “It also helps some of the classic early cold symptoms, like sore throat, and can even help with some of the joint pain and tenderness that can happen with the flu.”

For convenience, Norton advises combining advantages in one cup by opting customizable blends. Popular combinations are green tea with ginger, lemon, and osmanthus, or green tea infused with peach and ginger.

Why Chamomile Still Matters

Chamomile may not directly activate immune cells, but it has a significant supporting role. “While chamomile doesn’t directly boost immune function, it significantly improves sleep quality, and poor sleep is one of the most potent immune suppressors,” Norton states. “Think of chamomile as protecting your immune system by addressing one of its biggest vulnerabilities.”

Disclaimer:This content is intended for informational and educational purposes only and does not constitute medical advice. Always consult a qualified healthcare expert with questions in regard to your health.

FAQs:

1. Why is green tea often advised for immunity?
Green tea has antioxidants that help support immune cell function. These compounds may help the body respond more efficiently to seasonal challenges.

2. Is matcha better than regular green tea?
Matcha offers a more concentrated source of nutrients because the whole leaf is consumed. However, it also has more caffeine, which may not suit everyone.

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23 12, 2025

This Weight-Loss Fave Fiber Supplement Can Help With Brain Health

By |2025-12-23T00:56:34+02:00December 23, 2025|Dietary Supplements News, News|0 Comments


Fiber has a great reputation for helping people keep their bowel movements regular, and during the Ozempic boom, it’s become an even more buzzy nutrient thanks to its ability to support weight loss and improve satiety (like GLP-1s). But this special carbohydrate can actually do so much more than just keep you on a schedule and promote good gut health. New research suggests fiber could actually support good brain health, too.

Right now, only about 5 percent of Americans get enough fiber in their diet, so it might be time to rethink how much fiber you’re getting on a daily basis. One way is by loading up on psyllium husk, which has been dubbed “nature’s Ozempic.”

Here’s why you may want to consider adding more fiber—and psyllium husk—to your day, plus how to actually go about it, according to experts.

Meet the experts: Molly Rapozo, RDN, is a senior nutrition and health educator at Pacific Neuroscience Institute at Providence Saint John’s Health Center in Santa Monica, CA; Jessica Cording, RD, CDN, is the author of The Little Book of Game-Changers; Clifford Segil, DO, a neurologist at Providence Saint John’s Health Center in Santa Monica, CA.

How does fiber boost brain health?

Recent research shows loading up on fiber can do your brain health a solid.

One randomized controlled trial published in Nature Communications last year split 36 pairs of twins into two groups: One took a placebo and the other took a daily fiber supplement for 12 weeks. The researchers discovered that people in the fiber supplement group did better on brain function assessment tests and showed better reaction times and processing speeds than those in the placebo group.

A slightly older rat study also found that psyllium husk in particular reduced white matter damage in the brain, which is a symptom associated with dementia.

The link between getting plenty of fiber and good brain health is likely tied to the gut-brain axis, a network of connections between your gut and your brain, says Clifford Segil, DO, a neurologist at Providence Saint John’s Health Center in Santa Monica, CA.

“I often see patients with gastrointestinal complaints like abdominal pain also have neurological complaints like headaches,” he says. “Fiber is important for gastrointestinal health as it helps our bodies excrete out waste and aids in flushing our system.”

Dr. Segil says he’s seen patients have fewer headaches when they’re able to take care of their gut health. “A happy gut with fiber may cause a happy brain by helping our bodies clean themselves out and balance things better,” he says.

Is psyllium husk a good source of fiber?

Let’s back up a sec: Psyllium husk is a soluble plant fiber, which means it pulls in water and creates a gel-like substance in your gut, says Jessica Cording, RD, CDN, author of The Little Book of Game-Changers. “It helps with building stool bulk and can help you to feel full,” she explains.

And yes, Cording says that psyllium husk is a great tool for upping your fiber intake. “It can support heart health, digestive regularity, and weight management,” she says.

A diet high in fiber—including psyllium husk—”is healthy for diabetes, hypertension, and for both cardiovascular and cerebrovascular health,” Dr. Segil says.

What other sources of fiber can I add to my diet?

