About Editorial team of BIPNs

Main team of content of bipns.com. Any type of content should be approved by us.
5 08, 2025

Alpen Labs Launches Bitcoin Public Testnet for DeFi Infrastructure

By |2025-08-05T06:53:47+03:00August 5, 2025|News, NFT News|0 Comments


– Alpen Labs launches Bitcoin public testnet to enable decentralized finance (DeFi) applications like trading and stablecoin usage directly on the blockchain.

– The ZK-rollup-based testnet with EVM compatibility allows developers to build on-chain financial tools while maintaining Bitcoin’s security and reducing costs.

– BTC-backed stablecoin Bitcoin Dollar (BTD) and lending functionality aim to replace intermediary-dependent financial services with peer-to-peer solutions.

– Founded by MIT graduates and backed by top VCs, Alpen’s initiative aligns with growing institutional interest in Bitcoin’s infrastructure beyond its store-of-value role.

– This development signals Bitcoin’s evolution into a functional financial platform, potentially reshaping its role in the broader ecosystem through native on-chain services.



Source link

5 08, 2025

“ProZenith Reviews and Complaints” Search

By |2025-08-05T06:47:45+03:00August 5, 2025|Dietary Supplements News, News|0 Comments


Los Angeles, Aug. 04, 2025 (GLOBE NEWSWIRE) —

2025 Report: Search Trends for “ProZenith Reviews and Complaints” Reflect Rising Curiosity About Clean Energy Supplements

DISCLAIMER: This article is for informational purposes only. It does not provide medical advice, diagnosis, or treatment. Always consult a licensed healthcare provider before starting any new supplement, wellness product, or routine. Statements within this article reflect public commentary and research summaries, and are not intended to replace professional guidance or regulatory approval.

North American consumers are spending more time researching ingredients, formulas, and refund policies before purchasing any supplement — especially those related to energy, metabolism, or appetite awareness in 2025.

According to Google Trends and keyword tracking tools, search interest in phrases like “ProZenith reviews,” “clean energy supplements,” and “non-stimulant weight loss pills” has seen a notable uptick since Q1. This reflects a broader industry shift away from stimulant-heavy solutions and toward ingredient-first formulas focused on metabolic flexibility.

Explore the Full ProZenith Formula

View Full Scientific Review on Yahoo Finance

Pink Salt Trick Recipe for Weight Loss – Trending Wellness Strategy on Yahoo Finance

GlobeNewswire Report: Pink Salt Recipe for Weight Loss Spotlighted in Consumer Metabolic Reset Briefing

As consumers search deeper into the landscape of wellness formulations, they’re comparing not just brands, but underlying philosophies — including label clarity, refund structures, and the presence or absence of artificial stimulants. The increase in interest around specific branded terms — including “ProZenith complaints,” “ProZenith ingredients,” and “ProZenith metabolism support” — represents not consumer skepticism, but deeper decision-making patterns. These behavioral signals mirror a larger cultural shift toward empowerment through research.

Why Ketone-Based Supplementation Is Gaining SEO and Search Momentum

Interest in exogenous ketones like beta-hydroxybutyrate (BHB) continues to grow, particularly in online forums and biohacking communities. Recent publications from researchers such as Cahill GF Jr. and Volek JS have highlighted BHB’s role as a preferred fuel source during low-glucose states, promoting fat oxidation and supporting energy balance.

According to “Beta-Hydroxybutyrate: Its Role in Fat Metabolism and Weight Loss” (Cahill, 2017) and “Ketone Bodies as a Fuel Source” (Volek, 2012), BHB supplementation may allow users to experience the metabolic benefits of ketosis without adhering to a strict ketogenic diet. This has sparked mainstream curiosity about ketone salts in supplement form, especially among those practicing intermittent fasting, low-carb eating, or metabolic cycling.

Google search trends reinforce this interest, with increasing queries for:

  • “Does BHB help you lose weight?”
  • “ProZenith ketone ingredients”
  • “Non-caffeine metabolism support”

These trending topics show that consumers are actively looking to understand whether BHB, magnesium, and turmeric-based formulations align with their energy and body composition goals.

Ingredient Clarity: A New Standard for Consumer Trust

Transparency is fast becoming one of the most important differentiators in the supplement industry. In ProZenith’s case, label simplicity — with each active ingredient clearly listed and explained — mirrors the preferences revealed in studies such as Barbagallo and Dominguez (2010), who emphasized the importance of magnesium in metabolic health, and DiNicolantonio and O’Keefe (2018), who connected magnesium to improved fat metabolism and glucose control.

Each bottle of ProZenith contains a blend of:

  • Magnesium Beta Hydroxybutyrate
  • Calcium Beta Hydroxybutyrate
  • Sodium Beta Hydroxybutyrate
  • Turmeric extract (95% curcuminoids)
  • BioPerine® (black pepper extract standardized to 95% piperine)

The selection of these ingredients is not coincidental. Research continues to explore their potential benefits:

  • Turmeric: Long known for its anti-inflammatory properties, turmeric standardized to 95% curcuminoids has been explored for its role in metabolic and digestive health (Youm et al., 2015).
  • Piperine: Included to enhance absorption of turmeric and other actives, based on pharmacokinetic studies referenced in publications such as Nutrition Research (2015).
  • BHB salts: Investigated for their impact on ketone levels, fat oxidation, and appetite suppression (Stubbs et al., 2018; Gibson et al., 2015).

These ingredients, paired in a simplified format, reflect what studies from Clarke (2019) and Egan (2017) call a “modular supplement stack” — optimized for consistency and integration into diverse routines.

Emerging Research on Appetite Control, Hydration, and Cognitive Energy

In addition to metabolism and fat utilization, BHB’s potential role in appetite regulation has gained attention. Gibson et al. (2015) and Sumithran et al. (2013) observed that exogenous ketones, when introduced in controlled doses, may contribute to satiety and reduce cravings — both of which play a significant role in sustainable fat loss strategies.

From a hydration and mineral balance perspective, sodium and calcium salts — included in ProZenith’s matrix — are not simply passive carriers. Studies such as He and MacGregor (2018) and Houston (2010) emphasize the relevance of sodium in fluid retention, electrolyte balance, and neuromuscular function. When paired with magnesium, this balance can help support energy production, especially under caloric restriction or fasting conditions.

Additional findings from Evans et al. (2017) and Egan et al. (2017) suggest that ketone supplementation may enhance endurance and perceived energy levels during extended activity windows, supporting a growing interest in clean energy support for physical performance and daily focus.

Discover the Research-Driven Benefits of ProZenith

Read the Pink Salt Trick Strategy for Metabolism Support

Explore the Metabolic Reset Briefing Featuring ProZenith

The Link Between Ketone Supplementation and Metabolic Flexibility

As public interest in body recomposition and intermittent fasting continues to surge, researchers are drawing renewed attention to how metabolic flexibility—the ability to efficiently switch between energy sources—can be supported through exogenous ketone intake.

In the 2014 paper “Ketogenic Diets and Their Effectiveness in Promoting Weight Loss,” Paoli et al. observed that nutritional ketosis facilitated improvements in both body composition and metabolic biomarkers. But more recently, supplemental ketone salts have gained interest for enabling similar pathways without requiring strict adherence to a ketogenic diet.

According to “Exogenous Ketones and Fat Burning” (Stubbs et al., 2018), beta-hydroxybutyrate plays a central role in enhancing fat oxidation, even when carbohydrate intake is not severely limited. Their research demonstrated that ketone salts could raise circulating ketone levels enough to engage fat-burning pathways, offering a new path forward for those unable or unwilling to sustain low-carb diets long-term.

What’s more, the appetite-modulating effects of BHB—cited in multiple studies including Gibson et al. (2015) and Sumithran et al. (2013)—are becoming a core area of focus for consumers seeking sustainable hunger control. Unlike stimulants, which may suppress appetite artificially through cortisol spikes or nervous system activation, ketones appear to regulate appetite through more natural, metabolic signaling pathways.