Eating a diet rich in plants is the best way to meet your fiber needs, according to Molly Rapozo, RDN, senior nutrition and health educator at Pacific Neuroscience Institute at Providence Saint John’s Health Center in Santa Monica, CA. And those same fiber sources tend to be nutrient rich, so it’s a win-win.

Here are some of the best sources of fiber, according to the Dietary Guidelines for Americans:

  • Bran cereal
  • Lima beans
  • Artichokes
  • Lentils
  • Guava
  • Broccoli
  • Raspberries
  • Popcorn
  • Cooked bulgar
  • Pumpkin seeds

How much fiber should I be consuming?

Fiber recommendations vary slightly by age and gender, but it’s generally suggested that you aim to consume 28 grams a day.

If you’re taking fiber supplements for the first time, start small (think ½ teaspoon in an 8-ounce glass of water once a day) before ramping up, according to Mount Sinai. You can gradually up your dosage as time goes on.

What are some other good fiber supplements?

While psyllium husk is a common fiber supplement, Cording says you can also get in fiber by adding chia seeds to your diet. “You can also look for products that use chicory root and inulin as the fiber source,” she says.

Again, if you’re able to get fiber in your diet from your diet alone, that’s great. But if you need a boost, adding psyllium husk to your day isn’t a bad idea—for your body or your mind.

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“This can work to relieve both constipation by increasing stool bulk and diarrhea by helping to absorb water and slow down stool passage in the colon,” dietitian May Zhu, RD, the founder of Nutrition Happens, previously told WH. It’s also versatile and can be added to beverages or soft foods.

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This capsule is designed to help you maintain healthy blood sugar levels, lower cholesterol, promote digestion and gut health, and support regular bowel movements. Another perk? Metamucil is a top-recommended brand, according to our experts, so you can trust the quality and purity of your supps.

GOGO Fiber Gummies

O Positiv GOGO Fiber Gummies

“These are orange sorbet-flavored and get their fiber from chicory root providing three grams of fiber per two gummies,” Amy Gorin, RDN, an inclusive plant-based dietitian previously told WH. Taking them will keep you regular and support good gut bacteria.

FiberMend Prebiotic Powder

Thorne FiberMend Prebiotic Powder
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This plant-based, water-soluble fiber helps you deal with constipation and aids digestion overall. It’s sugar-free, mixes easily with your favorite bev, and it’s rich in antioxidants.

Headshot of Korin Miller

Korin Miller is a freelance writer specializing in general wellness, sexual health and relationships, and lifestyle trends, with work appearing in Men’s Health, Women’s Health, Self, Glamour, and more. She has a master’s degree from American University, lives by the beach, and hopes to own a teacup pig and taco truck one day.



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22 12, 2025

key facts, research studies, and advice for journalists

By |2025-12-22T22:55:43+02:00December 22, 2025|Dietary Supplements News, News|0 Comments


by Naseem S. Miller, The Journalist’s Resource
December 22, 2025

Whether it’s on TV commercials or posts by social media influencers, dietary supplements are marketed as a daily need to maintain optimal health, or as a quick fix for a range of ailments and conditions, from hair loss to weight management.

And although dietary supplements like vitamins can benefit some people, including older adults, pregnant people and individuals at risk of nutrient deficiencies, there’s little evidence that they benefit the average healthy person. Some supplements may contain contaminants that are harmful, and some may interact with prescription or over-the-counter medications.

However, these products continue to grow in popularity, including a surge during the COVID-19 pandemic.

A 2023 study published in Nutrients finds that the COVID-19 pandemic led to a significant surge in the use of dietary supplements globally, mainly for their perceived immune-boosting effects, even though there’s very little known about how effective these products are against COVID-19.

One reason for the persisting popularity of supplements in the U.S. is that it’s “just ingrained into the American society that we should be able to go and treat ourselves when we have health issues, and not have to necessarily get the advice or prescriptions from doctors,” says Dr. Pieter Cohen, an associate professor at Harvard Medical School and a national expert on dietary supplements.

Because the Food and Drug Administration does not approve dietary supplements before they’re marketed, there is no complete list of supplements sold in the U.S. There are between 80,000 to 100,000 different supplements available to consumers in the U.S., according to an estimate by the agency.

The future of supplement regulation under the current administration is still unclear. The FDA could introduce new regulatory hurdles that may not be welcomed by the industry, according to an article in Axios, published in October. Meanwhile, news reports in December suggest that the FDA may relax a warning label rule for supplements, according to NBC News.

If you’re reporting on the topic, it’s important to inform your audiences about the promises, limitations and potential harms of over-the-counter supplements.

Below, we’ve gathered credible sources of information, fact-checked data and peer-reviewed research studies to help you with your reporting. We address the following topics:

The questions are followed by two pieces of advice for journalists, five research studies about dietary supplements and more reporting resources.

What are dietary supplements?

The term “dietary supplement” was defined in the Dietary Supplement Health and Education Act of 1994 as “a product intended for ingestion that, among other requirements, contains a ‘dietary ingredient’ intended to supplement the diet.”

The term “dietary ingredient” includes:

  • Vitamins and minerals, such as multivitamins, individual vitamins, calcium, and iron.
  • Herbs and other botanicals, such as echinacea and ginger.
  • Amino acids, such as tryptophan and glutamine.
  • “Dietary substances” that are part of the food supply, such as enzymes and live microbials (commonly referred to as “probiotics”).
  • Concentrates, metabolite extracts, or combinations of any dietary ingredient from the categories listed above.

Dietary supplements may have two types of ingredients:

  • Dietary ingredients, listed above.
  • Other ingredients, such as fillers, binders, preservatives, sweeteners and flavorings.

Dietary supplements may be found in many forms, such as pills, tablets, capsules, gummies, softgels, liquids, powders, teas and bars. Topicals or inhaled products are not supplements.

What are some key supplement use statistics in the U.S.?

The use of dietary supplements has been on the rise in the U.S., increasing from 50% of adults and children in 2007 to 56% in 2018, according to a 2022 survey study published in the Journal of Nutrition.

A 2024 study analyzing data from the 2011 to 2018 National Health and Nutrition Examination Survey, including a total of 12,529 participants, found that more than 70% of the respondents took dietary supplements daily. Nearly 40% said they had been taking supplements for more than five years, and 67% said they were “highly adherent to at least one supplement.”

The U.S. dietary supplements market size was estimated at $64 billion in 2024 and is projected to reach $124 billion by 2033, according to a market analysis report by Grand View Research.

The global value of the dietary supplements market was estimated to be around $152 billion in 2021, and expected to grow to $300 billion by 2028, according to a 2023 study, “A Global Overview of Dietary Supplements: Regulation, Market Trends, Usage during the COVID-19 Pandemic, and Health Effects,” published in Nutrients.

How are supplements regulated and how are the regulations enforced?

The Dietary Supplement Health and Education Act of 1994 is the main legal framework that governs supplements today, shaping debates over consumer safety, misleading health claims and whether supplements should face stricter oversight similar to drugs. DSHEA classifies supplements as a category of food rather than drugs.

The act created a distinction based on whether an ingredient was on the market prior to its passage.

  • Dietary ingredients marketed in the U.S. before the passage of the act are presumed safe and do not require FDA safety review.
  • Ingredients introduced after the act’s passage are classified as New Dietary Ingredients. This means manufacturers must submit a notification to the FDA 75 days prior to marketing, providing information on why the ingredient is “reasonably expected to be safe.”

Unlike prescription drugs, dietary supplements are not evaluated by the FDA for safety or efficacy before arriving on the market. Manufacturers are not required to perform clinical trials. “In fact, in many cases, firms can lawfully introduce dietary supplements to the market without even notifying FDA,” according to the agency.

DSHEA created a post-market or reactive regulatory approach for the FDA, placing the burden of proof on the government to show that a product is unsafe, adulterated or misbranded before it can be removed from the market.

The legislation requires supplement manufacturers to notify the agency when they introduce a new dietary ingredient into the market. But in 2022, the FDA estimated that it had not been informed about at least 3,400 new ingredients in available supplements, according to a STAT+ article.