This distinction is a key reason terms like “non-stimulant weight loss support” and “appetite control without caffeine” are gaining traction in SEO keyword trends. Platforms like Reddit, TikTok, and Google Discover have begun surfacing posts that compare BHB stacks for focus, appetite awareness, and fat utilization—driving the visibility of formulas like ProZenith.

As emphasized in the Journal of Nutrition and Metabolism (Volek & Phinney, 2012), the potential for exogenous ketones to support metabolic homeostasis — without triggering the energy crashes often associated with high-sugar or caffeine-heavy products — has positioned BHB supplements as a rising category in the functional nutrition market.

DISCLAIMER: All scientific findings referenced herein are for educational and informational purposes only. Individual responses to supplements may vary, and none of the referenced studies should be interpreted as product-specific claims. Always consult your healthcare provider before making dietary or supplement decisions.

Gut Microbiome, Fasting, and the New Era of Self-Guided Health Tools

Wellness-savvy consumers are looking beyond surface-level benefits and asking deeper questions about what happens inside the body — particularly in the gut and endocrine systems — when introducing new formulations in 2025. This shift has led to a surge in demand for non-pharmaceutical interventions that support the body’s internal balance without triggering dependence or overstimulation.

Recent microbiome-focused research has illuminated how dietary changes — particularly ketogenic or low-carbohydrate dietary patterns — can impact gut bacteria composition. In “Gut Microbiome Changes During Ketogenic Diets and Weight Loss” (Ang et al., Cell Metabolism, 2020), researchers found that participants entering nutritional ketosis experienced notable shifts in bacterial populations associated with energy utilization and inflammatory regulation.

Although these findings were not supplement-specific, they have opened the door for consumers to explore the ways in which BHB, magnesium, and turmeric might interact with lifestyle changes, such as fasting or carb cycling. The intersection of these tools is what defines the modern self-optimizer: someone who is less interested in isolated ingredients and more interested in synergy, personalization, and long-term sustainability.

Explore the Synergistic Potential of ProZenith’s Formula

Fasting, in particular, has become a widely adopted strategy in both weight loss and mental clarity circles. A major review from the New England Journal of Medicine (Mattson et al., 2019) linked intermittent fasting to improvements in insulin sensitivity, metabolic signaling, and body composition. When BHB salts are introduced during fasting windows, many anecdotal users report improved energy and reduced hunger, though more controlled studies are needed to fully validate these outcomes.

That’s where the distinction becomes critical for regulatory compliance: it’s not about saying what ProZenith does, but recognizing what users are curious about.

Across platforms like YouTube, TikTok, and health-focused Subreddits, search terms like:

  • “Can you take BHB while fasting?”
  • “Is turmeric good for the gut?”
  • “What’s the difference between ketone salts and esters?”

are showing sharp increases. The prozenith.com team has acknowledged this trend by making their formula transparent, modular, and easy to evaluate ingredient by ingredient — without forcing users into rigid lifestyle patterns.

Visit the Official ProZenith Site to See the Ingredient Panel

Further advancing this conversation, Clarke et al. (2019) explored how ketone supplements might impact fat oxidation during both rest and exercise states. Their findings showed that beta-hydroxybutyrate can increase fat utilization — again, not as a weight-loss drug, but as a biochemical substrate naturally produced by the body under certain conditions.

This line of research is what’s pushing “clean energy” supplements into the mainstream — especially those that skip synthetic stimulants and focus instead on biological coherence.

COMPLIANCE REMINDER: Statements made about individual ingredients or study outcomes are educational in nature and are not intended to diagnose, treat, or cure any condition. Always seek the advice of a healthcare professional before beginning any new health program or supplement regimen.

Why Mineral Synergy Still Matters in 2025

Although much of the public’s attention has shifted toward novel biohacking compounds and AI-driven health platforms, foundational mineral nutrition continues to shape the discussion on metabolic performance and cognitive clarity — especially among those exploring ketogenic or intermittent fasting protocols.

In formulations like ProZenith, the inclusion of magnesium, calcium, and sodium beta-hydroxybutyrate salts is more than just a delivery mechanism. Each of these electrolytes plays a distinctive role in optimizing how ketones interact with the body.

According to DiNicolantonio and O’Keefe (2018), magnesium acts as a cofactor in more than 300 enzymatic reactions, many of which are directly tied to insulin sensitivity, fat metabolism, and ATP generation. The relevance of magnesium in weight management was further reinforced in a study by Barbagallo and Dominguez (2010), which linked insufficient magnesium intake with metabolic dysfunction and reduced fat oxidation capacity.

Meanwhile, sodium and calcium — often dismissed in mainstream health media — are proving critical to energy distribution and muscle performance. He and MacGregor (2018) noted that sodium helps regulate water balance and nerve function, two factors that are especially important during caloric restriction or high-intensity training. Similarly, calcium’s relationship with body fat modulation was explored by Zemel (2004), whose study indicated that calcium intake may influence how fat is stored or oxidized.

Discover the Functional Synergy of ProZenith’s Formula

Physical Performance, Ketones, and Non-Stimulant Focus

A growing body of literature is also pointing to the role of exogenous ketones in physical performance and endurance. In “The Impact of Ketones on Physical Performance and Weight Reduction” (Evans et al., 2017), researchers found that ketone supplementation was associated with delayed fatigue and improved oxidative metabolism under aerobic conditions. These findings align with earlier data from Egan et al. (2017), who studied how ketones combined with moderate exercise could enhance fat burning and perceived energy levels.

Crucially, none of these studies treat ketones as a magic bullet. Instead, they support a nuanced perspective — one where ketone salts may assist users in transitioning more smoothly into fat-burning states, especially when combined with hydration and physical activity.

Search trend data shows that consumers are increasingly asking questions like:

  • “Should I take BHB before a workout?”
  • “Is magnesium better than caffeine for energy?”
  • “Can you burn fat while fasting if you take ketones?”

View the Official Ingredient Overview

It’s in this context that ProZenith’s non-stimulant formulation finds its relevance — not as a rapid fix, but as a modular tool aligned with modern metabolic strategies. Each mineral-bound ketone compound works in tandem to support hydration, neural firing, and energy conversion — all without relying on caffeine, yohimbine, or synthetic fat burners.

IMPORTANT NOTICE: None of the cited studies make claims about ProZenith as a finished product. They are included here as contextual insights to help consumers understand broader metabolic research themes. This article does not diagnose or recommend any treatment or supplement. All decisions about diet or supplementation should be made in consultation with a licensed professional.

The Anti-Inflammatory Conversation: Turmeric, Piperine, and Transparent Formulation

Beyond metabolism and energy, consumer interest in inflammation support has spiked in 2025 — especially among individuals focused on gut health, hormone balance, and cognitive clarity. According to Google Shopping and Reddit keyword tracking tools, searches like:

  • “Turmeric for weight loss inflammation”
  • “Best absorption for curcumin”
  • “Piperine effects with turmeric supplements”

…have risen steadily alongside branded queries like “ProZenith turmeric” and “ProZenith vs other keto pills.”

This shift reflects not just curiosity about results, but deeper attention to bioavailability — the degree to which ingredients are absorbed and used by the body. Curcumin (the active compound in turmeric) is notoriously difficult for the body to absorb unless paired with a delivery enhancer. That’s where BioPerine®, a patented black pepper extract standardized to 95% piperine, becomes important.

In “Anti-Inflammatory Effects of Beta-Hydroxybutyrate and Their Role in Fat Loss” (Youm et al., Nature Reviews, 2015), researchers noted that BHB has the potential to modulate inflammation-related pathways, including NLRP3 inflammasome signaling. While these findings are preliminary, they align with the broader narrative that non-stimulant supplements with metabolic support ingredients may offer secondary wellness effects worth exploring further.

Add turmeric’s benefits to that picture — as studied by Newport et al. (2015) and Evans et al. (2017) — and it’s clear why 2025 consumers are comparing ingredient stacks like never before.

Published Research on Turmeric, Piperine, and Ketone Supplementation

When Are Consumers Searching for Metabolism Support?