The FDA has several enforcement tools to remove hazardous ingredients from dietary supplements. They include issuing warning letters to manufacturers, requesting or mandating that manufacturers recall products, and publishing public notices, according to a 2022 study published in JAMA.

Still, as Cohen has found in his research, some products remain on the market for years after the FDA issues warning letters about them.

The FDA and the Federal Trade Commission share responsibility for the oversight of dietary supplements and related promotion. The FDA generally is responsible for safety, quality and labeling, and the FTC is responsible for regulating advertising. Both agencies have the authority to take enforcement actions against dietary supplements and firms in case of violations.

Globally, dietary supplements are also loosely regulated and there is little agreement between countries on the definitions or terminology used to classify the supplements and regulatory requirements, according to a 2023 study published in Nutrients.

What are the benefits and harms of taking supplements?

Certain vitamins can prevent diseases that are the result of vitamin deficiencies. For instance, vitamin C can prevent scurvy and vitamin D can prevent rickets. Patients who have undergone bariatric surgery may need supplements. Lack of folic acid in pregnant people has been associated with an increased risk of certain neurological defects in babies, according to a 2021 reporting resource by SciLine, which summarizes research findings about the benefits of long-term use of supplements and vitamins.

“On the other hand, there might be extracts of particular botanicals that have no proven benefit, that are sold right next to the vitamins,” Cohen says.

Supplements can also interfere with prescription medications. For example, herbal St. John’s wort, often used for mood disorders, may interfere with the effectiveness of certain medications such as antidepressants, blood thinners, birth control pills and some cancer treatments, according to a January 2025 article in the National Institutes of Health’s MedlinePlus Magazine.

The most serious safety issue of dietary supplements is the sale or marketing of products that are adulterated with illegal or unsafe ingredients whose efficacy hasn’t been shown.

In a 2021 study, Cohen and his co-authors found several unapproved drugs, including ones that were not approved for human use in the U.S., in over-the-counter supplements marketed to improve memory and cognitive function.

In another analysis, published in JAMA Network in 2023, Cohen and his co-authors found that the labels of 89% of performance-enhancing dietary supplements did not accurately declare the ingredients that were in the products, and 12% of products contained ingredients prohibited by the FDA.

The three most problematic dietary supplement categories in the U.S are sexual enhancement supplements, weight loss supplements, and sports performance and bodybuilding supplements, according to the 2023 study.

Are dietary supplement serving sizes standardized?

No. According to the FDA, “Other than the manufacturer’s responsibility to meet the safety standards and labeling requirements for dietary supplements and to comply with current good manufacturing regulations, there are no laws or regulations that limit the serving size of a dietary supplement or the amount of a dietary ingredient that can be in a serving of a dietary supplement. This decision is made by the manufacturer and does not require FDA approval.”

What do stamps on supplement labels really tell you?

There are a variety of quality and safety stamps on the labels of dietary supplements, and not all carry the same weight.

“Most of [the stamps] are not going to be very useful,” Cohen says.

In some cases, the supplement manufacturer has paid a company to give it a stamp of approval on its label, Cohen says.

“My recommendation is to go for the third-party programs that are very solid,” he said.

Here are two organizations that Cohen trusts:

  • U.S. Pharmacopeia is an independent, scientific nonprofit organization focused on building trust in the supply of safe and quality medicines.
  • NSF is an independent organization that plays a pivotal role in the development of robust public health standards.

Advice for journalists

Cohen offered the following advice to journalists when reporting on dietary supplements.

Report on the nuances of supplements.

Certain supplements are effective at a certain dose, similar to medications.

“Let’s take creatine, for example,” which can be used to slightly increase the ability to lift weight, Cohen says.

The supplement is sometimes portrayed in news stories and other content as either great or dangerous to health, but the reality is more nuanced.

“When it comes to things that have some evidence that they work, what’s often missed is the idea that the only way something’s going to work is if you’re taking an accurately labeled product at the proper dose that has been shown in studies to be effective,” Cohen says.

“Just like a prescription medication, you wouldn’t be like, ‘Oh, let’s take Lipitor at any dose’. We know that makes no sense,” Cohen says. “It’s the same thing for all the supplements. We just need to realize they’re just like medications and take them seriously, and that part of the story is often lost.”

Remind your audience that an FDA warning letter doesn’t mean the supplement will be removed from the market right away.

The FDA’s primary responsibility is to ensure the safety and purity of dietary supplements after they are marketed and to remove any product that may be potentially dangerous to consumers from the market, according to a 2023 study published in the journal Nutrients.

But researchers like Cohen, who study supplements, say that some products remain on the market for years after the FDA issued warning letters about them.

“The FDA has not been doing its job to even use the laws it does have to ensure the safety of supplements,” for the last several decades, Cohen says. “So people need to understand that the FDA has not, historically and will continue not to be, responsible in terms of doing its little part in trying to ensure a little bit of supplement safety.”

In a 2022 study, listed below, Cohen and his co-authors find that nine of the 31 products they analyzed remained available for purchase online for an average of 6 years after the FDA issued warning letters.

Five research studies to consider

Recalls, Availability, and Content of Dietary Supplements Following FDA Warning Letters
Pieter A Cohen, Bharathi Avula, Kumar Katragunta, and Ikhlas Khan. JAMA, July 2022.

  • This study investigates whether dietary supplements that received FDA warning letters for containing prohibited stimulants, such as amphetamine-like substances, were recalled, removed from the market, or became free of banned ingredients.
  • Researchers identified 31 supplements that had received FDA warning letters for the presence of three prohibited stimulants: amphetamine analogue β-methylphenethylamine (BMPEA), the ephedrine analogue methylsynephrine (Oxilofrine), or dimethylamylamine analogue octodrine (DMHA or octodrine). The FDA issued warning letters for these stimulants in 2015, 2016, and 2019, respectively, mandating that manufacturers inform the FDA of the steps the firm will take to correct the violation and prevent similar violations in the future.
  • Of these 31 products, one was recalled by the manufacturer. Nine of the 31 products — 29% — remained available for purchase online for an average of 6 years after the FDA issued warning letters.
  • The results may not be generalizable to all dietary supplements subject to FDA warning letters. It’s also not clear whether the presence of adulterants might vary from batch to batch or over time.

Vitamin, Mineral, and Multivitamin Supplementation to Prevent Cardiovascular Disease and Cancer: Preventive Medication
Elizabeth O’Connor, et al. U.S. Preventive Services Task Force, June 2022.

  • Across 84 studies with a total of 739,803 participants, the researchers found that common supplements, including vitamin D, vitamin E, calcium, vitamin C, B vitamins, magnesium, selenium and zinc, generally do not reduce the risk of cardiovascular disease, cancer or death.
  • Use of multivitamins was associated with a very small reduction in the overall risk of cancer and a small decrease in lung cancer.
  • Consuming beta carotene supplements increases the risk of lung cancer, especially among smokers or in people exposed to asbestos. It also increased the risk of cardiovascular death.
  • Use of other vitamins also carries risk. For instance, the use of vitamin E was associated with an increased risk of hemorrhagic stroke. Use of 1,000 units or more of vitamin D was associated with an increased risk of kidney stones.

Dietary Supplements — For Whom? The Current State of Knowledge about the Health Effects of Selected Supplement Use
Regina Ewa Wierzejska. International Journal of Environmental Research and Public Health, August 2021.

  • The goal of this scoping review is to present what is known about the effects of using selected dietary supplements for chronic diseases and the risks associated with their use.
  • The author’s review of literature shows that vitamin and mineral supplements neither lower the risk of cardiovascular diseases nor prevent the development of cancers in healthy people.
  • Most of the randomized controlled trials analyzed in this review found that vitamin and mineral supplements do not lower the risk of cardiovascular diseases and cancer.
  • For weight loss supplements, the use either has a marginal benefit or is completely ineffective. Meanwhile, their side effects and the risk of contamination with illegal substances remain concerning.

Label Statements and Perceived Health Benefits of Dietary Supplements
Joanna Nicole Assadourian, Eric D. Peterson, and Ann Marie Navar. JAMA Network Open, September 2025.