Search trend data from Google’s Health Vertical shows seasonal spikes in metabolism-related searches each year between mid-August and early November, as well as January resolution periods. In 2025, interest in the following keyword patterns is up over 40% from the previous year:

  • “non-stimulant energy pills fall 2025”
  • “clean metabolism support for women”
  • “intermittent fasting supplement stack”
  • “buy BHB ketones with refund guarantee”

ProZenith’s keyword volume has followed this pattern, with trending queries like “ProZenith Labor Day sale” and “ProZenith 2025 return policy” starting to surface across forums, review sites, and Reddit health communities.

These signals suggest that users are searching for:

  • Seasonal boost strategies without caffeine crashes
  • Transparent refund protection in case the product isn’t a fit
  • Products that support longer-term body composition goals without dependency or withdrawal effects

The Refund Guarantee as a Trust Signal

For YMYL compliance, trust and transparency are paramount — not just in ingredients but in purchase logic. Studies in eCommerce behavior show that clearly stated refund terms reduce perceived risk and increase buyer confidence, especially in competitive supplement categories.

With ProZenith, one of the most-searched phrases is “ProZenith refund policy,” indicating a desire for reassurance. While the actual refund terms are outlined on the brand’s site, it’s this pre-purchase intent that matters: modern consumers want full information before they commit.

This demand for pre-checkout clarity is redefining how brands earn loyalty — not through endorsements or influencer videos, but through visible, auditable claims in 2025.

Access Refund Terms and Ingredient Transparency Page

Contact & Company Information

For more information on ingredient transparency, refund questions, or label access, consumers can contact:

Support Email:

  • Product Support: support@getprozenith.com
  • Order Support: support@clickbank.com

Phone Numbers:

  • (US): +1 800-390-6035
  • (INTL): +1 208-345-4245
  • Hours: 9am–5pm EST, Monday through Friday

Return Address: ProZenith Fulfillment Dept., Boise, ID 83702

Final Disclaimer

This article is intended for informational purposes only. It does not constitute medical advice, treatment, or diagnosis. None of the ingredients or compounds discussed are guaranteed to produce results, and individual responses will vary. Statements about studies or ingredient functionality are summaries of publicly available research, not product endorsements. Always consult a healthcare provider before beginning any new health, fitness, or supplementation routine. This article is not a review or recommendation of any brand or product.


            



Source link

5 08, 2025

Solana Price Prediction: Golden Cross and Liquidation Squeeze Set Stage for Next Rally

By |2025-08-05T06:40:50+03:00August 5, 2025|Crypto News, News|0 Comments

Solana is gaining momentum after a key breakout, with technical signals and real-world adoption hinting at a potential major rally ahead.

After days of corrective price action, Solana is starting to flip the script. The token has bounced off key support near $155 and is now showing signs of renewed strength, both on the charts and in real-world adoption.

Solana’s Adoption Goes Corporate

In a surprising move, Artelo Biosciences has adopted Solana as a reserve asset, marking a major step in real-world crypto adoption. The pharma firm raised $9.475M through a private placement to back this treasury strategy, making it the first publicly traded biotech company to integrate SOL into its financial reserves. This marks a corporate headline, and it shows the growing confidence in Solana’s longer-term perspective.

While short-term price movement may not instantly reflect this news, structurally, this kind of adoption can build long-term investor trust and open the door for a broader bullish trend.

Solana Price Signals the Bottom May Be In!

Solana’s price is starting to show strong signs of reversal, with NoirBit’s latest chart pointing to a confirmed bottom formation. The price has broken out of a multi-month downtrend and is now riding a clean ascending support line. Two smaller consolidation phases are marked clearly within this climb, suggesting healthy continuation as buyers gradually regain control.

Solana breaks out of a multi-month downtrend, forming a clean ascending structure with potential targets up to $250. Source: NoirBit via X

The key zone to hold now is around $160 to $155, just above the recent breakout level. If SOL maintains this structure, the path towards $195, followed by $230 and $250, appears open. It’s a technically clean chart and strong structure. When paired with Solana’s growing real-world adoption, this lends extra weight to the long-term upside case.

Solana Faces Major Liquidation Wall Near $166.8

As Solana builds strength through both corporate adoption and technical structure, fresh data from CoinAlytix adds another layer: the futures market is heating up. According to CW8900, Solana’s futures volume is now the third largest among all crypto assets, highlighting growing speculative interest. The heatmap shows a thick concentration of open short positions around the $166.8 mark, setting up a potential liquidation cluster if the price pushes through.

Solana Price Prediction: Golden Cross and Liquidation Squeeze Set Stage for Next Rally

Solana’s futures heatmap reveals a heavy short buildup near $166.8, hinting at a potential liquidation squeeze. Source: CW8900 via X

This aligns neatly with the earlier view of a bottom forming and the steady accumulation trend. If Solana reclaims $166.8, the unwinding of these shorts could act as a fuel injection, propelling the price towards higher resistance zones.

Solana Price Prediction: Long-Term Structure Points to $300–$400

As Solana continues building strength across spot, futures, and adoption fronts, Jesse Peralta’s latest long-term chart presents a compelling macro case. The trendline stretching from Solana’s earliest accumulation phases remains intact, and price has consistently respected this diagonal base throughout bull and bear cycles. This kind of structure often leads to one of the strongest directional rallies.

Solana Price Prediction: Long-Term Structure Points to $300–$400

Solana maintains a macro uptrend dating back to 2020, with its structural base pointing to a potential move towards $300–$400. Source: Jesse Peralta via X

What’s particularly notable is that this ascending trendline has been in play since 2020, surviving multiple market cycles without a significant break. Each touchpoint reinforces its reliability as a structural base and opens the idea of a major bullish breakout ahead. If Solana continues to respect this long-standing diagonal support, the next leg up could realistically stretch towards the $300 to $400 zone, especially as fundamentals and sentiment align.

Solana Prepares for Imminent Golden Cross

Solana’s daily chart is starting to show early signs of a potential golden cross, with the shorter-term EMAs curling upward toward the longer-term ones. The convergence of the 50-day and 200-day exponential moving averages hints at an impending bullish crossover, typically seen as a trend-confirming signal in technical analysis. As SOL continues to trade above key support zones, this golden cross setup could reinforce the broader momentum already highlighted in previous sections.

Solana Prepares for Imminent Golden Cross

Solana’s EMAs are converging toward a golden cross, signaling growing bullish momentum if key supports hold. Source: Altcoin Sherpa via X

Final Thoughts: Can Solana Flip Momentum Into a Full-Blown Rally?

Solana is shaping up to be one of the most well-rounded narratives in crypto right now, supported by corporate adoption, clean technical breakouts, and even a potential golden cross brewing on the charts. With futures volume rising and key levels like $166.8 acting as pivot zones, the stage is set for a possible wave of liquidations that could drive the price higher.

Still, for Solana to truly break into the $300 to $400 range, it must hold that critical $155 to $160 zone and maintain its structural integrity. The long-term trendline dating back to 2020 remains a powerful base, and if respected, it could serve as the launchpad for Solana’s next major leg up.



Source link

5 08, 2025

Supplements That May Help Lower Your Cholesterol

By |2025-08-05T04:46:45+03:00August 5, 2025|Dietary Supplements News, News|0 Comments


  • Dietitians recommend supplements like omega-3 fatty acids and soy protein to reduce your cholesterol.
  • Experts also recommend talking with your provider about plant sterols and psyllium husks.
  • Other lifestyle changes, like quitting smoking and reducing saturated fat in your diet, can help.

High cholesterol affects about 10% of adults living in the U.S., but experts estimate that many more have high cholesterol levels and have no idea. High cholesterol is silent—the only way to tell if you have elevated numbers ( ≥240 mg/dL of total cholesterol) is by getting a simple blood test. It’s important to know if your cholesterol is high because hypercholesterolemia increases your risk for other conditions, like atherosclerosis, or the buildup of plaque in your arteries that can lead to a heart attack and/or stroke. While there are certain risk factors, like your age and genetics, that you can’t control, there are other factors, like your diet and lifestyle, that you can.

Focusing on nutrient-dense foods like whole grains, fruits and vegetables, in addition to moving more, should be the first line of defense in helping manage high cholesterol levels. But there are science-supported supplements that may also lend support in managing your cholesterol levels. Lauren Manaker, M.S., RDN, LDN, CLEC, shares, “A balanced diet is the foundation for managing cholesterol, while supplements act as a helpful safety net to fill in any gaps.”

Registered dietitians agree that these four supplements may be worth considering if you’ve done everything you can to manage your cholesterol levels and still aren’t seeing the numbers you’d like. 

Omega-3s DHA + EPA 

DHA, docosahexaenoic acid, and EPA, eicosapentaenoic acid, are two omega-3 fatty acids that continue to top the charts as one of the most recommended supplements for better heart health—and for good reason. A meta-analysis of 90 randomized controlled studies found a dose-response relationship of supplementing with these fats and improved blood lipids. Both DHA and EPA helped lower both triglycerides and non-HDL cholesterol levels. Note, triglycerides aren’t cholesterol; they’re a different lipid. Having high triglycerides means you’re more likely to have high cholesterol, placing you at higher risk for heart disease. 

While you can get DHA and EPA through food sources, like salmon, sardines, herring and mackerel, most Americans are falling short on including them in their diet. Enter the supplement safety net. Toby Amidor, M.S., RD, shares, “Most people aren’t getting enough DHA and EPA omega-3 fats. That’s where a supplement can be helpful. In fact, research found that taking more than 2 grams per day of a DHA and EPA combined supplement can help lower blood lipids.”

Plant Sterols 

Plant sterols are compounds found in plants that have a similar structure to cholesterol. Because of this, plant sterols can help block cholesterol absorption in the gut, which in turn helps keep blood cholesterol levels in check. Manaker shares, “Plant sterols work by competing with cholesterol for absorption in the digestive system. This means less cholesterol gets absorbed into your bloodstream, which can help lower LDL (“bad”) cholesterol levels without affecting HDL (“good”) cholesterol.”

A meta-analysis explored a variety of nutraceuticals, including plant sterols, and the impact they had on blood lipid levels. While research designs are challenging to do on humans with this particular supplement, the body of research continues to support the inclusion of plant sterols as part of an intervention designed to lower cholesterol levels. 

The National Center for Complementary and Integrative Medicine also notes that plant sterol supplements have shown promise in reducing cholesterol levels when taken with meals. While they are overall safe and pose minimal risk, individuals with specific genetic conditions may be at an increased risk of heart disease when the supplement is consumed in excess.

Psyllium Husk 

This popular fiber supplement has made a name for itself in weight loss, cholesterol management and blood sugar control. Amidor recommends this supplement for cholesterol management, given its longstanding research in the area. In fact, a review highlights the cholesterol-lowering effects this supplement has on humans. Notably, the soluble fiber in psyllium husk helps lower LDL cholesterol levels through binding to bile acids in the intestines. This helps remove them from the body, which in turn lowers cholesterol levels.

Since there are some downsides to this supplement, like its interaction with other medications and ability to hinder absorption of other nutrients and calories from foods, it’s best to work with your provider to identify the dosage that may be best for you.  

Soy Protein 

Soy protein has been shown to have a positive impact on cholesterol levels. A systematic review and meta-analysis explored the impact that soy protein supplementation had on postmenopausal women and their cholesterol levels. Scientists found soy protein supplementation demonstrated a significant impact on cholesterol levels, noting a reduction of total cholesterol levels and an increase of HDL cholesterol levels (the “good” cholesterol).

Manaker shares that soy protein’s impact on cholesterol levels is due to its ability to “reduce the liver’s production of cholesterol and increase the clearance of LDL cholesterol from the bloodstream.”

One important point when it comes to soy protein supplementation is that the research shows food sources of soy protein yield better results than a pill form of soy protein, likely due to the other nutrients found in soy products. Manaker recommends considering more tofu, soy milk, edamame and soy protein powders in your diet to start. The good news, too, is that there is little risk associated with consuming more soy protein in your diet (unless you have a soy protein allergy).

Other Strategies to Support Cholesterol Levels

While supplements can be used as a safety net, they are not a replacement for a healthy diet or lifestyle habits that have proven to support cholesterol levels. Amidor and Manaker recommend considering these other strategies to support healthy cholesterol levels: 

  • Limit saturated fat. Saturated fat can raise LDL cholesterol levels, impacting your heart health. The Dietary Guidelines for Americans recommend consuming no more than 10% of your daily calories from saturated fat. To make smarter choices, choose lean and extra-lean cuts of meat and trim visible fat off your meat when preparing it. Reducing consumption of cheese, full-fat dairy and processed meats is also a great way to reduce saturated fat in your diet. 
  • Eat more fruits and vegetables. Filled with fiber and antioxidants, fruits and vegetables help improve diet quality and lower one’s risk of chronic disease. Yet, only 10% of people in the U.S. eat the recommended daily fruits and veggies. Make a conscious effort to add one serving of either a fruit or veggie at every meal and snack.
  • Enjoy fatty fish (like salmon) twice per week. Up your intakes of those omega-3 fatty acids DHA and EPA by consuming fatty fish at least twice per week. Enlisting the help of canned salmon is an excellent dietitian-approved swap to make mealtime magic happen with these fish. 
  • Choose foods with the American Heart Association’s Heart Check Mark. An easy way to navigate the market is by looking for foods with the heart-check logo. This means items have been vetted by the American Heart Association and have lower fat, sodium and added sugar than other items. But, as with all foods, even a heart-check approved snack food should still be consumed in moderation. 
  • Exercise regularly. Regular movement is an excellent way to improve cholesterol levels and can help manage stress levels (another factor that can indirectly affect your lipid levels). In fact, research shows that moderate and high-intensity movement improves HDL cholesterol levels (the good one). Starting small with a walking routine is a wonderful way to invite more movement into your day. 
  • Quit smoking and vaping, and limit alcohol. Smoking and drinking both increase one’s cholesterol levels. Quitting smoking is a great idea if you have high cholesterol. Alcohol is a known carcinogen and should be reduced. If the thought of giving it up stresses you out more, stick to standard serving sizes when you do enjoy a glass of wine (which is a 5-ounce pour).

Meal Plan to Try

Our Expert Take

Nutrition and lifestyle play a critical role in managing high cholesterol levels. But there are four supplements that may offer some benefits, too. For example, nutrition experts recommend adding the omega-3 fatty acids DHA and EPA, as well as soy protein, into your regular routine. Talk with your provider if you want to consider adding psyllium husk or plant sterols as part of your cholesterol-lowering plan

Working with your individual provider to tailor a plan for you is the best way to ensure you learn how to proactively manage your cholesterol long-term in the way that’s right for you. Other lifestyle changes, such as quitting smoking, limiting alcohol intake, getting regular exercise and reducing saturated fat in your diet, may also benefit your cholesterol levels.



Source link

5 08, 2025

Ethereum (ETH) Price Prediction for August 4 — TradingView News

By |2025-08-05T04:39:47+03:00August 5, 2025|Crypto News, News|0 Comments

The market has changed to green after the weekend’s correction, according to CoinMarketCap. CoinMarketCap”>

ETHUSD

Ethereum ETHUSD is one of the greatest gainers today, rising by 3.89%.TradingView”>

On the hourly chart, the rate of ETH is rising after a resistance breakout. If the daily bar closes around current prices, there is a high chance to see a test of the $3,700 mark soon.TradingView”>

On the longer time frame, the price of the main altcoin is going up after yesterday’s bullish closure. 

If bulls can hold the gained initiative, traders may witness an ongoing upward move to the $3,800 zone.TradingView”>

From the midterm point of view, it is too early to make any long-term predictions. The volume is falling, which means sideways trading in the range of $3,500-$3,800 is the more likely scenario.

Ethereum is trading at $3,650 at press time.