  • Researchers conducted two online surveys of U.S. adults, one for a fish oil supplement (2,239 participants) and one for a fictional supplement called Viadin H (2,164 participants).
  • For each survey, participants were randomized to one of four labels that were otherwise identical but had different health-related statements on the label. The surveys were conducted between January and March 2024.
  • Participants exposed to claims that included heart-related words, or brain health or cognitive function wording on labels, were more likely to believe the supplement did what they claimed, even for the fictional supplement.
  • The results show that consumers often interpret vague label statements as implying disease prevention or treatment benefits, even though such wording is not intended to imply specific effects on disease prevention under FDA rules.

A Global Overview of Dietary Supplements: Regulation, Market Trends, Usage during the COVID-19 Pandemic, and Health Effects
Ouarda Djaoudene, et al. Nutrients, July 2023.

  • This overview provides a global comparison of supplement regulation and cross-border sales.
  • The authors provide market numbers, growth trends and usage statistics.
  • In addition, the study examines how the COVID-19 pandemic affected supplement use globally.

Additional resources

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22 12, 2025

5 Supplements To Avoid if You Have High Blood Pressure

By |2025-12-22T20:54:40+02:00December 22, 2025|Dietary Supplements News, News|0 Comments


Managing hypertension (high blood pressure) is necessary to lower your risk of other health conditions, like heart attack or stroke. To best manage high blood pressure, you may need to avoid certain supplements because they can affect your blood pressure or make your blood pressure medication less effective.

Vitamin D is a vitamin naturally found in certain foods and available as a supplement. Your body also makes vitamin D when your skin is exposed to ultraviolet (UV) rays from the sun. Vitamin D is necessary for many body functions, like bone health and inflammation.

Some researchers have found that vitamin D may help treat high blood pressure, specifically doses of 200-8,000 International Units (IU) per day. Doses of vitamin D larger than 10,000 IU per day can lead to dangerous side effects, like high levels of calcium (hypercalcemia). Hypercalcemia can cause many issues over time, including high blood pressure.

High doses of vitamin D can also interact with certain diuretics (water pills) used to treat high blood pressure. This interaction can cause your body to not get rid of enough calcium, raising your calcium levels and possibly raising your blood pressure.

Talk to your primary care provider about your vitamin D levels. They can test your levels to determine if vitamin D supplementation would be useful for you and your blood pressure.

Licorice root (Glycyrrhiza glabra) is an herb used as a flavoring in food, candy, and tobacco products. In traditional medicine, the root has been used to treat lung disease, liver disease, and wounds.

Licorice contains glycyrrhizic acid (GA), an ingredient that can raise blood pressure and cause serious side effects if you have high blood pressure. GA doses as low as 100 milligrams daily have been shown to raise blood pressure.

Supplements with GA can also interact with diuretics and blood pressure medications. The supplement may affect how well blood pressure medication works and raise your risk of side effects. Specifically, licorice root can raise sodium levels and lower potassium levels in your body. This effect, combined with a diuretic, can lead to dangerously low levels of potassium.

If you have high blood pressure, it’s best to avoid using products with licorice root.

St. John’s wort (Hypericum perforatum) is a plant used to treat symptoms of depression and menopause. Despite its historical use as a traditional medicine, the plant may dangerously interact with a variety of medications. St. John’s wort weakens the effects of many medications, including some used to treat high blood pressure.

Examples of blood pressure medications that interact with St. John’s wort include:

  • Procardia (nifedipine)
  • Talinolol
  • Verelan (verapamil)

These interactions likely occur because St. John’s wort blocks the medication from being absorbed in the body as it normally would.

Talk with your healthcare provider before taking St. John’s wort. They can tell you if the supplement may interact with any other medications or supplements you are taking.

Arnica is a flower in the sunflower family. The flower has been used to help with bruising, inflammation, and swelling when applied directly to the skin.

Experts recommend against taking arnica by mouth due to a risk for significant side effects. These side effects may include high blood pressure, increased bleeding, vomiting, diarrhea, and damage to your heart or other organs.

Bitter orange (Citrus aurantium) is taken from the fruit or peel of a bitter orange. The fruit and its peel can be used to add flavor to drinks or aromas to perfumes. The bitter orange supplement is often used to help with weight loss and improve sports performance.