Source link

5 08, 2025

Scallops, green tea fuel 15% growth in Japan food exports

By |2025-08-05T02:45:50+03:00August 5, 2025|Dietary Supplements News, News|0 Comments


Shipments top $5bn in Jan-June half, but increase still slow to meet 2030 target

Scallops shipped to the U.S. helped underpin Japan’s record food exports in the first half. (Photo by Kotose Hamano)

TOKYO — Japan’s exports of agricultural, forestry and fishery products hit an all-time high for the January-June period this year, driven by strong U.S. demand for scallops and green tea and robust Chinese buying of sake.





Source link

5 08, 2025

Bitcoin (BTC) Price Prediction for August 4 — TradingView News

By |2025-08-05T02:38:50+03:00August 5, 2025|Crypto News, News|0 Comments

All top 10 coins have returned to the green zone on the first day of the week, according to CoinStats.CoinStats”>

BTCUSD

The price of Bitcoin BTCUSD has risen by 1.36% since yesterday.TradingView”>

On the hourly chart, the rate of BTC is going up after a breakout of the $114,926 level. If buyers can hold the gained initiative, the rise is likely to continue to the $116,000 mark.TradingView”>

On the longer time frame, buyers are trying to seize the initiative. However, traders might need more time to accumulate energy for a further move. 

In this regard, consolidation in the area of $114,000-$117,000 is the most likely scenario.TradingView”>

From the midterm point of view, neither bulls nor bears are controlling the situation on the market. This statement is confirmed by falling volume. All in all, traders are unlikely to see increased volatility anytime soon.

Bitcoin is trading at $115,288 at press time.

Source link

5 08, 2025

Natural Gas Price Forecast: Breaks Key Support, Sellers in Control

By |2025-08-05T00:49:04+03:00August 5, 2025|Forex News, News|0 Comments


Monthly Bear Trigger

Furthermore, a bearish monthly breakdown (not shown) triggered today as last month’s low of $2.97 was breached. That put natural gas at four-month low and falling. Prior monthly support was seen at the $2.86 low in April, and it looks likely to be challenged if downward pressure remains. That is a five-month low. The trajectory of the current decline also looks like it may be heading to a test of support around the 20-Month MA, now at $2.85. Since the two price levels are so close together, that price zone deserves particular attention, if it is approached.

Symmetry Points to $2.63

In addition, there is an initial target for a falling ABCD pattern (purple) at $2.63. That is where there will be symmetry in price compared to the first leg down (AB). Once that occurs a key potential pivot is identified. Finally, there is a second 78.6% retracement level, a little lower at $2.53. It measures a larger upswing than the prior 78.6% level.

Fast Recovery Could Change Bearish Outlook

An alternative to the above bearish scenario would be a relatively quick recovery of the AVWAP line and a daily close above it. That should then be followed by a recovery of the long-term uptrend line and a close above it, as well as above the prior trend low at $2.97. A bearish closing price today, in the lower third of the day’s range, keeps the sellers in charge and the lower price targets in sight.

For a look at all of today’s economic events, check out our economic calendar.



Source link

5 08, 2025

Development of molecular diagnostic methods to distinguish acerola species for quality assurance of food, dietary supplements and natural health products

By |2025-08-05T00:44:49+03:00August 5, 2025|Dietary Supplements News, News|0 Comments


  • Laurindo, L. F. et al. Health benefits of acerola (Malpighia spp) and its by-products: A comprehensive review of nutrient-rich composition, pharmacological potential, and industrial applications. Food Biosci.https://doi.org/10.1016/j.fbio.2024.105422 (2024).

    Article 

    Google Scholar
     

  • Uma Maheswari, M., Arumugam, T. & Lincy Sona, C. Fruits and vegetables as superfoods: Scope and demand. Pharma Innov. J.10, 119–129 (2021).


    Google Scholar
     

  • Li, D. Z. et al. Comparative analysis of a large dataset indicates that internal transcribed spacer (ITS) should be incorporated into the core barcode for seed plants. Proc. Natl. Acad. Sci. U. S. A.108, 19641–19646 (2011).

    ADS 
    CAS 

    Google Scholar
     

  • FMI. Processed Superfruit Market Outlook from 2025 to 2035. (2025). https://www.futuremarketinsights.com/reports/processed-superfruits-market (2025).

  • Fernández-Ríos, A. et al. A critical review of superfoods from a holistic nutritional and environmental approach. J. Clean. Prod. Vol. https://doi.org/10.1016/j.jclepro.2022.134491 (2022). 379 Preprint at.

    Article 

    Google Scholar
     

  • Prakash, A. & Baskaran, R. Acerola, an untapped functional superfruit: A review on latest frontiers. J. Food Sci. Technol.55, 3373–3384. https://doi.org/10.1007/s13197-018-3309-5 (2018).

    Article 
    CAS 

    Google Scholar
     

  • Mezadri, T., Villaño, D., Fernández-Pachón, M. S., García-Parrilla, M. C. & Troncoso, A. M. Antioxidant compounds and antioxidant activity in acerola (Malpighia emarginata DC.) fruits and derivatives. J. Food Compos. Anal. 21, 282–290 (2008).

    CAS 

    Google Scholar
     

  • Righetto, A. M., Netto, F. M. & Carraro, F. Chemical composition and antioxidant activity of juices from mature and immature acerola (Malpighia emarginata DC). Food Sci. Technol. Int.11, 315–321 (2005).

    CAS 

    Google Scholar
     

  • McGuffin, M., Tucker, A. & L., A. Y. J. T. K. Herbs of Commerce (American Herbal Products Assocation, 2000).

  • Duke, J. A. CRC Handbook of Alternative Cash Crops (CRC, 1993).

  • Rezende, Y. R. R. S., Nogueira, J. P. & Narain, N. Comparison and optimization of conventional and ultrasound assisted extraction for bioactive compounds and antioxidant activity from agro-industrial acerola (Malpighia emarginata DC) residue. LWT85, 158–169 (2017).

    CAS 

    Google Scholar
     

  • De Aparecida, S. et al. Antioxidant activity, ascorbic acid and total phenol of exotic fruits occurring in Brazil. Int. J. Food Sci. Nutr. 60, 439–448 (2009).


    Google Scholar
     

  • Singh, D. R. R. West Indian Cherry ñ A lesser known fruit for nutritional security. Natural Product Radiance. 5(5), 366–368 (2006).

  • Belwal, T. et al. Phytopharmacology of acerola (Malpighia spp.) and its potential as functional food. Trends Food Sci. Technol.74, 99–106. https://doi.org/10.1016/j.tifs.2018.01.014 (2018).

    Article 
    CAS 

    Google Scholar
     

  • Paz, M. et al. Brazilian fruit pulps as functional foods and additives: Evaluation of bioactive compounds. Food Chem.172, 462–468 (2015).

    CAS 

    Google Scholar
     

  • do Rufino, M. Acerola and cashew Apple as sources of antioxidants and dietary fibre. Int. J. Food Sci. Technol. 45, 2227–2233 (2010).

    CAS 

    Google Scholar
     

  • Motohashi, N. et al. Biological activity of Barbados cherry (Acerola fruits, fruit of Malpighia emarginata DC) extracts and fractions. Phytother. Res.18, 212–223. https://doi.org/10.1002/ptr.1426 (2004).

    Article 

    Google Scholar
     

  • Leffa, D. D. et al. Corrective effects of acerola (Malpighia emarginata DC.) juice intake on biochemical and genotoxical parameters in mice fed on a high-fat diet. Mutat. Res. – Fundamental Mol. Mech. Mutagen. 770, 144–152 (2014).

    CAS 

    Google Scholar
     

  • Horta, R. N. et al. Protective effects of acerola juice on genotoxicity induced by iron in vivo. Genet. Mol. Biol.39, 122–128 (2016).

    CAS 

    Google Scholar
     

  • Düsman, E., Almeida, I. V., Tonin, L. T. D. & Vicentini, V. E. P. In vivo antimutagenic effects of the Barbados Cherry fruit (Malpighia glabra linnaeus) in a chromosomal aberration assay. Genetics Mol. Research 15(4), (2016). https://doi.org/10.4238/gmr15049036

  • Da Silva Nunes, R. et al. Genotoxic and antigenotoxic activity of acerola (Malpighia glabra L.) extract in relation to the geographic origin. Phytother. Res.27, 1495–1501 (2013).


    Google Scholar
     

  • Düsman, E. et al. Radioprotective effect of the Barbados Cherry (Malpighia glabra L.) against radiopharmaceutical Iodine-131 in Wistar rats in vivo. BMC Complement Altern Med. 14, 41 (2014). http://www.biomedcentral.com/1472-6882/14/41

  • da Silva Nunes, R. et al. Antigenotoxicity and antioxidant activity of acerola fruit (Malpighia glabra L.) at two stages of ripeness. Plant Foods Hum. Nutr.66, 129–135 (2011).


    Google Scholar
     

  • Hanamura, T., Mayama, C., Aoki, H., Hirayama, Y. & Shimizu, M. Antihyperglycemic effect of polyphenols from acerola (Malpighia emarginata DC.) fruit. Biosci. Biotechnol. Biochem.70, 1813–1820 (2006).

    CAS 

    Google Scholar
     

  • El-Hawary, S. S., El-Fitiany, R. A., Mousa, O. M., Salama, A. A. A. & El gedaily, R. A. Metabolic profiling and in vivo hepatoprotective activity of Malpighia glabra L. leaves. J. Food Biochem. 45(2), e13588. https://doi.org/10.1111/jfbc.13588 (2021).

    Article 

    Google Scholar
     

  • Costa, A. et al. Clinical, biometric and ultrasound assessment of the effects of daily use of a nutraceutical composed of lycopene, acerola extract, grape seed extract and biomarine complex in photoaged human skin. Bras. Dermatol. 87, 52–61 (2012).


    Google Scholar
     

  • Delva, L. & Goodrich-Schneider, R. Antioxidant activity and antimicrobial properties of phenolic extracts from acerola (Malpighia emarginata DC) fruit. Int. J. Food Sci. Technol.48, 1048–1056 (2013).

    CAS 

    Google Scholar
     

  • de Miskinis, A. S., Nascimento, R. & Colussi, R. L. Á. Bioactive compounds from acerola pomace: A review. Food Chemistry vol. 404 Preprint at (2023). https://doi.org/10.1016/j.foodchem.2022.134613

  • Vilvert, J. C., de Freitas, S. T., Veloso, C. M. & Amaral, C. L. F. Genetic diversity on acerola quality: A systematic review. Braz. Arch. Biol. Technol.https://doi.org/10.1590/1678-4324-2024220490 (2024).

    Article 

    Google Scholar
     

  • de Assis, S. A., Lima, D. C. & de Faria Oliveira, O. M. M. Activity of pectinmethylesterase, pectin content and vitamin C in acerola fruit at various stages of fruit development. Food Chem.74, 133–137 (2001).


    Google Scholar
     

  • dos Santos, C. P. et al. Transcriptome analysis of acerola fruit ripening: Insights into ascorbate, ethylene, respiration, and softening metabolisms. Plant. Mol. Biol.101, 269–296 (2019).


    Google Scholar
     

  • Fernandes, F. A. N., Santos, V. O., Gomes, W. F. & Rodrigues, S. Application of high-intensity ultrasound on acerola (Malpighia emarginata) juice supplemented with fructooligosaccharides and its effects on vitamins, phenolics, carotenoids, and antioxidant capacity. Processeshttps://doi.org/10.3390/pr11082243 (2023).

    Article 

    Google Scholar
     

  • Assis, S. A., De, Fernandes, F. P., Martins, A. B. G., Oliveira, O. M. M. D. F. & Acerola Importance, culture conditions, production and biochemical aspects. Fruits vol. 63 93–101 Preprint at (2008). https://doi.org/10.1051/fruits:2007051

  • Ragupathy, S. et al. Exploring DNA quantity and quality from raw materials to botanical extracts. Heliyonhttps://doi.org/10.1016/j.heliyon.2019.e01935 (2019).

    Article 

    Google Scholar
     

  • Yip, P. Y., Chau, C. F., Mak, C. Y. & Kwan, H. S. DNA methods for identification of Chinese medicinal materials. Chin. Med.https://doi.org/10.1186/1749-8546-2-9 (2007).

    Article 

    Google Scholar
     

  • Newmaster, S., Ragupathy, S. & Kress, W. J. Authentication of Medicinal Plant Components in North America’s NHP Industry Using Molecular Diagnostic Tools. in Medicinal and Aromatic Plants of North America (ed. Máthé, Á.) 325–339Springer International Publishing, Cham, (2020). https://doi.org/10.1007/978-3-030-44930-8_13

  • Kesanakurti, P. et al. Development of hydrolysis probe-based qPCR assays for Panax ginseng and Panax quinquefolius for detection of adulteration in ginseng herbal products. Foods. 10, 2705. https://doi.org/10.3390/foods10112705 (2021).

    Article 

    Google Scholar
     

  • Yu, J. et al. Progress in the use of DNA barcodes in the identification and classification of medicinal plants. Ecotoxicol Environ. Saf 208, 111691 (2021). https://doi.org/10.1016/j.ecoenv.2020.111691

  • Raclariu-Manolică, A. C. & de Boer, H. J. Chapter 8 – DNA barcoding and metabarcoding for quality control of botanicals and derived herbal products. in Evidence-Based Validation of Herbal Medicine (Second Edition) (ed. Mukherjee, P. K.) 223–238 (Elsevier, 2022). https://doi.org/10.1016/B978-0-323-85542-6.00004-4

  • Travadi, T. et al. Advancing Herbal Product Authentication: A Comprehensive Review Of DNA-Based Approach For Quality Control And Safety Assurance. Educational Adm. Theory Practices doi:https://doi.org/10.53555/kuey.v30i6(s).5308. (2024).

  • Lanubile, A., Stagnati, L., Marocco, A. & Busconi, M. DNA-based techniques to check quality and authenticity of food, feed and medicinal products of plant origin: A review. Trends Food Sci. Technol.https://doi.org/10.1016/j.tifs.2024.104568 (2024).

    Article 

    Google Scholar
     

  • Muyumba, N. W., Mutombo, S. C., Sheridan, H., Nachtergael, A. & Duez, P. Quality control of herbal drugs and preparations: The methods of analysis, their relevance and applications. Talanta Open. 4, 100070. https://doi.org/10.1016/j.talo.2021.100070 (2021).

    Article 

    Google Scholar
     

  • Ichim, M. C. & Booker, A. Chemical authentication of botanical ingredients: A review of commercial herbal products. Front. Pharmacol.https://doi.org/10.3389/fphar.2021.666850 (2021).

    Article 

    Google Scholar
     

  • Abraham, E. J. & Kellogg, J. J. Chemometric-guided approaches for profiling and authenticating botanical materials. Front. Nutr.https://doi.org/10.3389/fnut.2021.780228 (2021).

    Article 

    Google Scholar
     

  • Klein-Junior, L. C. et al. Quality control of herbal medicines: From traditional techniques to state-of-the-art approaches. Planta Med.87, 964–988. https://doi.org/10.1055/a-1529-8339 (2021).

    Article 
    CAS 

    Google Scholar
     

  • Salo, H. M. et al. Authentication of berries and berry-based food products. Compr. Rev. Food Sci. Food Saf. 20, 5197–5225 (2021).

    CAS 

    Google Scholar
     

  • García-Pérez, P., Becchi, P. P., Zhang, L., Rocchetti, G. & Lucini, L. Metabolomics and chemometrics: The next-generation analytical toolkit for the evaluation of food quality and authenticity. Trends Food Sci. Technol.https://doi.org/10.1016/j.tifs.2024.104481 (2024).

    Article 

    Google Scholar
     

  • Ichim, M. C., Scotti, F. & Booker, A. Quality evaluation of commercial herbal products using chemical methods. Crit. Rev. Food Sci. Nutr.64, 4219–4239. https://doi.org/10.1080/10408398.2022.2140120 (2024).

    Article 
    CAS 

    Google Scholar
     

  • Urumarudappa, S. K. J. et al. DNA barcoding and NMR spectroscopy-based assessment of species adulteration in the raw herbal trade of Saraca asoca (Roxb.) willd, an important medicinal plant. Int. J. Legal Med.130, 1457–1470 (2016).