Bitter orange contains p-Synephrine, a type of stimulant similar to ephedrine. The U.S. Food and Drug Administration (FDA) has banned ephedrine stimulants because they can cause health issues like stroke and heart attack. Though bitter orange is not banned, it should be used with extreme caution.

Studies have shown that bitter orange supplements can raise blood pressure and heart rate. The supplement can also raise your risk for other serious side effects like stroke and heart attack. However, bitter orange found in food and drinks is not likely to affect your blood pressure or cause these side effects.

Talk with your healthcare provider before taking bitter orange.

People may respond to certain supplements differently. Factors that may affect how you respond to a supplement include genetics, diet and nutrition, age, gut health, and overall health status. Take note of any side effects or symptoms you experience when starting a new supplement or vitamin.

Before starting any new vitamins or supplements, talk to your doctor. They can help you decide if the vitamin or supplement would be useful and safe for you to take. Your doctor can also compare the new supplement to all the medications, vitamins, and other supplements you already take to identify potential interactions.



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22 12, 2025

What Happens to Your Blood Pressure When You Drink Green Tea

By |2025-12-22T18:53:33+02:00December 22, 2025|Dietary Supplements News, News|0 Comments


Green tea is a popular drink that contains plant compounds linked to better heart health. Research shows it may help lower blood pressure slightly, however, drinking too much could lead to issues such as caffeine side effects or reduced iron absorption. 

Blood pressure refers to the amount of force that’s exerted on the walls of your blood vessels. When that pressure is high for too long, it can damage organs and raise your risk of heart disease, stroke, and more.

Along with other factors, stiff blood vessels can cause high blood pressure (hypertension). But that’s where green tea comes in—it contains antioxidants called catechins which may help the body relax blood vessels more easily. This allows for better blood flow and possibly lower blood pressure. 

Green tea also contains compounds that may be able to help lower inflammation and oxidative stress, a state where the body has too many cell-damaging compounds called free radicals. Oxidative stress and inflammation may cause damage to blood vessels, and have been linked to high blood pressure. Drinking green tea may help reduce this kind of damage to your cells, protecting heart function in the process.

A 2025 review concluded that green tea supplements may lead to small but meaningful decreases in blood pressure. Plus, a 2022 study found that green tea drinkers with high blood pressure did not have any increased risk of mortality from heart disease.

Though some research suggests the antioxidants and anti-inflammatory compounds in green tea may support healthy blood pressure, it’s important to note that green tea does not work like medication.

Plus, some research has even found that heavy green tea consumption may slightly raise the risk of hypertension, so more studies are needed.

However, moderate amounts of green tea can be part of a healthy diet, and may add up to meaningful changes in heart health when combined with exercise, healthy eating, and lower sodium intake.

Green tea is largely considered safe for most people. However, drinking too much can lead to health concerns, including:

  • Iron absorption issues: Green tea contains compounds called polyphenols that may interrupt the body’s ability to absorb nonheme iron, or iron from plant sources. Some research found drinking tea with meals reduced iron absorption by at least 85%. Green tea usually isn’t associated with iron deficiency, though drinking large amounts could raise your risk.
  • Caffeine side effects: One 12-ounce cup of green tea contains around 37 milligrams of caffeine, which is significantly less than a standard cup of coffee. Still, drinking too much green tea could lead to caffeine side effects such as fast heartbeat, nervousness, headaches, or trouble sleeping.
  • Medication interactions: At very high doses, green tea may interact with nadolol, a drug for heart issues and hypertension. Other research suggests catechins, the antioxidant found in green tea, may interact with other medications, including chemotherapies, high cholesterol drugs, antibiotics, and more.

If you take green tea supplements, which are much more concentrated than a cup of tea, there are other potential risks. Higher doses of green tea supplements to liver toxicity, elevated blood pressure, nausea, and stomach pain.

For most healthy adults, drinking a few cups of green tea per day is considered safe, plus it may provide heart health benefits. But people who are pregnant, have low iron levels, or are sensitive to caffeine should consider limiting their intake. It’s always a good idea to speak with a healthcare provider before adding teas or supplements to your diet.



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