    Google Scholar
     

  • Kesanakurti, P., Thirugnanasambandam, A., Ragupathy, S. & Newmaster, S. G. Genome skimming and NMR chemical fingerprinting provide quality assurance biotechnology to validate sarsaparilla identity and purity. Sci. Rep. 10, 19192. https://doi.org/10.1038/s41598-020-76073-7 (2020).

    Article 

    Google Scholar
     

  • Shirahata, T. et al. Metabolic fingerprinting for discrimination of DNA-authenticated atractylodes plants using 1H NMR spectroscopy. J. Nat. Med.75, 475–488 (2021).

    CAS 

    Google Scholar
     

  • Alberts, P. S. F. & Meyer, J. J. M. Integrating chemotaxonomic-based metabolomics data with DNA barcoding for plant identification: A case study on south-east African Erythroxylaceae species. South. Afr. J. Bot. 146, 174–186 (2022).

    CAS 

    Google Scholar
     

  • Ragupathy, S., Thirugnanasambandam, A., Vinayagam, V. & Newmaster, S. G. Nuclear magnetic resonance fingerprints and mini DNA markers for the authentication of cinnamon species ingredients used in food and natural health products. Plantshttps://doi.org/10.3390/plants13060841 (2024).

    Article 

    Google Scholar
     

  • Ragupathy, S. et al. Flower species ingredient verification using orthogonal molecular methods. Foods. 13(12), 1862.https://doi.org/10.3390/foods13121862 (2024).

    Article 

    Google Scholar
     

  • Wang, X. et al. Fruit and vegetable consumption and mortality from all causes, cardiovascular disease, and cancer: Systematic review and dose-response meta-analysis of prospective cohort studies. BMJ. 349, 5472. https://doi.org/10.1136/bmj.g4490 (2014).

    Article 

    Google Scholar
     

  • Martinez-Farina, C. F. et al. Chemical barcoding: A nuclear-magnetic-resonance-based approach to ensure the quality and safety of natural ingredients. J. Agric. Food Chem.67, 7765–7774 (2019).

    CAS 

    Google Scholar
     

  • Grazina, L., Amaral, J. S. & Mafra, I. Botanical origin authentication of dietary supplements by DNA-based approaches. Compr. Rev. Food Sci. Food Saf.19, 1080–1109. https://doi.org/10.1111/1541-4337.12551 (2020).

    Article 
    CAS 

    Google Scholar
     

  • Raclariu, A. C., Heinrich, M., Ichim, M. C. & de Boer, H. Benefits and limitations of DNA barcoding and metabarcoding in herbal product authentication. Phytochem. Anal.29, 123–128. https://doi.org/10.1002/pca.2732 (2018).

    Article 
    CAS 

    Google Scholar
     

  • Sarwat, M. & Yamdagni, M. M. DNA barcoding, microarrays and next generation sequencing: Recent tools for genetic diversity estimation and authentication of medicinal plants. Crit. Rev. Biotechnol.36, 191–203. https://doi.org/10.3109/07388551.2014.947563 (2016).

    Article 
    CAS 

    Google Scholar
     

  • Mahima, K. et al. Advancements and future prospective of DNA barcodes in the herbal drug industry. Front. Pharmacol.https://doi.org/10.3389/fphar.2022.947512 (2022).

    Article 

    Google Scholar
     

  • Osman, A. et al. Quality consistency of herbal products: chemical evaluation. In Progress in the Chemistry of Organic Natural Products 122: Botanical Dietary Supplements and Herbal Medicines (eds Kinghorn, A. D. et al.) 163–219 (Springer Nature Switzerland, 2023). https://doi.org/10.1007/978-3-031-26768-0_2.

    Chapter 

    Google Scholar
     

  • Bharti, S. K. & Roy, R. Quantitative 1H NMR spectroscopy. TrAC – Trends in Analytical Chemistry35, 5–26. https://doi.org/10.1016/j.trac.2012.02.007 (2012).

    Article 
    CAS 

    Google Scholar
     

  • Sobolev, A. P., Ingallina, C., Spano, M., Di Matteo, G. & Mannina, L. NMR-based approaches in the study of foods. Moleculeshttps://doi.org/10.3390/molecules27227906 (2022).

    Article 

    Google Scholar
     

  • Esslinger, S., Riedl, J. & Fauhl-Hassek, C. Potential and limitations of non-targeted fingerprinting for authentication of food in official control. Food Res. Int. 60, 189–204 (2014).

    CAS 

    Google Scholar
     

  • Lolli, V. & Caligiani, A. How nuclear magnetic resonance contributes to food authentication: Current trends and perspectives. Curr. Opin. Food Sci.https://doi.org/10.1016/j.cofs.2024.101200 (2024).

    Article 

    Google Scholar
     

  • Wishart, D. S. Metabolomics: Applications to food science and nutrition research. Trends Food Sci. Technol.19, 482–493. https://doi.org/10.1016/j.tifs.2008.03.003 (2008).

    Article 
    CAS 

    Google Scholar
     

  • Spiteri, M. et al. Fast and global authenticity screening of honey using 1H-NMR profiling. Food Chem.189, 60–66 (2015).

    CAS 

    Google Scholar
     

  • Giraudeau, P. Quantitative NMR spectroscopy of complex mixtures. Chem. Commun. 59, 6627–6642 (2023).

    CAS 

    Google Scholar
     

  • Holmes, E., Tang, H., Wang, Y. & Seger, C. The Assessment of Plant Metabolite Profiles by NMR-Based Methodologies. (2006). https://doi.org/10.1055/s-2006-946682

  • Mahmud, I., Chowdhury, K. & Boroujerdi, A. PTC&B Tissue-Specific Metabolic Profile Study of Moringa Oleifera L. Using Nuclear Magnetic Resonance Spectroscopy. Plant Tissue Cult. & Biotech vol. 24 (2014).

  • Rosario, L. H. et al. DNA barcoding of the Solanaceae family in Puerto Rico including endangered and endemic species. J. Am. Soc. Hortic. Sci.144, 363–374 (2019).

    CAS 

    Google Scholar
     

  • Sayed, H. A., Mostafa, S., Haggag, I. M. & Hassan, N. A. DNA barcoding of Prunus species collection conserved in the National gene bank of Egypt. Mol. Biotechnol.65, 410–418 (2023).

    CAS 

    Google Scholar
     

  • Kress, W. J., Erickson, D. L. A. & Two-Locus Global DNA barcode for land plants: the coding RbcL gene complements the Non-Coding trnH-psbA spacer region. PLoS One 2(6), e508 (2007). https://doi.org/10.1371/journal.pone.0000508

  • Baldwin, B. G. et al. The its region of nuclear ribosomal DNA: A valuable source of evidence on angiosperm phylogeny. Ann. Mo. Bot. Gard.82247. (1995).

    Article 

    Google Scholar
     

  • Kress, W. J., Wurdack, K. J., Zimmer, E. A., Weigt, L. A. & Janzen, D. H. Use of DNA Barcodes to Identify Flowering Plants. (2005). http://www.pnas.org.10.1073pnas.0503123102

  • Cheng, T. et al. Barcoding the kingdom plantae: New PCR primers for ITS regions of plants with improved universality and specificity. Mol. Ecol. Resour.16, 138–149 (2016).

    CAS 

    Google Scholar
     

  • Yao, H. et al. Use of ITS2 region as the universal DNA barcode for plants and animals. PLoS One. 5(10), e13102.https://doi.org/10.1371/journal.pone.0013102 (2010).

    Article 

    Google Scholar
     

  • Kress, W. J. Plant DNA barcodes: Applications today and in the future. J. Syst. Evol.55, 291–307. https://doi.org/10.1111/jse.12254 (2017).

    Article 

    Google Scholar
     

  • Antil, S. et al. DNA barcoding, an effective tool for species identification: A review. Mol. Biol. Rep.50, 761–775. https://doi.org/10.1007/s11033-022-08015-7 (2023).

    Article 
    CAS 

    Google Scholar
     

  • Fazekas, A. J., Kuzmina, M. L., Newmaster, S. G. & Hollingsworth, P. M. DNA barcoding methods for land plants. in 223–252 (2012). https://doi.org/10.1007/978-1-61779-591-6_11

  • Thompson, J. D., Higgins, D. G. & Gibson, T. J. CLUSTAL w: Improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice. Nucleic Acids Res.22, 4673–4680 (1994).

    CAS 

    Google Scholar
     

  • Tamura, K., Stecher, G. & Kumar, S. MEGA11: molecular evolutionary genetics analysis version 11. Mol. Biol. Evol. 38, 3022–3027 (2021).

    CAS 

    Google Scholar
     

  • Beckonert, O. et al. Metabolic profiling, metabolomic and metabonomic procedures for NMR spectroscopy of urine, plasma, serum and tissue extracts. Nat. Protoc.2, 2692–2703 (2007).

    CAS 

    Google Scholar
     

  • Nicholson, J. K., Foxall, P. J. D., Spraul, M., Farrant, R. D. & Lindon J. C. 750 MHz 1H and 1H-13 C NMR Spectroscopy of Human Blood Plasma. Anal Chem 67, 793–811 (1995).

  • Emwas, A. H. M. The strengths and weaknesses of NMR spectroscopy and mass spectrometry with particular focus on metabolomics research. in 161–193 (2015). https://doi.org/10.1007/978-1-4939-2377-9_13

  • Lê, S., Josse, J. & Husson, F. FactoMineR: an R package for multivariate analysis. J Stat. Softw 25, 1–18. (2008). https://doi.org/10.18637/jss.v025.i01

  • Bourafai-Aziez, A. et al. Development, validation, and use of 1H-NMR spectroscopy for evaluating the quality of Acerola-based food supplements and quantifying ascorbic acid. Molecules, 27(17), 5614. https://doi.org/10.3390/molecules27175614 (2022).

    Article 

    Google Scholar
     

  • Smillie, T. J. & Khan, I. A. A comprehensive approach to identifying and authenticating botanical products. Clin. Pharmacol. Ther.87, 175–186. https://doi.org/10.1038/clpt.2009.287 (2010).

    Article 
    CAS 

    Google Scholar
     

  • Mukherjee, P. K., Bahadur, S., Chaudhary, S. K., Kar, A. & Mukherjee, K. Chapter 1 – Quality Related Safety Issue-Evidence-Based Validation of Herbal Medicine Farm To Pharmain 1–28 (Elsevier Inc, 2015). https://doi.org/10.1016/B978-0-12-800874-4.00001-5

  • Govindaraghavan, S. & Sucher, N. J. Quality assessment of medicinal herbs and their extracts: Criteria and prerequisites for consistent safety and efficacy of herbal medicines. Epilepsy Behav.52, 363–371 (2015).


    Google Scholar
     

  • Dubey, N. K., Kumar, R. & Tripathi, P. Global promotion of herbal medicine: india’s opportunity. Curr Sci 86, 37–41 (2004).

  • de Medeiros, F. G. M., Pereira, G. B. C., Pedrini, M. R. S., Hoskin, R. T. & Nunes, A. O. Evaluation of the environmental performance of the production of polyphenol-rich fruit powders: A case study on acerola. J Food Eng 372, (2024). https://doi.org/10.1016/j.jfoodeng.2024.112010

  • Gomes, B. T. et al. Acerola byproducts microencapsulated by spray and freeze-drying: the effect of carrier agent and drying method on the production of bioactive powder. Int. J. Food Eng. 20, 347–356 (2024).

    CAS 

    Google Scholar
     

  • Fonseca, M. T. et al. Improving the stability of spray-dried probiotic acerola juice: A study on hydrocolloids’ efficacy and process variables. Food Bioprod. Process.147, 209–218 (2024).

    CAS 

    Google Scholar
     

  • Coelho, B. E. S. et al. Production and characterization of powdered acerola juice obtained by atomization. Acta Scientiarum – Technology 47, 1–14 (2025).

  • Walsh, K. B. & Ragupathy, S. Mycorrhizal colonisation of three hybrid papayas (Carica papaya) under mulched and bare ground conditions. Aust. J. Exp. Agric.4781. (2007).

    Article 

    Google Scholar
     

  • Dubouzet, J. G. & Shinoda, K. Phylogenetic analysis of the internal transcribed spacer region of Japanese Lilium species. Theor. Appl. Genet.98, 954–960 (1999).

    CAS 

    Google Scholar
     

  • Faller, A. C. et al. DNA quality and quantity analysis of camellia sinensis through processing from fresh leaves to a green tea extract. J. AOAC Int.102, 1798–1807 (2019).

    CAS 

    Google Scholar
     



  • Source link

    5 08, 2025

    Dogecoin Open Interest Surges Past $3B as DOGE Price Eyes $0.24 Breakout Target

    By |2025-08-05T00:38:19+03:00August 5, 2025|Crypto News, News|0 Comments

    Dogecoin

    DOGE
    $0.21



    24h volatility:
    2.7%


    Market cap:
    $30.83 B



    Vol. 24h:
    $1.73 B



    price surged 4% on Monday, August 4, reaching $0.206 after dipping to $0.19 over the weekend. This move was accompanied by a strategic bullish action in the Dogecoin futures markets, signaling more gains ahead.

    According to Coinglass, Dogecoin Open Interest rose 2.63%, surpassing $3.01 billion, while futures trading volume dropped by 8.9%. The declining volume indicates that most DOGE traders chose to hold their leveraged long positions in the last 24 hours.

    These dynamics suggest that bullish traders who held their leveraged long DOGE positions through the weekend are now sitting on notable gains.

    Dogecoin Derivative Markets Data | Coinglass, Aug 4, 2025.

    Top trader data also reflects this positive shift in market sentiment, with Binance DOGE/USDT long/short accounts at 2.7693 and OKX DOGE long/short accounts reaching 3.89. Meanwhile, top Binance DOGE trader long/short positions stand at 2.8642.

    These elevated long/short ratios amid over $100 million in intraday capital inflows confirm that top traders are overwhelmingly positioned for upside, further supporting the DOGE price recovery narrative.

    Dogecoin Price Prediction: Can DOGE Hold Above $0.21 for a Breakout Toward $0.24?

    Dogecoin price has rebounded 10.75% in two days, clawing back half of the 20% losses from last week. Technical indicators now show DOGE price testing the 5-day simple moving average (SMA) at $0.201, with the upper wick of the daily candle pressing against the 8-day SMA resistance at $0.206.

    If DOGE breaks above the 13-day SMA at $0.20958, this could open the path toward a retest of the $0.24 resistance zone and confirm a full recovery from the recent downtrend.

    Dogecoin Price Forecast | DOGEUSD

    Dogecoin Price Forecast | DOGEUSD

    Further validating the bullish narrative, Dogecoin RSI currently stands at 46.70, up from a weekend low of 39, signaling neutral momentum with room to run before overbought conditions. Conversely, if DOGE fails to close above $0.21 in the next 24 hours, sellers could resume control. A rejection could send the price back toward the $0.188 zone.

    In summary, the current Dogecoin price setup favors the bulls short-term, but needs sustained consolidation above the $0.21 area to reclaim higher ground toward $0.24.

    Best Wallet Presale Gains Momentum as Dogecoin Traders Eye Next Move

    Best Wallet is emerging as a strategic opportunity for bullish traders betting on the continuation of the current Dogecoin bull cycle. The BEST token presale has already raised over $14.25 million, attracting attention from strategic traders.

    Best Wallet Presale

    The ongoing $BEST token presale offers perks such as reduced transaction fees, early access to new crypto projects, enhanced staking rewards, and voting rights on platform governance.

    For those looking to diversify exposure and access early-stage crypto projects, the Best Wallet presale is now live. Visit the official Best Wallet website to get in.

    The post Dogecoin Open Interest Surges Past $3B as DOGE Price Eyes $0.24 Breakout Target appeared first on Coinspeaker.

    Source link

    Go to Top